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kanzure | beep | 05:36 |
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FourFire | boop | 06:11 |
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kanzure | that's boring | 10:06 |
delinquentme | ^ | 10:07 |
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kanzure | what? | 10:08 |
chris_99 | http://hackaday.io/project/1376-PyPPM%3A-A-Proton-Precession-Magnetometer-for-all! | 10:08 |
chris_99 | seems interesting | 10:08 |
kanzure | .title http://pastebin.com/2qbRKh3R | 11:01 |
yoleaux | ALL CREDIT CARD PIN CODES IN THE WORLD LEAKED | 11:01 |
chris_99 | hahaha | 11:02 |
chris_99 | i'm guessing 0000 - 9999 | 11:02 |
chris_99 | scary shit right there! | 11:02 |
kanzure | yep | 11:03 |
joepie91_ | it's amazing how I can track the spreading of that link | 11:04 |
joepie91_ | from one channel, to #swhack, to here | 11:04 |
joepie91_ | lol | 11:04 |
kanzure | all things go through irc | 11:05 |
dingo | lol | 11:09 |
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kanzure | antibody stain visualization site thing http://www.visabl.com/ | 11:39 |
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chris_99 | time to try out brlcad, fingers crossed it imports something a bit better than freecad | 12:00 |
kanzure | consider using python-brlcad (there's a bunch of stuff missing, but you can still access the underlying brlcad functions) | 12:00 |
kanzure | yashgaroth: can an antibody stain be made for most proteins? | 12:01 |
chris_99 | what's the difference between that an brlcad? | 12:01 |
yashgaroth | pretty much | 12:02 |
kanzure | you get to use python instead of tcl | 12:02 |
chris_99 | ah ok | 12:02 |
kanzure | yashgaroth: what things am i missing? http://diyhpl.us/wiki/dna/projects/ | 12:02 |
gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=8b92a063 Bryan Bishop: also mention recombinant monoclonal antibodies >> http://diyhpl.us/diyhpluswiki/dna/projects/ | 12:03 |
yashgaroth | biopharmaceuticals in general, though most of them are monoclonals | 12:04 |
kanzure | someone asked me the other day why custom dna is important | 12:05 |
kanzure | ranting about random crops with herbicide resistance is sort of a non-answer | 12:06 |
yashgaroth | I mean it's used every day in research labs, but if you're going for a list of stuff that's been commercialized then it's not bad | 12:06 |
yashgaroth | rant about cancer, people love that | 12:07 |
kanzure | well, with an actual ability to make custom dna, we could be doing other things | 12:07 |
yashgaroth | DNA vaccines, if those ever get off the ground | 12:07 |
yashgaroth | oh and gene therapy stuff in general | 12:08 |
yashgaroth | wait, by "we" do you mean us with a dna synthesizer? | 12:10 |
kanzure | sort of, not specifically us, but including us | 12:10 |
kanzure | with larger plasmids we could proably get entire metabolic pathways from one organism to another | 12:10 |
kanzure | (even if it requires lots of tweaking) | 12:10 |
kanzure | *probably | 12:10 |
yashgaroth | transferring genes between species often requires synthetic DNA to compensate for differences in codon preference | 12:12 |
yashgaroth | but of course that's like 5% of the work involved in making tomatoes generate fish antifreeze protein or whatever | 12:14 |
yashgaroth | I'm not experienced with trying to convince people who have no knowledge of molecular biology on the merits of it, really | 12:16 |
kanzure | a lot of it seems to be "finding really obscure industrial use cases" | 12:16 |
kanzure | "hey there's like 2 oil refineries that could use this enzyme to get a 20000% efficiency boost" "uh...." | 12:17 |
kanzure | on the other end of the spectrum are the sensor/diagnostic people | 12:18 |
yashgaroth | the bulk of | 12:19 |
yashgaroth | whoops hang on | 12:19 |
yashgaroth | bulk of DNA synthesis work, like in terms of total base pairs, is genome synthesis or high-throughput screening for drug discovery | 12:20 |
kanzure | i suppose genome synthesis' big use case is situations where you don't already have that organism laying around | 12:20 |
yashgaroth | or when you'd need to delete a bunch of it | 12:21 |
yashgaroth | delete/modify | 12:21 |
yashgaroth | and screening stuff, while using the same basic principles as gene synthesis, is just 'generate a billion random sequences and do phage display' | 12:22 |
kanzure | right | 12:22 |
yashgaroth | if you have an enzyme from organizm X that would improve organism Y, you identify modifications to make, maybe with a few variants, and have them made | 12:23 |
yashgaroth | then it's making a thousand clones with that gene added, and months to screen for one that it works well in | 12:24 |
yashgaroth | clones as in modified cells or organisms | 12:24 |
yashgaroth | nonetheless I would still like a DNA synthesizer if you clear it with DHS | 12:28 |
kanzure | do you think the current ones are under the jurisdiction of the DHS? | 12:31 |
yashgaroth | it's a very grey area | 12:31 |
yashgaroth | not directly like 'oh we gotta wait for our DHS synthesizer license renewal to come in' | 12:32 |
yashgaroth | I'm trying to think of a good comparison...something vaguely like precursor chemicals maybe | 12:34 |
yashgaroth | mixed with, like, building your own ICBM-compatible GPS circuit | 12:38 |
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kanzure | http://2008.igem.org/Team:Imperial_College "First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography. Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein. Finally, when our bacteria are stationary in the correct location, the biomaterial production is ... | 13:11 |
kanzure | ... triggered. These biomaterials can self-assemble to form a 3D bio-scaffold." | 13:11 |
