| --- Log opened Mon Jan 26 00:00:35 2015 | ||
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| archels | "Without the title of PhD, there is no room for you at a university. With the title, there often also isn't." | 04:00 |
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| archels | 4300 received PhD title in The Netherlands in 2013 | 04:03 |
| chris_99 | is there a list somewhere of the number of PhDs awarded per country | 04:04 |
| archels | not sure, this is from a recently released study/review of PhDs in Holland alone | 04:06 |
| kanzure | "degrading things that i have hired postdocs to do for me for very little pay: ...." | 04:17 |
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| kanzure | hello eudoxia | 04:18 |
| eudoxia | good morning kanzure | 04:18 |
| kanzure | i am looking for a gasoline or other liquid microengine design | 04:21 |
| kanzure | or a miniaturized stirling engine | 04:21 |
| eudoxia | what would you use those for? tiny actuators? | 04:23 |
| kanzure | indeed | 04:23 |
| kanzure | i'm aware of other mems actuators but they all have pathetic outputs... like 0.001 newtons. | 04:23 |
| eudoxia | are you building a telescope or some other heavy thing that needs actuators | 04:26 |
| kanzure | almost everything needs actuatrs | 04:27 |
| kanzure | *actuators | 04:27 |
| eudoxia | yeah but if you're looking for something with a lot of N's i imagined you wanted to push something really heavy around | 04:28 |
| kanzure | http://diyhpl.us/~bryan/papers2/mems/Pneumatic%20and%20hydraulic%20microactuators:%20a%20review.pdf | 04:29 |
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| eudoxia | are there piezoelectric elements that fit what you need? | 04:29 |
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| kanzure | not to my knowledge | 04:33 |
| kanzure | "Millimeter-scale, MEMS gas turbine engines" http://files.asme.org/IGTI/Knowledge/Articles/13045.pdf | 04:35 |
| kanzure | hm. | 04:39 |
| kanzure | eudoxia: the reason why is because photolithography of actuation devices would be very useful | 04:40 |
| eudoxia | kanzure: i think that has been done, at least for weak MEMS actuators, not miniature heat engines | 04:42 |
| kanzure | need moar power | 04:44 |
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| kanzure | eudoxia: also because moving big things is useful, even if you have mems | 04:54 |
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| kanzure | why don't i know anyone that bought anabolic steroids from silk road? | 05:19 |
| kanzure | http://www.businessweek.com/articles/2015-01-22/global-internet-greg-wyler-may-beat-elon-musk-google-facebook | 05:34 |
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| kragen | kanzure: have you looked at Perry Metzger's commits to NetBSD? | 07:06 |
| kanzure | no | 07:11 |
| kragen | it might be helpful if you want to perform software stylometry | 07:14 |
| kragen | on his C, at least, although that's not C++ | 07:14 |
| eudoxia | i thought we'd established satoshi used windows | 07:14 |
| eudoxia | pmetzger uses os x | 07:14 |
| kragen | stylometry probably isn't robust to active deception attempts anyway | 07:17 |
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| justanotheruser | kanzure: is there a roadmap anywhere other than the name? | 07:50 |
| justanotheruser | go to wiki, ctrl+f "road", only link is hplusroadmap and it doesn't have a roadmap | 07:51 |
| eudoxia | this is the closest thing http://diyhpl.us/wiki/projects/proposals/ | 07:52 |
| kanzure | yes there used to be an actual roadmap that i never revised | 07:55 |
| kanzure | this would have been around 2007 | 07:55 |
| justanotheruser | :( | 07:57 |
| souljack | Trying to get a MyVu for #5 cheap, it looks easy enough to butcher into a mountable display. | 07:57 |
| kanzure | didn't they stop making those | 07:58 |
| souljack | I think so | 07:58 |
| souljack | they still pop up here and there on ebay etc though | 07:59 |
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| the8thbit|work | kanzure: Yeah, I used that, and they told me to go to the NEURON forums, but the NEURON forums wont authorize my account, and I don't know how to get a hold of their admins :( | 08:15 |
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| kanzure | "I've been teaching programming to non-CS students at Stanford for the past month...they're all clearly smarter than me. But what they lack, as does virtually every non-programmer I've worked with, is the ability to (initially) understand a for-loop. It's not that they don't get that there is such a thing as a "loop", or that a task can be broken up into iterations...they just don't know what it means to design something that can iterate ... | 08:52 |
| kanzure | ... across a collection and, for each member of that collection, perform a task on it. It's not merely not understanding the syntax, or the overall result...it's not comprehending that you can design and control such a thing. I've worked with non-programming professionals in which I've taken a repetitive task, such as extracting a bit of text from each page of thousands of pages of documents, and boiled it down to a program that saves ... | 08:52 |
