| --- Log opened Sun Jan 04 00:00:13 2015 | ||
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| archels | kanzure: the mention of cybernetics in that HN comment thread is interesting | 03:46 |
|---|---|---|
| archels | (the one on biology needing a Grothendieck or Hilbert) | 03:46 |
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| Qfwfq | augur_: I'd be interested in reading the Haskell side of Language-Engine should you ever release it. | 03:52 |
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| kanzure | archels: fenn lived with that guy for a while | 08:11 |
| kanzure | fenn: what about paid bounties on certain torrents to encourage offline seeders to show up again? | 08:19 |
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| kanzure | .to delinquentme "There is also an American deathgrind band named Hatebeak with a 21 year old African grey parrot named Waldo on vocals." https://www.youtube.com/watch?v=PYeximOhaUk | 10:09 |
| yoleaux | kanzure: I'll pass your message to delinquentme. | 10:09 |
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| kanzure | hi eudoxia | 10:34 |
| eudoxia | kanzure: happy birthday to you :> | 10:34 |
| eudoxia | a whole quarter of a century already | 10:34 |
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| TMA | quarter of a century... so young | 10:42 |
| TMA | kanzure: let me wish you a happy birthday, even though we've never met | 10:43 |
| kanzure | you guys are weird | 10:43 |
| * TMA (still) vividly remembers what it felt like when TMA was only a quarter of a century old. there was no need for nootropics, the brain was fresh and fast even without them | 10:46 | |
| eudoxia | kanzure: what's up? | 10:46 |
| augur_ | Qfwfq: good to know! :) | 10:48 |
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| jrayhawk_ | kanzure will always be, like, twelve in our hearts | 12:08 |
| kanzure | cannibalism, is it? | 12:10 |
| AmbulatoryCortex | eat the flesh of the young to gain their youth, and all that | 12:15 |
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| kanzure | delinquentme: just got a call from my sister that she's up in santa clara, do you do redwood tours? | 12:25 |
| delinquentme | Do you mean like give tours? | 12:29 |
| yoleaux | 18:09Z <kanzure> delinquentme: "There is also an American deathgrind band named Hatebeak with a 21 year old African grey parrot named Waldo on vocals." https://www.youtube.com/watch?v=PYeximOhaUk | 12:29 |
| delinquentme | ROFL kanzure <3 | 12:29 |
| delinquentme | I don't know redwood very well | 12:29 |
| delinquentme | but SF is possible | 12:29 |
| delinquentme | I am also incredibly low on funds at the moment till I start getting paychex | 12:30 |
| kanzure | btw when did they say you're starting? | 12:30 |
| delinquentme | havnt gotten a date yet | 12:31 |
| kanzure | did you get an offer letter? | 12:31 |
| delinquentme | nope only a over-the-phone "yes" | 12:31 |
| kanzure | messed up | 12:31 |
| delinquentme | paperwork is being pushed through starting monday I was told? | 12:31 |
| delinquentme | explain | 12:31 |
| kanzure | nah i mean usually companies are more prompt about this sort of thing, whatever | 12:32 |
| delinquentme | I should have gotten a paper-formatted notification? | 12:32 |
| kanzure | well, email with pdf attachment that you sign | 12:32 |
| delinquentme | its certainly 'harder' but I feel right | 12:32 |
| delinquentme | right = alright * | 12:32 |
| poppingtonic | rofl Hatebeak with a cackling parrot. | 12:34 |
| delinquentme | but yah if your sis is around i'd hangout / grab a coffee and tell her to work on life extension | 12:35 |
| kanzure | .wik ERCC1 | 12:37 |
| yoleaux | "DNA excision repair protein ERCC-1 is a protein that in humans is encoded by the ERCC1 gene." — http://en.wikipedia.org/wiki/ERCC1 | 12:37 |
| kanzure | .wik PCNA | 12:37 |
| yoleaux | "Proliferating cell nuclear antigen (PCNA) is a DNA clamp that acts as a processivity factor for DNA polymerase δ in eukaryotic cells and is essential for replication." — http://en.wikipedia.org/wiki/PCNA | 12:37 |
| kanzure | "Magalhaes is now seeking funding for a project that will insert the whales' genes into mice to see if that improves their resistance to disease" | 12:38 |
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| delinquentme | http://gen.lib.rus.ec/ | 13:56 |