kanzure | .title https://www.youtube.com/watch?&v=pqEmKkY5DxA | 13:11 |
yoleaux | Biofabricator | 13:11 |
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kanzure | seba--: btw, your local school keeps winning all the igem competitions. you might want to go stalk them. | 13:41 |
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kanzure | http://www.ardeypharm.de/en/ "Nissle 1917 is a commercially available non-pathogenic, probiotic strain of E. coli. It has been successfully used to treat gastrointestinal disorders including colitis and intestinal bowel disease and shows little immunostimulatory activity." | 13:49 |
kanzure | http://2008.igem.org/Team:MIT "Streptococcus mutans, the main cause of dental caries, binds to glycoproteins on the teeth. A clinical study (Kelly CG et al.; Nature Biotechnol. 1999) isolated the 20aa functional segment (p1025) that S.mutans uses to attach to the teeth. p1025 competitively inhibits the binding of S.mutans, causing unharmful bacteria to grow in its place, preventing the recolonization of S.mutans for 90 days. We are ... | 13:54 |
kanzure | ... engineering Lactobacillus bulgaricus, a bacteria commonly found in yogurt, to produce and secrete this peptide under a promoter activated by lactose." | 13:54 |
kanzure | wtf? http://2009.igem.org/Team:Todai-Tokyo "A large part of the world is bitter towards the act of smoking. However, many people like smoking or cannot quit. You might be one of such person. As a solution, what if a noxious smell is emitted from your mouth if you smoke by braking the "non-smoking promise"?? Your breath will stink and all the people around you: professors, friends, family members, and even your boy/girl friend will leave you. ... | 14:05 |
kanzure | ... You will have not choice but to live in isolation...." | 14:05 |
chris_99 | haha, what's' their proposition? | 14:05 |
kanzure | microbe | 14:07 |
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seba-- | kanzure, i know | 14:28 |
kanzure | alright | 14:28 |
seba-- | kanzure, i'm at it | 14:28 |
kanzure | http://2009.igem.org/Team:UCL_London (fluorescent proteins to indicate different types of stress) | 14:32 |
seba-- | kanzure, well my gf will go into a GMO PhD biotech now, so ... lol | 14:39 |
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gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=7210c215 Bryan Bishop: various igem projects >> http://diyhpl.us/diyhpluswiki/dna/projects/ | 15:14 |
AshleyWaffle | hey so brain computer interfaces can mostly just do input right now, right? | 15:18 |
AshleyWaffle | like recieve data | 15:18 |
AshleyWaffle | lets say they could output | 15:18 |
AshleyWaffle | A) do we know which part of the brain holds learning, so that you could feed info for example B) what is the theoretical maximum rate | 15:18 |
chris_99 | have a look a transcranial magnetic stimulation etc. | 15:18 |
chris_99 | *at | 15:18 |
AshleyWaffle | hm | 15:19 |
AshleyWaffle | does it have the level of precision needed for "downloading info" to the brain | 15:19 |
AshleyWaffle | ie books or osmething | 15:19 |
chris_99 | no | 15:19 |
kanzure | yes, but your brain wouldn't understand it | 15:20 |
AshleyWaffle | Ah | 15:20 |
AshleyWaffle | Is there a way to do it in such a way that it would? | 15:20 |
kanzure | Has anyone ever done like which that? | 15:20 |
AshleyWaffle | Perhaps you just need to reverse engineer how the information is encoded that is recieved neurally | 15:20 |
AshleyWaffle | What? | 15:20 |
yashgaroth | maximum theoretical rate is ~1 martial art style/sec, per the matrix | 15:20 |
AshleyWaffle | lol | 15:21 |
AshleyWaffle | and yeah I mean matrix learning | 15:21 |
AshleyWaffle | im interested in it | 15:21 |
AshleyWaffle | I struggle with motivation and other issues, I could just consume all books related to psychology, NLP, and self-help in like 5 minutes or something | 15:21 |
AshleyWaffle | or at least without needing to be motivated to read them lol | 15:21 |
kanzure | there are drugs that can change motivation | 15:21 |
-!- seba-- is now known as seba- | 15:22 | |
kanzure | also deep brain stimulation and other forms of brain damage | 15:22 |
AshleyWaffle | yes but even then my goal would still be accelerated learning | 15:22 |
AshleyWaffle | because self-improving | 15:22 |
AshleyWaffle | is there a theoretical limit on how much someone can know? | 15:22 |
AshleyWaffle | or does the brain have tons of "extra space" | 15:22 |
kanzure | yes, look up thermodynamic limits of superobjects | 15:22 |
seba- | what | 15:23 |
AshleyWaffle | well... the only limits arent just thermodynamic in nature right? lol | 15:23 |
kanzure | there is an information theoretic limit to the amount of information storable per unit of energy/atom | 15:23 |
AshleyWaffle | I mean a non-augmented brain | 15:23 |
kanzure | it is a maximum limit | 15:23 |
kanzure | well, you asked.. | 15:23 |
AshleyWaffle | no, I mean information per human brain | 15:23 |
seba- | lol | 15:23 |
AshleyWaffle | hi seba- | 15:23 |
seba- | hi AshleyWaffle | 15:23 |
kanzure | merkle did an estimation of the information content of the human brain | 15:23 |
AshleyWaffle | content or capacity? | 15:24 |
kanzure | whatever | 15:24 |
AshleyWaffle | mmm | 15:24 |
AshleyWaffle | what is it? | 15:24 |
kanzure | http://www.merkle.com/humanMemory.html | 15:24 |
FourFire | AshleyWaffle, hello! | 15:24 |
seba- | AshleyWaffle, bunga bunga? | 15:24 |
AshleyWaffle | can we get a measurement in books? | 15:24 |
AshleyWaffle | hey FourFire | 15:24 |
seba- | in LoC? | 15:25 |
AshleyWaffle | ? | 15:25 |
FourFire | afaik BCI are input only currently, but you can look into TransCranial Stimulation and LED shining through the skull | 15:25 |
kanzure | ugh, you are all terrible people | 15:25 |
seba- | kanzure, why | 15:25 |
