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| ebowden_ | paperbot: http://informahealthcare.com/doi/pdf/10.3109/00207454.2011.558225 | 00:22 |
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| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/2207cd66b3974d7def59792ca1fa02f3.txt | 00:22 |
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| ebowden_ | :( | 00:23 |
| ebowden_ | paperbot: http://informahealthcare.com/doi/abs/10.3109/00207454.2011.558225 | 00:23 |
| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/ffac3725b7c1233908f8b7d261e8513c.txt | 00:23 |
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| kanzure | hm | 08:01 |
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| kanzure | http://www.techtimes.com/articles/10272/20140711/senators-ask-gilead-sciences-to-explain-itself-high-cost-of-hep-c-drug.htm | 08:18 |
| kanzure | ParahSailin: it's too bad that these companies are on their game re: coverups and settlements for people that die without access to their drugs. otherwise a blackmarket alternative could easily kick up some media storm. | 08:19 |
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| streety | It's interesting that the price is almost exactly the number of people expected to be cured of hepatitis C during the coming year due to this drug | 10:21 |
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| ParahSailin | kanzure: you think there is a coverup conspiracy? | 10:51 |
| kanzure | not a conspiracy, but they are obviously settling with patients' families that die due to non-treatment | 10:53 |
| kanzure | isn't it just a little suspicious that there's never anything in the news about it | 10:53 |
| kanzure | stuff like http://www.dailymail.co.uk/health/article-544112/Lung-patients-condemned-death-NHS-withdraws-expensive-drugs.html | 10:55 |
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| ParahSailin | kanzure: not saying you're wrong, but absence of evidence... | 11:03 |
| ParahSailin | you probably hear more of it in countries with monopsony medicine | 11:04 |
| ParahSailin | that might actually be the market | 11:04 |
| kanzure | ah, like http://www.petertatchell.net/aids/drugprofits.htm | 11:04 |
| kanzure | it's actually a little peculiar | 11:05 |
| kanzure | if people are complaining the drugs are too expensive, why aren't there lots of articles about "my son timmy died because i couldn't pay $30,000/month"? | 11:06 |
| kanzure | i suppose nobody wants to admit it was their own lack of money that killed their kid | 11:06 |
| kanzure | ooh http://www.mamamia.com.au/news/bianca-scott-soliris/ | 11:08 |
| kanzure | "We have created a petition to lobby the government to fund this drug as part of the Australia’s Life Saving Drugs Program. This is a program that funds expensive drugs for people with extremely rare illnesses." | 11:09 |
| kanzure | ok great, so while they are busy reviewing the petition, death | 11:09 |
| kanzure | http://www.gofundme.com/biancas-battle | 11:11 |
| streety | I'm not sure I follow your line of reasoning . . . if I'm a house builder or a landlord and a homeless person dies on the street, am I liable for their death? | 11:11 |
| kanzure | huh? | 11:11 |
| kanzure | no, i'm using their death as a marketing ploy | 11:12 |
| kanzure | for cheap pirate drugs | 11:12 |
| streety | ah right, in that context your comments make more sense | 11:12 |
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| archels | kanzure: with this much money involved, one does begin to wonder why there isn't a larger dark market for these | 11:39 |
| archels | or perhaps there is, and the internet just hasn't discovered it yet? | 11:39 |
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| kanzure | well the total number of under-served patients globally is probably low per each drug | 11:51 |
| kanzure | but probably enough for a single small operation to make money on it | 11:51 |
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| archels | so there have to be organisations that provide these services | 11:53 |
| archels | in a clandestine manner | 11:53 |
| kanzure | why? | 11:54 |
| kanzure | you mean there should be, or there already are? | 12:02 |
| archels | it depends on the ease with which these drugs can be reproduced | 12:12 |
| archels | for example, "Eculizumab (INN and USAN; trade name Soliris) is a humanized monoclonal antibody that is a first-in-class terminal complement inhibitor" | 12:12 |
| archels | how straightforward is it to create these monoclonal antibodies? | 12:12 |
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| kanzure | a monoclonal antibody? well it's not $100k worth of work | 12:18 |
| kanzure | if you were to go get some grad students to write up a bid, it'd come in under $100k | 12:19 |
| cluckj | get gradstudentbot on it | 12:19 |
| archels | http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2189015/summary.html#Details | 12:22 |
| kanzure | .title | 12:22 |
| yoleaux | 2189015 | 12:22 |
| archels | it's the Canadian patent database | 12:23 |
| archels | hm same thing https://www.google.nl/patents/US6355245 | 12:27 |
| kanzure | not surprising | 12:33 |
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| streety | For a single course it might come to $100k due to setup costs (equipment etc). The variable costs would be much lower | 13:43 |
| kanzure | entirely possible. | 13:44 |
| kanzure | also i'm sure you can always find ways to increase costs, like purchasing overpriced equipment. | 13:45 |
| streety | indeed | 13:46 |
| streety | there is a minimal set of checks needed before injecting something though | 13:46 |
| streety | although that is going to be variable depending on desperation | 13:46 |
| kanzure | animals | 13:51 |
| streety | what about them? | 13:55 |
| kanzure | "set of checks". | 14:02 |
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| streety | That wasn't actually what I was thinking about. If you're trying to copy an existing therapeutic I would aim to establish that what you have is what you were trying to copy. I don't think you need to show that it works and/or is non-toxic in an animal | 14:17 |
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| -!- FourFire [~fourfire@181-128-212.connect.netcom.no] has joined ##hplusroadmap | 23:46 | |
| -!- EnLilaSko [EnLilaSko@unaffiliated/enlilasko] has joined ##hplusroadmap | 23:53 | |
| --- Log closed Sun Jul 13 00:00:02 2014 | ||
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