| delinquentme | ^ libgen mirror | 13:56 |
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| delinquentme | One of the great things (I guess if you're a Unix geek) about Graphite is that it also comes with a CLI. ... To access the CLI, simple point your browser at http://yourgraphiteinstall/cli or just click the link on the top of the regular composer window. You will be presented with a prompt like this: | 15:08 |
| delinquentme | wat. | 15:08 |
| catern | ahahahhaha | 15:09 |
| catern | web dev logic | 15:09 |
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| nmz787 | .tell genehacker check out more detailed info here: https://github.com/nmz787/microfluidic-cad/ and nmz787.github.io/html/microfluidics_cad.html | 15:22 |
| yoleaux | nmz787: I'll pass your message to genehacker. | 15:22 |
| nmz787 | .wik Vapor phase reflow | 15:30 |
| yoleaux | "A reflow oven is a machine used primarily for reflow soldering of surface mount electronic components to printed circuit boards (PCB)." — http://en.wikipedia.org/wiki/Reflow_oven | 15:30 |
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| nmz787 | hmm, $2750 for an SEM and EDX detector (needs work) 2 weeks ago in Seattle | 15:49 |
| kanzure | SEM needs work? | 15:51 |
| nmz787 | probably power realted | 15:52 |
| nmz787 | puming station one had something like that, ended up a power supply just needed switched from 240V input to 120V input | 15:53 |
| nmz787 | UK to US power grid | 15:53 |
| nmz787 | though needs work would only really be OK if the system came with manuals | 15:53 |
| nmz787 | I've read the FIB manuals a bit (there is a whole 4 ft shelf worth of those 2 inch thick binders from school) | 15:54 |
| nmz787 | they actually have some schematics | 15:54 |
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| nmz787 | kanzure: start of what looks to be where this example does intersection (I want to add and connect a bend to that channel I made) https://github.com/nmz787/verb/blob/master/example/threeMeshIntersectExample.html#L397 | 15:58 |
| nmz787 | in this example, though, they use THREE to tesselate, while here I guese they push that elsewhere (lightgl maybe?) https://github.com/nmz787/verb/blob/master/example/geometry.html | 16:00 |
| kanzure | https://github.com/pboyer/verb/blob/803e560d0decd21e8c36e6ccf68408860ddbf43f/src/eval/intersect.js#L1122 | 16:00 |
| kanzure | this is mesh intersection and not nurbs intersection | 16:01 |
| kanzure | although intersect_rational_surface_surface_by_aabb_refine might be nurbs | 16:02 |
| kanzure | hmm intersect_rational_surface_surface_by_aabb_refine also does tessellation, so nope | 16:02 |
| nmz787 | hmm, so, it's less mathy and more iterative? | 16:03 |
| nmz787 | err, more discretized? | 16:04 |
| nmz787 | i mean doing the intersection on the meshes | 16:05 |
| nmz787 | rather than intersecting and coming out with new control points and/or knots, etc | 16:05 |
| nmz787 | so doing it on meshes means less performance? | 16:06 |
| nmz787 | does anything else do NURBS intersection? brl? | 16:06 |
| nmz787 | "while we can raytrace them we are still developing the ability to perform operations such as subtraction and intersection between two solid NURBS Boundary Representations " | 16:07 |
| nmz787 | .title http://brlcad.org/wiki/NURBS_Intersections | 16:07 |
| yoleaux | NURBS Booleans - BRL-CAD | 16:07 |
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| kanzure | that wiki page is probably out of date, check last modified time | 16:09 |
| kanzure | in 2012 and 2013 they implemented nurbs-nurbs intersection math | 16:09 |
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| nmz787 | is that accessible from brl-python? | 16:16 |
| kanzure | nope | 16:18 |
| kanzure | their work on nurbs-nurbs intersection was in c++ | 16:18 |
| kanzure | and python-brlcad only has access to anything that can be ctypes'd | 16:18 |
| kanzure | so i would have to write a c wrapper around their c++ stuff | 16:18 |
| kanzure | hmm i saw that diybio email where someone is complaining about microfluidics cad, i don't think most cad software is going to be really appropriate | 16:38 |
| kanzure | a generic parts library would be better | 16:38 |
| kanzure | you don't really have to worry about individual part geometry, since most laminar effects can be constructed from standard components and standard shapes | 16:39 |