kanzure | how the fuck does electrophysiology work if you can't read neural signals | 15:25 |
kanzure | your understanding of the world is totally inconsistent | 15:25 |
seba- | oh that. | 15:26 |
AshleyWaffle | ??? | 15:26 |
FourFire | AshleyWaffle, I would hazard that with current technology it would be more effective to do some of the more scientifically proven hynosis methods with VR (sight and sound) which is optimized for learning | 15:26 |
kanzure | http://en.wikipedia.org/wiki/Electrophysiology#Extracellular_recording | 15:26 |
seba- | :o | 15:26 |
FourFire | we can't beam knowledge in curcumventing the senses yet | 15:26 |
FourFire | there are some experiments being done in erasing memories in mice, but that's the opposite of what you're asking about | 15:27 |
seba- | just implant a SD card and a brain2ttl converter | 15:27 |
kanzure | http://en.wikipedia.org/wiki/Microelectrode_array | 15:27 |
AshleyWaffle | FourFire: I see, interesting | 15:28 |
FourFire | kanzure, please, don't be so misanthropic, I might not be as great and knowing as you, but I may yet help the cause... | 15:28 |
AshleyWaffle | FourFire: which techniques are proven | 15:28 |
seba- | we should implant into frigid girls an orgasm on demand module | 15:28 |
kanzure | FourFire: just don't say wrong things | 15:28 |
FourFire | AshleyWaffle, the limits aren't brain capacity, they are bandwidth | 15:28 |
kanzure | what | 15:28 |
FourFire | (for the time being, that is) | 15:28 |
AshleyWaffle | kanzure: sometimes people are wrong :/ | 15:28 |
AshleyWaffle | FourFire: also the word you're looking for isn't misanthropic | 15:29 |
seba- | i am | 15:29 |
AshleyWaffle | FourFire: Oh? What's the quickest way to learn | 15:29 |
FourFire | kanzure, I can't not say wrong things without knowing the universal truths, but what I can say are approximations based on my best knowledge, which may or may not be superior to the person i am conversing with | 15:29 |
kanzure | the quickest way to learn is to limit yourself to things that have extremely steep learning curves | 15:29 |
kanzure | FourFire: i have no clue how your "best knowledge" would tell you that electrophysiological recordings are fake.... | 15:30 |
kanzure | seba-: i'd vote in support of orgasmobuttons, pudendal nerve stuff, etc. | 15:30 |
kanzure | seba-: unfortunately, it would work in both females and males, not meeting your frigid girls-only requirement.. | 15:30 |
FourFire | AshleyWaffle, well schools suck, and I am not proven to be skilled at it, but I've found I can learn something which interests me where I absolutely must gather more knowledge in order to think about it in my head | 15:31 |
FourFire | so, yeah steep learning curve, + interest in modeling with the subject in question | 15:31 |
AshleyWaffle | adjusting for learning curves | 15:31 |
seba- | kanzure :-( | 15:31 |
kanzure | seba-: is that really the end of the world haha | 15:31 |
AshleyWaffle | so the curve for everything = X | 15:31 |
AshleyWaffle | what is the quickest way to learn | 15:31 |
seba- | kanzure, imagine porn with orgasmic feedback | 15:32 |
FourFire | kanzure, I didn't say anything whatsoever about electrophysiological recordings | 15:32 |
kanzure | FourFire: you said that brain computer interfaces can't read | 15:32 |
kanzure | FourFire: that they can only stimulate | 15:32 |
kanzure | seba-: i dunno if i can, what would that mean | 15:32 |
AshleyWaffle | please dont fight ;-; | 15:32 |
FourFire | wait what? | 15:32 |
FourFire | I meant the reverse, of course, lol | 15:33 |
AshleyWaffle | FourFire: dont engage :( | 15:33 |
kanzure | FourFire: 15:25 < FourFire> BCI are input only | 15:33 |
AshleyWaffle | kanzure: yeah input from the computers perspective | 15:33 |
AshleyWaffle | now pls no fight | 15:33 |
seba- | kanzure, it's like with sound, or visual, only that you would achieve orgasm at the same time and way as in the porn video | 15:33 |
kanzure | AshleyWaffle: nobody is fighting, relax | 15:33 |
seba- | we could call it 5D porn | 15:33 |
FourFire | they can't stimulate, can only read (unless you mean intrusive, which I don't) | 15:33 |
FourFire | input... from the user... user input | 15:33 |
kanzure | seba-: oh i see, i dunno what the time-to-orgasm is after stimulation of that nerve, might not be a direct relationship | 15:34 |
FourFire | AshleyWaffle, don't worry about us arguing, I understand that a little conversational rustle tustle is a requirement for conversing with kanzure ;) | 15:34 |
seba- | kanzure, what about anal electroshocks, i've heard you ejaculate | 15:34 |
seba- | +that | 15:34 |
kanzure | why do you guys insist that you have to fight me to talk with me | 15:35 |
seba- | i wonder if that's true, if also girls achieve orgasm, by anal electroshocks | 15:35 |
seba- | AshleyWaffle, could you try? | 15:35 |
kanzure | stop calling it fighting | 15:35 |
FourFire | of course, if you're going to be putting electrodes in places withy nerves you can force inputs | 15:35 |
AshleyWaffle | lol | 15:35 |
kanzure | seba-: pudendal nerves work just fine iirc | 15:35 |
AshleyWaffle | kanzure: oh youre a wimminz? :D | 15:35 |
kanzure | .g wimminz | 15:35 |
yoleaux | http://www.urbandictionary.com/define.php?term=wimminz | 15:35 |
kanzure | .ud wimminz | 15:35 |
seba- | kanzure, how do you stimulate it? | 15:36 |
kanzure | .u wimminz | 15:36 |
yoleaux | No characters found | 15:36 |
AshleyWaffle | LOL | 15:36 |
seba- | could you use electricity | 15:36 |
seba- | hm | 15:36 |
FourFire | but I doubt you can pass on *knowledge* except on the order of single bytes that way with current tech | 15:36 |
kanzure | seba-: ultrasound | 15:36 |
kanzure | seba-: ultrasound, electricity, etc | 15:36 |
seba- | oh | 15:36 |
AshleyWaffle | the urban dictionary page is awful | 15:36 |