| kanzure | ... them days of work. The effect of such a program is greatly appreciated...but time and time again, these non-programmers are delighted/astounded when I perform the same task in another scenario...what bothers me is all the times when I'm not there to recognize how such a problem can be abstracted, and they dive in head first into a meaningless, repetitive chore." | 08:52 |
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| archels | Xplore is under maintenance. | 09:15 |
| archels | grm | 09:15 |
| archels | paper of the day: Effect of Mechanical Stress on Apple Impedance Parameters E. Vozáry, P. Mészáros | 09:22 |
| kanzure | hm. | 09:22 |
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| kanzure | http://www.technologyreview.com/view/534481/first-videos-created-of-whole-brain-neural-activity-in-an-unrestrained-animal/ http://arxiv.org/abs/1501.03463 | 09:50 |
| kanzure | "The ability to acquire large-scale recordings of neuronal activity in awake and unrestrained animals poses a major challenge for studying neural coding of animal behavior. We present a new instrument capable of recording intracellular calcium transients from every neuron in the head of a freely behaving C. elegans with cellular resolution while simultaneously recording the animal's position, posture and locomotion. We employ ... | 09:51 |
| kanzure | ... spinning-disk confocal microscopy to capture 3D volumetric fluorescent images of neurons expressing the calcium indicator GCaMP6s at 5 head-volumes per second. Two cameras simultaneously monitor the animal's position and orientation. Custom software tracks the 3D position of the animal's head in real-time and adjusts a motorized stage to keep it within the field of view as the animal roams freely. We observe calcium transients from ... | 09:51 |
| kanzure | ... 78 neurons and correlate this activity with the animal's behavior. Across worms, multiple neurons show significant correlations with modes of behavior corresponding to forward, backward, and turning locomotion. By comparing the 3D positions of these neurons with a known atlas, our results are consistent with previous single-neuron studies and demonstrate the existence of new candidate neurons for behavioral circuits." | 09:51 |
| kanzure | ("Whole-brain calcium imaging with cellular resolution in freely behaving C. elegans") | 09:51 |
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| kanzure | pffft they didn't test their data against openworm | 09:53 |
| kanzure | are we supposed to take this seriously | 09:53 |
| kanzure | "spinning disk microscopy" | 09:54 |
| superkuh | The leiferlab "people" page is pretty funny. | 09:55 |
| superkuh | http://leiferlab.princeton.edu/people.php | 09:55 |
| kanzure | "Outside of work, he likes to play tug of war against fish and read about trivial issues such as arms control." | 09:57 |
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| Zinglon | Hello | 11:46 |
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| Zinglon | Does anyone here know anything about Neuroprosthetics? | 11:52 |
| archels | .g how to ask questions on irc | 11:53 |
| yoleaux | http://www.catb.org/esr/faqs/smart-questions.html | 11:53 |
| nmz787_i | .wik neuroprosthetics | 11:57 |
| yoleaux | "Neuroprosthetics (also called neural prosthetics) is a discipline related to neuroscience and biomedical engineering concerned with developing neural prostheses. They are sometimes contrasted with a brain–computer interface, which connects the brain to a computer rather than a device meant to replace missing biological functionality." — http://en.wikipedia.org/wiki/Neuroprosthetics | 11:57 |
| nmz787_i | Zinglon: yes | 11:57 |
| nmz787_i | I was reading about a 3d-printed ear last week, that had nerves and everythin | 11:58 |
| Zinglon | Nice!, Sorry to bother you with my question it was just i was looking up stuff about Memory prosthetics and wanted to know if it was legit | 12:00 |
| kanzure | depends on what you mean by legit | 12:10 |
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| Zinglon | Some articles just sound too good to be true, restoring lost memories and such | 12:15 |
| Zinglon | http://spectrum.ieee.org/biomedical/bionics/darpa-project-starts-building-human-memory-prosthetics | 12:16 |
| Zinglon | Hmm could be implanted within four years... | 12:16 |
| kanzure | you should look around for memory engram stuff, which iirc nobody has figured out | 12:16 |
| Zinglon | Thank you kanzure! | 12:17 |
| chris_99 | nmz787_i, got your laser machine yet? | 12:17 |
| maaku | btw kanzure did kaj find you? | 12:17 |
| maaku | i want him to submit his project to futureoflife.org for funding | 12:18 |
| maaku | now that they have money | 12:18 |
| maaku | and maybe it will pull him away from MIRI craziness :P | 12:19 |
| kanzure | yeah i talked with kaj for a few minutes | 12:24 |
| kanzure | nothing really came of that conversation, i gave him some links i guess | 12:24 |
| Zinglon | I have to log guys, bb! | 12:26 |
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| maaku | :\ | 12:57 |