| nmz787 | you mean sebastian talking about draftsight? | 16:43 |
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| nmz787 | oh, a new reply | 16:43 |
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| nmz787 | he's previously said "I solely do .NET programming" | 17:11 |
| nmz787 | so I wonder if CAD programming is out of the question for hinm | 17:12 |
| kanzure | i don't think that stl is a good export format for microfluidics | 17:12 |
| nmz787 | yeah I think it would be faster to export slices directly | 17:15 |
| nmz787 | but it would def be useful for CFD | 17:15 |
| nmz787 | or FEA | 17:15 |
| nmz787 | s/faster/more directly useful/ | 17:15 |
| nmz787 | I want to try palabos | 17:16 |
| nmz787 | but I pretty much have no free time now until this class is over | 17:16 |
| nmz787 | :( | 17:16 |
| nmz787 | ugh angst already "This laboratory is a University-recognized writing intensive course (WIC). In addition to completing the labs and obtaining and evaluating results, you will be expected to describe your work in reports that are similar to scientific journal articles." | 17:17 |
| kanzure | ssh transparent proxy stuff https://github.com/apenwarr/sshuttle | 17:19 |
| nmz787 | I have no idea why this intersection section of the example is so ugly and difficult looking | 17:19 |
| nmz787 | with implicitCAD it was just union or difference | 17:20 |
| kanzure | implicitcad was not doing mesh-based intersections | 17:21 |
| kanzure | as far as i know | 17:21 |
| kanzure | i believe i warned you that verbnurbs did not have nurbs surface-surface intersection yet | 17:21 |
| nmz787 | yeah but you didn't answer as to if that only related to performance or somthing else | 17:26 |
| kanzure | it's literally not implemented | 17:26 |
| nmz787 | that doesn't answer the question | 17:26 |
| kanzure | what? | 17:27 |
| kanzure | if you didn't want nurbs then you would just use stl mesh "cad" | 17:27 |
| nmz787 | the question is how nurbs and mesh intersection differ/compare/perform-relatively | 17:27 |
| kanzure | nurbs is curves, stl isn't | 17:28 |
| nmz787 | why not mesh the NURBS then intersect... only reason I can see if potentially massive difference in performance | 17:28 |
| nmz787 | the STL is just discretized from the NURBS though | 17:28 |
| kanzure | often there's more than one intersection you want in an object | 17:28 |
| nmz787 | sure | 17:29 |
| nmz787 | that seems unrelated though, or an aside | 17:29 |
| nmz787 | unless you're again coming back to performance | 17:29 |
| nmz787 | saying that there would need to be many more meshes created before intersection occurs | 17:29 |
| nmz787 | but you aren't saying anything really | 17:29 |
| nmz787 | so I can't understand your concern | 17:30 |
| kanzure | anything can be called performance... "the performance of the intersection algorithm" "the performance of the curve" "the memory performance" | 17:30 |
| kanzure | there's a degradation in output quality the more you use meshes | 17:30 |
| kanzure | meshes are not curves | 17:30 |
| kanzure | (naturally, there can be a mesh of curved surfaces but that's not what it means in this context) | 17:31 |
| kanzure | if you take the intersection of two meshes you have a degradation | 17:31 |
| kanzure | if you take the intersection of two curved surfaces you do not have a degradation depending on your intersection algorithm choice | 17:31 |
| kanzure | if your "nurbs" intersection algorithm is "convert both surfaces to meshes, then intersect using bounding boxes" then you will also have a degradation | 17:32 |
| kanzure | anyway, after you convert to a mesh you are stuck with a mesh, rather than a nurbs object | 17:32 |
| kanzure | a perfect nurbs sphere can happen with <100 kilobytes of memory, and a perfect stl mesh sphere would take theoretically an unlimited amount of memory i guess | 17:33 |
| nmz787 | ok, so performance degrades with mesh, cool | 17:36 |
| nmz787 | you could have just said that in the first place | 17:36 |
| kanzure | "performance" | 17:36 |
| kanzure | i don't think that word means what you think it means | 17:37 |
| nmz787 | and "precision/accuracy" | 17:37 |
| nmz787 | sure, with quotes around it makes perfect sense | 17:37 |
| kanzure | there's a lot of knowledge that saying "precision/accuracy/performance" is totally missing out on | 17:37 |