seba- | how do you do it with ultrasound? | 15:36 |
kanzure | FourFire: knowledge might not exist in any biologically relevant way | 15:36 |
kanzure | seba-: http://diyhpl.us/~bryan/papers2/neuro/ultrasound/ | 15:36 |
FourFire | "w'ere gonna send an SOS, when you're jizzing, that's a dash, when you're dryclenching, that's a dot" | 15:36 |
seba- | oh | 15:36 |
seba- | have you tried it? | 15:37 |
kanzure | nope | 15:37 |
kanzure | but there's bunches of research | 15:37 |
nmz787 | why do android file paths have so many directories in them? | 15:37 |
FourFire | kanzure, your definitions are vague and an attractor to pointless argument. | 15:37 |
FourFire | kanzure, people can write books | 15:37 |
nmz787 | like in compiling projects | 15:37 |
kanzure | FourFire: which definition is vague pls | 15:37 |
FourFire | books contain knowledge | 15:37 |
kanzure | haha no | 15:38 |
FourFire | therefore people can contain AND pass on knowledge | 15:38 |
kanzure | books do not contain knowledge | 15:38 |
seba- | it would be interesting | 15:38 |
seba- | this is the future | 15:38 |
seba- | masturbation devices using this | 15:38 |
kanzure | knowledge is what happens when you read a book and think about the symbols, and then try to reconstruct the meaning the author intended | 15:38 |
gradstudentbot | Wow, very ethical. | 15:38 |
FourFire | aright, books contain patterns which can be decoded using human brains into knowledge, which is stored biologically | 15:38 |
chris_99 | gradstudentbot, get back to research boy! | 15:38 |
gradstudentbot | Does this look contaminated to you? | 15:38 |
seba- | you could make female panties having this inside | 15:38 |
kanzure | it may not be stored biologically at all | 15:38 |
AshleyWaffle | gradstudentbot: whats unethical? | 15:38 |
gradstudentbot | Where did you put my samples? | 15:38 |
seba- | so when they are bored they can just engage it | 15:39 |
kanzure | the human brain is quite lossy at remembering certain things | 15:39 |
nmz787 | its all memes | 15:39 |
AshleyWaffle | are there male panties? | 15:39 |
kanzure | AshleyWaffle: he means the orgasm button may be unethical | 15:39 |
AshleyWaffle | kanzure: thats a pretty disgusting position to hold | 15:39 |
seba- | AshleyWaffle, probably | 15:39 |
FourFire | AshleyWaffle, you're talking about wireheading | 15:39 |
FourFire | which has ethical qualms attached | 15:39 |
seba- | anyway | 15:39 |
kanzure | AshleyWaffle: radstudentbot? yeah, well.. | 15:39 |
AshleyWaffle | FourFire: huh? | 15:40 |
seba- | maybe this nerve gets stimulated | 15:40 |
nmz787 | yo dawg i heard you like knowledge, so i encoded your meme into book, so you can deocde while you reload | 15:40 |
seba- | by anal probes | 15:40 |
AshleyWaffle | uh fuck ethics? | 15:40 |
gradstudentbot | Man, if only I could biopsy his organs. | 15:41 |
FourFire | "why do you guys insist that you have to fight me to talk with me" I don't AshleyWaffle is, I just find it difficult to communicate relatively simple concepts to you, which is annoying since you seem intelligent, just slightly malicious in your (probably not actually deliberate) misunderstanding | 15:42 |
kanzure | maybe your concepts aren't as simple as you've been mislead into thinking | 15:42 |
kanzure | (human) "memory" is extremely weird | 15:42 |
kanzure | and "knowledge" | 15:42 |
seba- | AshleyWaffle is probably working for you | 15:43 |
FourFire | kanzure, ok, how is "knowledge" as you define it, stored or transferred in some way involving brains, which is not biological in nature? | 15:43 |
seba- | how much did you pay her? | 15:43 |
kanzure | working for which one? | 15:43 |
kanzure | FourFire: i'm not sure if i would say it is; i would say that human brains are able to communicate with each other, and then they reconstruct messages and on each end | 15:43 |
seba- | i wonder if anyone has done research on this hm | 15:43 |
seba- | http://www.mmsinternational.com/int/681/gastroenterology-pudendal-nerve-stimulation | 15:44 |
seba- | lol | 15:44 |
FourFire | kanzure, then it's like i said with a pattern being encoded and put into books, which is then decoded inside a brain | 15:44 |
FourFire | and thus *knowledge* has been passed | 15:45 |
kanzure | yeah, but you wouldn't say the knowledge is in the book | 15:45 |
kanzure | like you did | 15:45 |
FourFire | yes, perhaps it's too abstract a concept for you to take seriously | 15:45 |
kanzure | i would say that if knowledge is "communicated" at all, it is by each side of the communication generating it on its own or something, based on their attempts at communication | 15:45 |
seba- | oh | 15:46 |
seba- | there's a word for this | 15:46 |
seba- | electroejaculation | 15:46 |
seba- | lol | 15:46 |
kanzure | seba-: hmm i thought i had a paper or two about this, but i can't find it | 15:46 |
seba- | http://en.wikipedia.org/wiki/Electroejaculation | 15:46 |
FourFire | this damned bandwidth limitation is encouraging me to compress my information transfer into abstractions | 15:46 |
seba- | i wonder if this works on humans | 15:46 |
kanzure | of course it does | 15:46 |
seba- | does it work also on women? | 15:46 |
kanzure | yes | 15:46 |
seba- | nice | 15:46 |
seba- | i must try it | 15:46 |
kanzure | various car injuries have caused damage to this nerve in the past | 15:47 |
FourFire | so instead of saying "I.I.S.A.A.P.I.A.B.A.T.D.I.A.B" I say "knowledge is in books" | 15:47 |
kanzure | now you have a reason to drive even more recklessly | 15:47 |
seba- | Electroejaculation is usually carried out under a general anesthetic. | 15:47 |
seba- | huh | 15:47 |
FourFire | why can i say this to any other person, but not you? | 15:47 |
seba- | why? | 15:47 |
seba- | is it painful? | 15:47 |
kanzure | seba-: depends on their method of stimulation! i imagine that "electrojaculation" might just be "electroshock" without specifically targetting a certain nerve. | 15:47 |
kanzure | FourFire: because i am not okay bullshitting you | 15:48 |
kanzure | FourFire: unless i am trolling you on purpose | 15:48 |
kanzure | in which case, sky's the limit | 15:48 |
gradstudentbot | Is that published? | 15:49 |
seba- | http://en.wikipedia.org/wiki/Erotic_electrostimulation | 15:49 |
seba- | lol | 15:49 |
seba- | wtf | 15:49 |
seba- | http://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Electric_Stimulation.jpg/800px-Electric_Stimulation.jpg | 15:49 |
FourFire | fine, so the brains don't ever contain knowledge... | 15:49 |
seba- | lol | 15:49 |
jrayhawk_ | transhumanism.jpg | 15:50 |
FourFire | they just contain the biological-alphabet equivalent to a decoder that can parse PI into any arbitrary information | 15:50 |
FourFire | and books contain alphabet PI | 15:50 |
kanzure | haha yeah right, | 15:50 |
gradstudentbot | I punched my PI and that's why I work here now :\ | 15:50 |
kanzure | you can show people the same book and not everyone will extract the same information | 15:50 |
nmz787 | PI? Private Investigator? | 15:51 |
FourFire | books contain alphabet PI, kanzure, and humans can write alphabet PI into books, therefore the information which can be decoded from alphabet PI is being transferred somehow! | 15:51 |
kanzure | principal investogator :p | 15:51 |
kanzure | FourFire: how did this turn into information? i thought you said knowledge | 15:51 |
nmz787 | re the non gradstudentbot comments? | 15:51 |
gradstudentbot | I have to read all these articles. | 15:51 |
nmz787 | alphabet principal investigator? | 15:51 |
kanzure | hrm | 15:52 |
kanzure | good point | 15:52 |
nmz787 | a prof that studies language? | 15:52 |
FourFire | so when you say " knowledge might not exist in any biologically relevant way" how does it even have meaning? | 15:52 |
FourFire | this is what I mean by your definitions being vague and an attractor to pointless argument | 15:52 |
kanzure | it means "folk psychology often encroaches far beyond the theoretical studies' results" | 15:53 |
kanzure | "folk psychology is not necessarily going to lead to results where your understanding of how the brain operates happens to map to reality" | 15:53 |
seba- | Something went haywire with his balls, and before a procedure to fix the damage a brisk military nurse hooked him up to a device without explaining what she was doing. It wasn't a rectal deal like this thing, more like adhesive pads hooked to a box. | 15:53 |
seba- | Nurse Ratched grabbed his dong with a specimen cup in hand and hit the switch. He described the orgasm as mind blowing. With a grin from ear to ear he asked where he could purchase one of the devices. | 15:53 |
seba- | hm | 15:53 |
FourFire | kanzure, because your were purpoisely being obtuse in such a way that i can only suspect you wanted me to completely redefine whatever you're waving as "knowledge" into something I can actually use to talk to you about | 15:54 |
FourFire | you* | 15:54 |
kanzure | FourFire: look, if you want "matrix-style learning", you will first have to investigate whether or not it is possible, not just make up whatever definitions you want | 15:54 |
kanzure | reality owes you nothing | 15:54 |
kanzure | it will not just happen to map directly to notions of memory that turn out to be physically implausible | 15:54 |
FourFire | please explain "knowledge might not exist in any biologically relevant way" in different words | 15:54 |
kanzure | 15:52 < kanzure> it means "folk psychology often encroaches far beyond the theoretical studies' results" | 15:55 |
FourFire | ok | 15:55 |
nmz787 | seba-: for cattle i read they use fake cows, which they get the bull to mount... i wonder if they use the method you mention too | 15:55 |
seba- | nmz787 they do | 15:55 |
kanzure | what? really? | 15:55 |
nmz787 | it might freak the bull out | 15:55 |
seba- | but i'm wondering if it's used in males | 15:55 |
seba- | human ones | 15:55 |
nmz787 | he would be an o'organic' bull anymore maybe :P | 15:55 |
nmz787 | they o in o' was a typo | 15:56 |
FourFire | I agree that different people can get different "knowledge" out of the same book | 15:56 |
gradstudentbot | My code works. I have no idea why... | 15:56 |
nmz787 | FourFire: that's the whole idea of stenography | 15:56 |
nmz787 | the decoder matters | 15:57 |
nmz787 | same thing with an SD card and a computer | 15:57 |
FourFire | there is no way that information exists in brains in anywhere near something like it does in computers and other nonbiological information storage systems | 15:57 |
nmz787 | if the deocoder doesn;t work, blah, garbage | 15:57 |
nmz787 | same in DNA with frameshifts | 15:57 |
nmz787 | as they say in thailan, 'its same same' | 15:57 |
FourFire | nmz787, in this case I mean something with no "hidden messages" but sure | 15:57 |
nmz787 | or chemical reaction ordering | 15:58 |
nmz787 | it matters | 15:58 |
nmz787 | or the end result differs | 15:58 |
seba- | nmz787, https://www.youtube.com/watch?v=TmZ19Sxab_4 | 15:58 |
FourFire | did we scare AshleyWaffle off? | 15:58 |
kanzure | nmz787: someone asked me about "useful projects that could be done if whole genome synthesis was a few million times cheaper", http://diyhpl.us/wiki/dna/projects/ am i missing anything obvious? | 15:58 |
nmz787 | kanzure: yea, more drugs... artemisinin, etc... | 16:01 |
seba- | kanzure you also watch it | 16:01 |
seba- | it's interesting | 16:01 |
kanzure | seba-: http://www.psas.nl/artikelen/TENS.pdf | 16:01 |
kanzure | seba-: there are others but i don't remember them at the moment | 16:02 |
seba- | i wonder if it works on females | 16:02 |
kanzure | .title https://www.youtube.com/watch?v=TmZ19Sxab_4 | 16:02 |