| nmz787 | so what | 17:37 |
| kanzure | well, you're missing out on a lot of potential conclusions that i don't know why you are ignoring | 17:38 |
| nmz787 | the point is I got the info out of you | 17:38 |
| nmz787 | ;) | 17:38 |
| kanzure | uh? | 17:38 |
| nmz787 | no, I am not interested in unlimited resolution, nanometers at most... so bounded by that constraint, performance in general (or time to render a result and how well that rendering is formed) is better for nurbs intersection vs mesh intersection | 17:39 |
| kanzure | rendering is only useful for visualization really, in which case you might as well not use nurbs at all | 17:39 |
| kanzure | or any cad for that matter. it could just be povray or pretty pics painted on walls. | 17:39 |
| kanzure | cad intersection errors are known to cause actual problems | 17:41 |
| nmz787 | wrong, i can't use nurbs for grbl for driving a lithography machine | 17:42 |
| nmz787 | i need it rendered to gcode | 17:42 |
| nmz787 | or BMP | 17:42 |
| kanzure | wasn't this what fenn was telling you about the other day... | 17:42 |
| nmz787 | ? | 17:43 |
| nmz787 | you seem to have forgotten then | 17:43 |
| nmz787 | because why would you not remember needing gcode? | 17:43 |
| kanzure | why have i forgotten? | 17:43 |
| kanzure | huh? | 17:44 |
| kanzure | you generate gcode based on the final model, not the intermediates | 17:44 |
| nmz787 | sure | 17:45 |
| nmz787 | unless you want to test the intermediates or something | 17:45 |
| nmz787 | why do you mention it? | 17:45 |
| kanzure | you are interested in correct models | 17:45 |
| kanzure | without error propagation from mesh-based intersections | 17:46 |
| nmz787 | you wouldn't call that performance related? I would | 17:46 |
| kanzure | performance is just a really vague term | 17:46 |
| nmz787 | a crappy ferrari replica that literally 'cut corners' and didn't run very well would be considered having crappy performance relative to a real ferrari | 17:46 |
| nmz787 | i.e. they intersected their engine head curves with the valves using meshes rather than nurbs | 17:47 |
| nmz787 | vague is good though in some cases | 17:47 |
| nmz787 | it covers all this | 17:47 |
| nmz787 | it makes for not-long-like-this discussions on IRC for example | 17:47 |
| nmz787 | but I digress, you gave reasonable info after some time, so I am happier with that knowedge | 17:48 |
| nmz787 | knowledge | 17:48 |
| kanzure | if you are primarily interested in (especially browser-based) visualizations for human inspection i strongly encourage you to stick to mesh-based intersection algorithms because there's lots of those. and also you will have quicker results and you will be less frustrated and wont blame it on me. | 17:52 |
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| nmz787 | I like accuracy though | 17:55 |
| kanzure | that's valiant and great, but uh, are you sure you need it here? | 18:00 |
| kanzure | for example, you definitely don't need atomic precision | 18:00 |
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| nmz787 | no, but I would like to be able to set it... 'quick view mode' and 'laser printer quality mode', 'laser lithography mode', 'lithography quality mode', 'fib/sem quality mode' | 18:03 |
| poppingtonic | http://www.sfgate.com/business/article/Controversial-DNA-startup-wants-to-let-customers-5992426.php#photo-7342819 | 18:05 |
| poppingtonic | .title | 18:05 |
| yoleaux | Controversial DNA startup wants to let customers create creatures - SFGate | 18:05 |
| poppingtonic | Cambrian Genomics | 18:05 |
| kanzure | wtf cambrian genomics isn't controversial, they are lying | 18:07 |
| nmz787 | this lady thinks it is http://www.geneticsandsociety.org/article.php?id=2081 | 18:09 |
| nmz787 | "Letter to HFEA: Consider the Risks of “Mitochondrial Manipulation” Discussed by the FDA | 18:10 |
| nmz787 | " | 18:10 |
| poppingtonic | crazy bioethicists will be all over this | 18:10 |
| kanzure | crazy bioethicists are crazy and thus should be removed from modern society | 18:10 |
| kanzure | there should be a bioethics of not exposing me to crazy bioethicists | 18:10 |
| poppingtonic | :D | 18:11 |
| nmz787 | some ppl are crazzzy | 18:11 |
| nmz787 | I watched GMO OMG last night | 18:11 |
| nmz787 | dude said something like 'GMOs fall into two basic categories, insecticide producers, and herbicide resistant' | 18:11 |