yoleaux | bull electroejac | 16:02 |
FourFire | AshleyWaffle, the thing is, that I was about to explain to you, that we know oursenses can pass on information into our brains, but we honestly have no idea what nerve signal encoding protocols exist and which to use in the case of directly stimulating nerves, so when I say "I doubt you could pass on *knowledge* past some bytes, I mean you might be able to induce pavlovian responses or something like that, but nothing more until we | 16:02 |
FourFire | learn more about how info goes around the body | 16:02 |
kanzure | nmz787: well, drugs are kinda obvious i guess, but i'm looking for other things | 16:02 |
kanzure | nmz787: i know i've seen all sorts of magical transgenic things in the past, but i wasn't keeping a list | 16:03 |
kanzure | this one was pretty clever- "treat allergic rhinitis by engineering Staphylococcus epidermidis, a microbe endogenous to the human nasal flora, to secrete a recombinant histamine-binding protein in response to the elevated histamine concentrations of an allergic response" | 16:03 |
FourFire | AshleyWaffle, so, like I said, the most effective method of learning with current tech might be VR + hypontism + optimized lessons/video/gamelevel scenarios for teaching you whatever skill | 16:03 |
nmz787 | kanzure: i don't think anything is obvious to uneducated people | 16:03 |
FourFire | nothing like in the matrix | 16:03 |
seba- | kanzure but this stopped orgasm, i want the opposite | 16:03 |
kanzure | FourFire: you know people actually study learning, and i'm pretty sure hypnotism is not the method that comes out on top | 16:04 |
kanzure | seba-: yeah, it goes both ways depending on type of stimulation, iirc | 16:04 |
seba- | oh | 16:04 |
kanzure | seba-: the hackerspace in prague built a device to do it | 16:04 |
kanzure | pasky: do you remember the name of the brmlab orgasmotron | 16:04 |
seba- | really | 16:04 |
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seba- | why do they use it for | 16:04 |
kanzure | i think pasky might know | 16:04 |
FourFire | kanzure, well I don't know if you'd classify causing people to be in a mental state which facilitates learning as hypnotism | 16:05 |
seba- | watch the video, then google terrorist stuff, then watch more cow semen collection videos. repeat this for 8 hours then some guy at the nsa will have to watch the bull semen videos over and over while analyzing them for codes and secret messages. | 16:05 |
seba- | ahahahhaha | 16:05 |
FourFire | you could do that with trained cues, or controlled environmental factors, not that I know what those are | 16:05 |
kanzure | seba-: only funny if they don't like it | 16:05 |
FourFire | seba-, lel | 16:05 |
FourFire | because of people like you seba- there's some people with weird boners working at the NSA | 16:06 |
kanzure | yeah, like people who like math | 16:06 |
kanzure | sickos | 16:06 |
nmz787 | i doubt neural codings are standardized within the species | 16:07 |
kanzure | oh i didn't mean a specific neural ensemble encoding | 16:07 |
seba- | http://commons.wikimedia.org/wiki/File:Electroejaculation.jpg | 16:07 |
seba- | lol | 16:07 |
seba- | wikipedia has everything | 16:07 |
FourFire | kanzure, I hope to use the last one on your list someay | 16:08 |
FourFire | someday* | 16:08 |
kanzure | my sarcastic comment about math? | 16:09 |
FourFire | no, sorry "DNA vaccines" | 16:09 |
kanzure | it's obviously referring to the fact that the nsa has a weird balance between math for defense and math for offense | 16:09 |
FourFire | i's been done already, but what if you could do that on a person by person basis | 16:09 |
FourFire | 1$ to map a genome and then output an active retrovirus containing a "perfect" variant of their genome with all the broken disease alleles replaced with nice working ones | 16:11 |
FourFire | jab them , get them to stay indoors for a week... | 16:11 |
FourFire | but then you've got to be realistic about these things, this type of technology won't exist for many decades | 16:12 |
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kanzure | yeah, retroviruses don't exist | 16:13 |
kanzure | duh | 16:13 |
kanzure | wtf is his problem? | 16:13 |
seba- | Volts are slowly increased until a man ejaculates. The majority of men are able to ejaculate in under 20 volts. | 16:14 |
seba- | lol | 16:14 |
seba- | this is funny | 16:14 |
seba- | under 20 volts | 16:14 |
seba- | haha | 16:14 |
kanzure | it's pretty common | 16:15 |
kanzure | i mean, it's depicted in the media often | 16:15 |
kanzure | sold in stores, etc | 16:15 |
seba- | bizzare | 16:17 |
kanzure | remind me to never take you to a livestock store | 16:19 |
seba- | Out of curiosity I took one of the pads from just above my knee and placed it on the under side of the head of my penis. OMG!!! Within 5 minutes I reached an ejaculation that was unbelievable. | 16:20 |
seba- | lol | 16:20 |
seba- | but this is not ok 5 min, i thought it's instantaneous | 16:20 |
jrayhawk_ | no, man, you have to take it slow with your pelvic floor. take it to a movie, buy it flowers... | 16:21 |
jrayhawk_ | you don't want to scare it off! | 16:21 |
seba- | this is bizzare | 16:23 |
seba- | i wonder if it really works, i can't find a human video | 16:24 |
seba- | lol | 16:24 |
jrayhawk_ | well, you have to pay for those | 16:24 |
seba- | hm | 16:25 |
seba- | i guess it should work | 16:26 |
seba- | why not | 16:26 |
seba- | i just never thought about it | 16:26 |
seba- | until today | 16:26 |
seba- | lol | 16:26 |
kanzure | it is very clear that you never dated anyone with an electricity kink | 16:26 |
seba- | of course i didn't lol | 16:27 |
seba- | anyway, i still don't get how you can use pulses to stimulate and destimulate | 16:27 |
seba- | how does that work?! | 16:27 |
kanzure | membrane potential stuff | 16:27 |
seba- | yes but is it frequency (waveform) or just amplitude (voltage/current) ? | 16:29 |
seba- | hm | 16:33 |
seba- | apparently DC works better | 16:33 |
seba- | one guy said he achieved with DC a 2 min orgasm | 16:33 |
seba- | interesting | 16:33 |
seba- | oh | 16:34 |
seba- | he inserts the probe | 16:34 |
seba- | directly in his prostate | 16:34 |
seba- | lulz | 16:34 |
seba- | wtf | 16:34 |
seba- | these people are crazy | 16:34 |
seba- | kanzure, so do you know a girl with such kinks? | 16:47 |
kanzure | hmm | 16:54 |
kanzure | maybe | 16:54 |
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seba- | http://www.google.com/patents/US3941136 | 17:00 |
kanzure | .title | 17:00 |
yoleaux | Method for artificially inducing urination, defecation, or sexual excitation | 17:00 |
seba- | but it doesn't state anything about ejaculation | 17:07 |
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jrayhawk_ | experimentation with electrostimulation is somewhat common in the BDSM scene, though a large portion of that is just for pain's sake | 17:29 |
seba- | jrayhawk_, it seems very interesting | 17:30 |
seba- | jrayhawk_, you should do some research | 17:30 |
seba- | i'm interested in some things | 17:30 |
jrayhawk_ | the extreme body mod scene had a lot more dedication to electrojaculation | 17:31 |
seba- | jrayhawk_, that patent talks only about erection | 17:31 |
seba- | i'm wondering if you keep at 20 V if you ejaculate | 17:31 |
seba- | can you try? | 17:31 |
kanzure | i doubt that people in "the BDSM scene" care about patents | 17:31 |
seba- | it's a bit different position | 17:32 |
seba- | of electrodes | 17:32 |
seba- | than the BDSM scene | 17:32 |
seba- | i wonder what happens | 17:32 |
seba- | apparently 30 V make you shit yourself | 17:32 |
jrayhawk_ | "17:32 < seba-> can you try?" my expertise comes exclusively from exposure to videos from http://en.wikipedia.org/wiki/Shock_sites | 17:33 |
jrayhawk_ | i do not actually have particular interest or opportunity to try anything | 17:34 |
seba- | oh :( | 17:35 |
seba- | jrayhawk_ i thought you have this at home | 17:35 |
kanzure | because he said two things? | 17:36 |
seba- | kanzure yes | 17:36 |
jrayhawk_ | nope, but the BME community can probably help you out. | 17:36 |
jrayhawk_ | http://wiki.bme.com/index.php?title=Electrical_Play | 17:37 |
jrayhawk_ | I think a lot of their content, including the "Extreme" section,\ is paywalled. | 17:38 |
kanzure | "too extreme for the internet at large" | 17:39 |
* kanzure shakes his head | 17:39 | |
kanzure | you know, there used to be a time when i couldn't go a day without being tricked into viewing yet another shock site | 17:39 |
kanzure | times'a changing | 17:40 |
jrayhawk_ | I am sure the BME Pain Olympics figured heavily into those shock sites. | 17:40 |
kanzure | it seems like cheating if all the content was from a single source | 17:40 |
jrayhawk_ | oh, and their forums, apparently | 17:44 |
jrayhawk_ | i guess that makes sense. | 17:44 |
seba- | kanzure is your girlfriend on irc | 17:45 |
seba- | so that she can try this | 17:45 |
seba- | or ex gf | 17:45 |
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kanzure | i don't think any of my girlfriends were ever into electroanything | 17:47 |
kanzure | (or me for that matter) | 17:47 |
seba- | oh | 17:47 |
nmz787 | they weren't into thinking? or their heart beating? | 17:48 |
kanzure | yeah, fuck hearts | 17:48 |
kanzure | wait what? | 17:48 |
pasky | kanzure: multistim | 17:48 |
kanzure | ahh multistim heh | 17:48 |
kanzure | what did it do again? | 17:48 |
nmz787 | "kanzure, sorry, I'm not into electrical-potential gradients" | 17:48 |
kanzure | nmz787: "i am not into carbon-based lifeforms either" | 17:49 |
nmz787 | "i'm not into gradients" | 17:49 |
pasky | hmm it had pressure regulators, electrodes, and maybe some other... output devices | 17:49 |
pasky | they couldn't sell enough of them for the pricetag (about 1500USD), they plan to do a cheaper version sometime in the future | 17:50 |
kanzure | "couldn't sell enough of them" is sometimes used as a euphemism for "they were selling too quickly" | 17:50 |
kanzure | and the literal meaning is "they couldn't sell any" | 17:51 |
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seba- | pasky, so have you tried this http://www.google.com/patents/US3941136 | 17:53 |
seba- | can you shit yourself? | 17:53 |
seba- | it says you can achieve erection by 20 V and then 10 V | 17:53 |
seba- | if you keep at 20 V, do you orgasm? | 17:54 |
seba- | can you try? | 17:54 |
seba- | also it doesn't say if you need a higher voltage for shitting or for urinating | 17:54 |
seba- | can you please try? | 17:54 |
kanzure | why do you think everyone has tried this stuff | 18:01 |
kanzure | pasky is just someone i know that goes to a hackerspace sometimes | 18:01 |
kanzure | and that hackerspace has a machine some other people built | 18:01 |
seba- | so he has access to this | 18:01 |
gradstudentbot | Can I get my own desk? | 18:01 |
kanzure | "I worked on the firmware for the "Applied Biosystems ABI Prism 310 DNA Sequencer"." https://news.ycombinator.com/item?id=7893423 | 18:01 |
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nell | im almost done reading the transhumanist reader | 18:04 |
kanzure | ouch | 18:04 |
kanzure | how bad is it | 18:04 |
nell | It's bearable | 18:04 |
kanzure | really? | 18:04 |
nell | Natasha is a hottie | 18:04 |
kanzure | that makes it bearable? | 18:05 |
nell | lol | 18:05 |
nell | I got Natasha's email to try and spin something together with transhumanism & the maker movement. | 18:07 |
nell | also does anyone here program lisp | 18:07 |
kanzure | there's a few lispers | 18:11 |