| kanzure | clearly he is not from this planet | 18:12 |
| nmz787 | and when they talked about bugs having insecticide resistance as a result of tons of spraying, they sounded all horrified, but didn't mention that it just means we're back to where we were before that tech was used | 18:12 |
| nmz787 | and then he was talking about the original version of this paper http://www.enveurope.com/content/26/1/14 | 18:14 |
| kanzure | .title | 18:15 |
| yoleaux | Environmental Sciences Europe | Full text | Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize | 18:15 |
| poppingtonic | .wik gmo omg | 18:20 |
| yoleaux | "A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. GMOs are the source of genetically modified foods and are also widely used in scientific research and to produce goods other than food." — http://en.wikipedia.org/wiki/Genetically_modified_organism | 18:20 |
| kanzure | hrm, isn't this the memex essay thing? http://www.theatlantic.com/magazine/archive/1945/07/as-we-may-think/303881/?single_page=true | 18:24 |
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| poppingtonic | .title | 18:31 |
| yoleaux | As We May Think - The Atlantic | 18:31 |
| nmz787 | it's on netflix | 18:32 |
| poppingtonic | "He may perish in conflict before he learns to wield that record for his true good." | 18:34 |
| kanzure | ~prophecies of the future~ | 18:35 |
| kanzure | sort of | 18:35 |
| nmz787 | .title https://www.youtube.com/watch?v=6NbmnKGT2NM | 18:35 |
| yoleaux | CH427 Expt1 Pot and Spec Detn of pH - YouTube | 18:35 |
| nmz787 | hmm, youtube has share-only videos | 18:35 |
| nmz787 | i.e. this video doesn't show up here https://www.youtube.com/channel/UCVeQxF_sjPfWSYcQ_JpFz8g/videos | 18:36 |
| poppingtonic | nmz787: have you seen DNA Dreams? | 18:36 |
| nmz787 | oO no | 18:36 |
| poppingtonic | It's about the Beijing Genomics Institute. | 18:36 |
| poppingtonic | on youtube. | 18:37 |
| kanzure | ah yes the space heater facility in china | 18:37 |
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| poppingtonic | haha | 18:37 |
| nmz787 | I stopped being interested in BGI a while ago, after I heard some rumors about their data being of questionable quality, and then later when I started looking into funding from them and ITAR | 18:40 |
| poppingtonic | what kind of data was being talked about? | 18:43 |
| kanzure | probably just their reads | 18:44 |
| nmz787 | yeah can't remember where I heard the doubt | 18:51 |
| nmz787 | maybe online | 18:51 |
| kanzure | cory | 18:51 |
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| fenn | very troubling | 21:35 |
| kanzure | sup | 21:36 |
| fenn | bioethicists :( | 21:36 |
| delinquentme | kanzure, you said that you've only looked over configuring graphite right? | 21:36 |
| delinquentme | not actually implemented? | 21:36 |
| delinquentme | fenn, no such thing. | 21:36 |
| kanzure | i have been implicated in the practice of many dark arts | 21:36 |
| delinquentme | the island, its a hollywood tutorial | 21:36 |
| delinquentme | go make it happen | 21:36 |
| kanzure | i am currently not responsible for any active graphite servers | 21:36 |
| fenn | how do i get off the island | 21:37 |
| delinquentme | currently troubleshooting a system | 21:37 |
| delinquentme | fenn, you're already off it. You want to BUILD it | 21:37 |
| fenn | oh | 21:37 |
| kanzure | you are the island | 21:37 |
| fenn | EVERY MAN | 21:37 |
| * kanzure consults with patri friedman's scalp | 21:38 | |
| fenn | phrenologist | 21:38 |
| kanzure | hush | 21:38 |
| kanzure | yeah if bioethics and anti-GMOers have problems with just these very basic concepts, i wonder how they will respond when they learn what sex is | 21:38 |
| fenn | why is it that every bioethicist is solidly AGAINST whatever new technology | 21:40 |
| fenn | what about the billions of people currently dying, what about them! | 21:40 |
| kanzure | also, why isn't mansanto funding anti-anti-GMO bioethicists? | 21:40 |
| fenn | because they don't need to | 21:41 |
| fenn | the just sell corn, man | 21:41 |
| kanzure | at that scale you hedge bets like crazy | 21:41 |
| kanzure | throwing a few dollars to some people to write up ethics of biowhatever is a non-decision for them | 21:41 |
| fenn | i guarantee monsanto has zero research into human genetic engineering | 21:41 |
| kanzure | oh sure | 21:41 |
| kanzure | definitely | 21:41 |
| fenn | i'd love it if the first genetically engineered human was completely indistinguishable from any other human | 21:44 |
| kanzure | you should just claim you're genetically engineered | 21:46 |
| kanzure | by your parents | 21:46 |
| kanzure | through a natural process called fertilization | 21:47 |
| kanzure | i suppose for you to claim this you would first have to believe you're actually human | 21:47 |
| kanzure | and i've never asked you about that | 21:47 |
| * fenn invokes the no-philosophy rule | 21:49 | |
| fenn | soviet union #1 https://en.wikipedia.org/wiki/List_of_best-selling_video_games#All_platforms | 21:55 |
| kanzure | what a strange day | 21:55 |
| kanzure | #slatestarcodex banned me because "hplusroadmap is boring" (and it's infested with #lesswrong people) | 21:56 |
| fenn | huh | 21:56 |
| kanzure | exactly | 21:56 |
| fenn | so much for rationality | 21:57 |
| kanzure | yeah i've been surprised by how weird #lesswrong is | 21:57 |
| kanzure | it's definitely not a rationality group | 21:57 |
| delinquentme | OMGGG finally carbon is running | 21:57 |
| nmz787 | apparently this exists https://groups.google.com/forum/#!forum/coast-to-coast-journal-club | 21:58 |
| kanzure | hmm i don't get those genspace emails | 21:59 |
| kanzure | very curious | 21:59 |
| kanzure | i've always hated how exclusive out-group/in-group genspace has been | 21:59 |
| kanzure | way to run a community | 21:59 |
| kanzure | "Mary Ward here at Counter Culture Labs has been very interested in restarting the journal club, but she can't seem to join the mailing list." | 22:00 |
| kanzure | what? | 22:00 |
| kanzure | "Did anyone else get disconnected from the journal club this afternoon on Ibuprofen and aging?" | 22:00 |
| kanzure | i bet they are using google hangouts :( | 22:00 |
| fenn | lame | 22:00 |
| kanzure | "Someone mentioned that zoom.us doesn't work with linux - that true? Is there any way to mirror it so people can watch in real time at least?" | 22:01 |
| kanzure | man people are just awful | 22:01 |
| kanzure | why are people so awful? | 22:01 |
| kanzure | i think there's this awfulness force field that permeates the world like aether | 22:01 |
| kanzure | and it just gets strongly concentrated in places | 22:02 |
| delinquentme | kanzure, why is this awful ? | 22:02 |
| nmz787 | because they don't just use google hangouts since they're using incompatible/non-free stuff to begin | 22:03 |
| fenn | for one, why would you need a video stream to talk about a journal article | 22:03 |
| kanzure | yes, a video stream is totally stupid for this | 22:03 |
| kanzure | this is the same reason why openworm is evil | 22:03 |
| kanzure | taking up my entire video feed just for your stupid pow-wow is the dumbest thing ever | 22:03 |
| kanzure | i can be in 500 irc channels simultaneously but only one stupid video feed | 22:03 |
| nmz787 | I like the idea of video because it seems social, and a lot of ppl can't type too well | 22:03 |
| kanzure | it's completely limiting and unprofessional | 22:04 |
| fenn | two, why is streaming video such a mess of incompatible (non-)standards | 22:04 |
| nmz787 | but then audio would cover that | 22:04 |
| nmz787 | even just slide synchronization and audio would be nice | 22:04 |
| kanzure | with audio i can only listen to like 5 people talk simultaneously | 22:04 |
| nmz787 | screen share or something, but I don't think google does screen share | 22:04 |
| kanzure | text communication works perfectly well and has worked on the interwebs for like 40 years now | 22:04 |
| nmz787 | yeah but ppl like more immersive experiences | 22:04 |
| kanzure | no they don't | 22:04 |
| kanzure | they are lying | 22:05 |
| fenn | three, why do you need a website to do video | 22:05 |
| nmz787 | wtf why do ppl have big-screen tvs then? | 22:05 |
| nmz787 | it's a booming market! | 22:05 |
| kanzure | video is not immersive | 22:05 |
| kanzure | you are looking at someone's face, who the fuck cares what they look like? | 22:05 |
| delinquentme | asian chick on OKC. sez " if the last girl was asian don't message me " | 22:05 |
| delinquentme | I say: "my last partner was a body pillow with a print of shinji on it." | 22:05 |
| delinquentme | she didn't understand. | 22:05 |