kanzure | what do you mean "spin".. do you mean "write an article for hplusmagazine"? :( | 18:11 |
nell | Wow.. Awesome, I never knew about it | 18:13 |
kanzure | never knew about lisp? | 18:13 |
nell | hplusmagazine | 18:13 |
nell | I usually follow kurzweilai and singularityhub | 18:13 |
kanzure | i regret telling you about it | 18:13 |
kanzure | oh man those two are pretty bad too | 18:13 |
kanzure | why do you read these | 18:13 |
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nell | I don't really read, it's candy for my brain in the morning | 18:14 |
kanzure | i see | 18:14 |
kanzure | well, as long as you recognize it's just infotainment | 18:14 |
gradstudentbot | Yeah, it's definitely impractical and fairly non-elegant at the same time. | 18:14 |
nell | infotainment, I'm very glad this has entered my vocabulary | 18:15 |
nell | I gotta get back to scheme | 18:15 |
nell | ciao | 18:15 |
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kanzure | i think this person was last around 2012-09-25 | 18:15 |
yashgaroth | ah yes 21:18 < yashgaroth> shut the fuck up alusion | 18:18 |
kanzure | lovely | 18:19 |
kanzure | http://www.wired.com/wp-content/uploads/2014/05/PowerRangers.jpg | 18:19 |
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nmz787 | http://karenkilgariff.bandcamp.com/track/look-at-your-phone | 18:55 |
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eudoxia | i was too late to catch the lisper | 19:22 |
eudoxia | i'm losing my edge | 19:22 |
kanzure | you can still rewrite nanoengineer for gene_hacker | 19:44 |
catern | eudoxia: what were you going to do with him if you caught him | 19:44 |
eudoxia | catern: do i look like a guy with a plan? you know what i am? i'm a dog chasing cars. i wouldn't know what to do with one if i caught it! the mob has plans. the cops have plans. people who use haskell have plans. you know, they're schemers. that's why scheme is called scheme. schemers trying to control their little worlds. | 19:50 |
kanzure | "Needle complex of Salmonella typhimurium" http://2010.igem.org/wiki/images/8/8c/HokkaidoU_Japan_Fig1.jpg | 19:57 |
kanzure | now that is nanotechnology | 19:57 |
kanzure | "Its length is about 80nm and the diameter of its needle channel is about 2nm." | 19:58 |
eudoxia | it looks like one of those spinny merkle/freitas things that would never work irl | 19:58 |
kanzure | http://2010.igem.org/Team:HokkaidoU_Japan/Projects | 19:59 |
kanzure | http://2010.igem.org/File:HokkaidoU_Japan_Fig6.jpg | 20:02 |
kanzure | http://en.wikipedia.org/wiki/Type_three_secretion_system | 20:03 |
kanzure | "The ability of intracellular bacteria to migrate between host cells." | 20:05 |
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kanzure | microfluidic flow generator by coating microcapillaries with bacteria http://2010.igem.org/Team:SDU-Denmark/project-i | 20:43 |
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kanzure | 3d printing material (light-induced cell lysis release of polyhydroxybutyrate plastic) http://2010.igem.org/Team:Caltech | 20:59 |
gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=aa1333e5 Bryan Bishop: igem projects from 2010 >> http://diyhpl.us/diyhpluswiki/dna/projects/ | 21:11 |
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kanzure | what http://2011.igem.org/Team:Kyoto "We created new E.coli which hunts and eats insects. As such we named it Carnivorous E.coli. Carnivorous E.coli emits light when it is hungry. This will attract insects to it. Then, it secretes a viscous substance to capture the insects. The captured insects are digested by the chitinase in the secretion. Long story short, our Carnivorous E.coli can hunt." | 21:54 |
kanzure | http://2011.igem.org/Team:NYMU-Taipei "To achieve this goal, we use a species of magnetic bacterium, Magnetospirillum magneticum AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we have utilized three genes to achieve neurosymbiosis within ... | 22:09 |
kanzure | ... glial cells: MinC, a division inhibitor, INV, a gene for invasion and LLO, a gene for facilitating escapes from phagosomes." | 22:09 |
kanzure | "A pilus is typically 6 to 7 nm in diameter. During conjugation, a pilus emerging from donor bacterium ensnares the recipient bacterium, draws it in close, and eventually triggers the formation of a mating bridge, which establishes direct contact and the formation of a controlled pore that allows transfer of DNA from the donor to the recipient. Typically, the DNA transferred consists of the genes required to make and transfer pili (often ... | 22:17 |
kanzure | ... encoded on a plasmid), and so is a kind of selfish DNA; however, other pieces of DNA are often co-transferred and this can result in dissemination of genetic traits, such as antibiotic resistance, among a bacterial population. Not all bacteria can make conjugative pili, but conjugation can occur between bacteria of different species." | 22:17 |
kanzure | huh, i didn't know they had a 7 nm diameter | 22:17 |
gradstudentbot | You know, I hear you make more money being a garbage man. | 22:19 |
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kanzure | reflectin thin films http://2011.igem.org/Team:Cambridge#/Project/Microscopy "This animation is composed of layers taken as the microscope was focused through the layers of a sample of reflective squid cells from the eye cup mounted in Phosphate buffered saline" | 22:35 |
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kanzure | more on that syringe protein http://2011.igem.org/Team:HokkaidoU_Japan | 23:31 |
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gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=062e285e Bryan Bishop: igem projects from 2011 >> http://diyhpl.us/diyhpluswiki/dna/projects/ | 23:52 |
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