| delinquentme | did I just out azn the azn ? | 22:05 |
| nmz787 | maybe she doesn't know wtf shinji is | 22:06 |
| nmz787 | because she is not that kind of azn | 22:06 |
| fenn | only if you ate roe with it | 22:06 |
| nmz787 | roe vs wade | 22:06 |
| kanzure | also you can generally only have one person speaking at a time in a video conference | 22:07 |
| fenn | image of delinquentme and shinji romantically splashing in the waves | 22:07 |
| kanzure | a video conference is like everything that is wrong about audio conferencing, BUT WITH VIDEO | 22:07 |
| kanzure | i can't believe people fall for this | 22:07 |
| fenn | kanzure: but there's a website too! yay! | 22:08 |
| delinquentme | hahahah | 22:08 |
| delinquentme | kanzoo you're visionary :D | 22:08 |
| nmz787 | lync can do video + multiple audio at once | 22:08 |
| kanzure | i have trouble conducting 100 simultaneous audio conversations | 22:09 |
| kanzure | and not as much trouble conducting 100 simultaneous text conversations | 22:09 |
| kanzure | bandwidth, yo | 22:09 |
| nmz787 | who the hell wants to interact with that many ppl in general at once? | 22:09 |
| nmz787 | regardless of the comms channel | 22:09 |
| kanzure | orchestration and delegation | 22:09 |
| kanzure | you aren't the only people i talk with | 22:09 |
| kanzure | how do you think i have this 50,000 people stalkmatrix | 22:10 |
| nmz787 | you are the only ppl i talk to | 22:10 |
| nmz787 | pretty much | 22:10 |
| kanzure | what | 22:10 |
| kanzure | that's interesting | 22:10 |
| kanzure | i didn't know this | 22:10 |
| nmz787 | i am in like 15 other rooms | 22:10 |
| nmz787 | but don't chat much unless I have a question | 22:10 |
| fenn | nmz787: arent you in the craft beer capital of the world | 22:10 |
| kanzure | whoops, i meant *why not how, above | 22:10 |
| fenn | i mean, portland seems pretty sociable | 22:11 |
| nmz787 | fenn: yeah, the corner stores have high-quality 6-packs for like $7 | 22:11 |
| delinquentme | I've got alot of crime ??? | 22:11 |
| delinquentme | thats noteworthy | 22:11 |
| * delinquentme feels left outs | 22:12 | |
| kanzure | oakland's finest? | 22:12 |
| kanzure | represent | 22:12 |
| kanzure | and peace out | 22:12 |
| fenn | oakland has industrial wasteland i think | 22:12 |
| * kanzure sleeps | 22:12 | |
| fenn | delinquentme: this asian girl who was way too friendly was like "OMG you ate roe, that's so asian, you're more asian than i am!" | 22:13 |
| nmz787 | found an elementary school for sale around here | 22:13 |
| nmz787 | 10k sq ft for $395k | 22:13 |
| nmz787 | with 1.1 acres | 22:13 |
| nmz787 | 2 gyms, lunch room, 4 classrooms, some offices | 22:14 |
| nmz787 | an acre is enough for a goat or two | 22:14 |
| nmz787 | kanzure: ParahSailin what is the easiest/lowest-hanging-fruit for goat-based antibody production? | 22:14 |
| nmz787 | I have anyways been looking at buying a goat | 22:14 |
| fenn | the CNC machinist convention is (was) held in an elementary school full of machinery | 22:15 |
| nmz787 | (to eat it's baby) | 22:15 |
| ParahSailin | i just sold mine | 22:15 |
| nmz787 | ParahSailin: did you just milk it, or generate Ab? | 22:15 |
| ParahSailin | never did anything useful with them | 22:15 |
| nmz787 | hopefully they ate your grass/lawn at least | 22:16 |
| fenn | why are goats trendy now? goats are terrible little animals | 22:16 |
| ParahSailin | i dunno, i got them like 2 years before they were apparently trendy | 22:16 |
| fenn | get a pony | 22:16 |
| nmz787 | ponies are larger and less efficient digestively | 22:17 |
| nmz787 | and also they won't eat brush | 22:17 |
| fenn | so what | 22:17 |
| fenn | a bale of hay is $5 | 22:17 |
| * nmz787 bale a day keeps the starvation away | 22:17 | |
| fenn | also, barley sprouts | 22:17 |
| ParahSailin | in ca a round bale of hay was like $250 this year | 22:18 |
| nmz787 | WOW | 22:18 |
| nmz787 | I just got to push one of those down a big hill last week | 22:18 |
| fenn | because of the drought? | 22:18 |
| nmz787 | it tumbled sideways instead of unrolling cleanly, it was fun to watch | 22:18 |
| nmz787 | damn it was heavy though | 22:18 |
| ParahSailin | i would have kept the goats if i had a choice | 22:18 |
| nmz787 | moving it was pretty much the limit of my strength, I haven't been active much lately :/ | 22:19 |
| nmz787 | but it was packed in the trailer sideways as well | 22:19 |
| nmz787 | so I had to push it out not roll it | 22:19 |
| fenn | if you had a draft pony you could hitch it up to do the work for you | 22:20 |
| nmz787 | you'd also have to train it | 22:21 |
| ParahSailin | why you want goat antibody production | 22:21 |
| ParahSailin | rabbits are like half the size | 22:21 |
| nmz787 | oO | 22:21 |
| nmz787 | that would work too I guess | 22:21 |
| nmz787 | I am not sure which my 'organic' farmer would be less opposed to participating in | 22:21 |
| nmz787 | :) | 22:21 |
| nmz787 | low-input/non-conventional/traditional | 22:22 |
| nmz787 | but what would be the hello world that would be valuable? | 22:22 |
| nmz787 | I can't remember what I did with hybridomas | 22:22 |
| ParahSailin | participating? | 22:23 |
| nmz787 | it might have just been anti-GFP | 22:23 |
| nmz787 | well he would keep watch on them, raise them, tend to them | 22:23 |
| nmz787 | (or at least that was my idea) | 22:23 |
| ParahSailin | you need someone else to do that part? | 22:23 |
| nmz787 | sure why not? | 22:24 |
| nmz787 | that way I can still be programming and doing the higher-level work | 22:24 |
| nmz787 | protocols etc | 22:24 |
| nmz787 | also I don't have land ;) | 22:25 |
| nmz787 | that is the most important part | 22:25 |
| fenn | dont need much land to keep a rabbit | 22:25 |
| ParahSailin | i didnt do hardly shit to take care of the goats | 22:25 |
| nmz787 | http://news.yahoo.com/biomedical-goats-arent-typical-livestock-might-save-life-210546503.html | 22:26 |
| nmz787 | yeah but I literally cannot have goats where I live now | 22:26 |
| nmz787 | rabbits probably though | 22:26 |
| ParahSailin | the perennial story: goats making spider silk in milk | 22:27 |
| nmz787 | GMO milk goats would be a stretch goal I guess | 22:27 |
| nmz787 | "Goats already produce a number of antibodies in their milk—that’s how a kid first develops its immune system. So scientists just add in one more. | 22:28 |
| ParahSailin | you're gonna have to sacrifice it to extract spleen, so best pick an animal you wouldnt mind killing | 22:28 |
| nmz787 | " | 22:28 |
| nmz787 | I read that they often do peritoneal (I think) implants, then regular tumor/cyst/bulge extractions from there | 22:28 |
| fenn | nmz787: if you're reading any article talking about "scientists" you're so far from knowing what's necessary you might as well not even have started | 22:28 |
| nmz787 | http://www.nature.com/news/discovery-of-goat-facility-adds-to-antibody-provider-s-woes-1.12203 | 22:29 |
| ParahSailin | anti-venom is usually done as a polyclonal extract | 22:29 |
| ParahSailin | so i guess you dont have to kill for that | 22:29 |
| nmz787 | http://www.newyorker.com/tech/elements/valuable-antibodies-at-a-high-cost | 22:29 |
| nmz787 | "Santa Cruz Biotech is owned by John and Brenda Stephenson, who have spent the past fifteen years acquiring forty-four thousand hilly acres along California’s central coast, in hopes of restoring the historic San Juan Ranch to its former peak of nearly sixty thousand acres." | 22:30 |
| nmz787 | wow! | 22:30 |
| nmz787 | shit, that is another league of acreage | 22:30 |
| nmz787 | 841 goats in total | 22:31 |
| nmz787 | well, 1/841*(their income per year) = ? | 22:31 |
| nmz787 | supposed revenue is 10-25 mil | 22:32 |
| nmz787 | "Equine Manager" on their careers page | 22:33 |
| nmz787 | I guess they also have a pony | 22:33 |
| fenn | that was just one barn | 22:33 |
| nmz787 | "Equine Manager" | 22:33 |
| nmz787 | I mean "CRISPR Research Assistant" | 22:33 |
| nmz787 | interesting | 22:33 |
| nmz787 | "Purifies recombinant antibodies from rabbit sera by affinity column according to method provided by supervisor" | 22:34 |
| ParahSailin | thats odd that they would have recombinant antibody from serum | 22:35 |
| ParahSailin | like, they found a monoclonal producing line, rabbitized it, and then transgened a rabbit with it so they could express it in vivo? | 22:38 |
| nmz787 | ah | 22:41 |
| nmz787 | sounds plausible | 22:41 |
| delinquentme | WAO. | 23:20 |
| delinquentme | Wao. | 23:20 |
| delinquentme | wao. | 23:20 |
| delinquentme | much graph. | 23:20 |
| delinquentme | very uptime. | 23:20 |
| nmz787 | hmm, brlcad has some wavelet stuff | 23:35 |
| --- Log closed Mon Jan 05 00:00:13 2015 | ||
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