| kanzure | maaku: i don't offer much.. in fact it's quite a hard thing to pitch... "hey how about doing some really hard work? doesn't that sound like fun?" | 12:58 |
| kanzure | quite possibly the worst pitch in the history of forever | 13:00 |
| maaku | this is true | 13:00 |
| maaku | also a good filter though | 13:00 |
| kanzure | we get some pretty weird trolls in here from time to time | 13:01 |
| kanzure | thanfully the schizophrenics haven't showed up in a while. | 13:01 |
| kanzure | prolly ever since i started saying "mkultra" (thx jrayhawk) | 13:01 |
| archels | yes, the absence is really quite remarkable | 13:06 |
| archels | ergh what was that recent optogenetics paper on implanting memories or something | 13:07 |
| archels | not so recent http://www.sciencemag.org/content/341/6144/387 | 13:07 |
| archels | .title | 13:07 |
| yoleaux | Creating a False Memory in the Hippocampus | 13:07 |
| kanzure | false memories are something different | 13:08 |
| archels | yeah, they relied on earlier activation patterns | 13:08 |
| kanzure | do you know which things have been investigated and thrown out as possible mehcanisms of memory? | 13:09 |
| kanzure | and which things are still on the table | 13:09 |
| kanzure | "Identification and optogenetic manipulation of memory engrams in the hippocampus" (2014) http://dspace.mit.edu/openaccess-disseminate/1721.1/85174 | 13:10 |
| archels | it's not really my field, I think vector (across the population, but not 'population vector') sparse/dense coding theories are being investigated | 13:11 |
| archels | an enormous amount of hippocampal research deals with place fields | 13:12 |
| nmz787_i | chris_99: no :( someone emailed a few days ago saying they forgot to mail it and were re-mailing... this may mean I end up with 2 laser etchers though | 13:13 |
| chris_99 | heh, that'd be cool if you did | 13:13 |
| archels | dentage gyrus would generate a dense population code, which is fed to a densely interconnected CA3 thought to serve as an autoassociative memory | 13:14 |
| archels | CA1 would then read out and sparsify CA3 | 13:14 |
| archels | as always with the brain, the story is not very clear cut and probably never will be | 13:14 |
| archels | also, oscillations | 13:16 |
| kanzure | "oscillations!!!" | 13:16 |
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| nmz787_i | chris_99: when I was looking at the listing a few days ago, I think it may have shown a red laser, which I thought would be a blue one.. no matter though as I plan to replace it with a blu-ray drive laser sled | 13:28 |
| nmz787_i | seems I have another reason to build an interferometer for distance tracking, so that is on my agenda for things to not-get-excited-about-until-my-class-is-done | 13:29 |
| nmz787_i | I'm such a bad student, I spent most of my day yesterday procrastinating | 13:30 |
| nmz787_i | and didn't really work on useful things either, mainly just not feeling focused and ended up screwing around | 13:30 |
| nmz787_i | :/ | 13:30 |
| chris_99 | heh, are you in uni then? | 13:31 |
| nmz787_i | since 2007! | 13:35 |
| chris_99 | hmm, me too i think iirc | 13:36 |
| chris_99 | whatcha studying | 13:36 |
| nmz787_i | degree is biotechnology, minor in bioinformatics | 13:36 |
| chris_99 | nice | 13:36 |
| nmz787_i | I've only taken maybe 3 or 4 classes in the last 2 years | 13:36 |
| chris_99 | is it a PhD/masters/...? | 13:37 |
| nmz787_i | nah | 13:37 |
| nmz787_i | drawn-out B.S. | 13:37 |
| chris_99 | cool, are you doing any of your own projects for it? | 13:37 |
| nmz787_i | more like I'm doing it to further my projects | 13:38 |
| nmz787_i | the degree doesn't require projects or anything like a thesis though | 13:38 |
| nmz787_i | in '07 I was ready to leave my short stint as a laborer, was interested in algae making biofuel, and got into biotech | 13:39 |
| nmz787_i | been wanting to drop out since the first quarter, still hate classes | 13:39 |
| chris_99 | what kind of biofuel do algae make? | 13:39 |
| nmz787_i | day job these days wants a degree to pay me more, so that's as good of a reason to get a degree as I've ever had | 13:40 |
| nmz787_i | whatever kind you want if they're programmed right! | 13:40 |
| chris_99 | ahh | 13:40 |
| nmz787_i | but I think they've done biodiesel and maybe butanol | 13:40 |
| nmz787_i | not efficiently | 13:40 |
| chris_99 | iirc, you can just use alcohol in petrol cars, with some modifications? | 13:40 |
| chris_99 | which you can make by fermenting pulp, using some special yeasties | 13:41 |
| nmz787_i | ethanol absorbs water in leaky pipes | 13:41 |
| nmz787_i | so no good for mass transport in existing infrastructure | 13:41 |
| chris_99 | not sure exactly what you mean | 13:42 |
| nmz787_i | it is more hygroscopic than butanol or petrol or diesel | 13:43 |
| nmz787_i | bad for combustion | 13:43 |
| nmz787_i | bad for metal parts (they'll rust) | 13:43 |
| chris_99 | hmm, according to http://en.wikipedia.org/wiki/Ethanol_fuel though, most cars can run on a blend of 10% | 13:43 |
| nmz787_i | oil pipes leak all the time so this allows moisture into the pipeline | 13:44 |
| nmz787_i | yeeah, mainly to increase octane and help solubilize water that may be pprsent | 13:44 |
| chris_99 | aha | 13:44 |
| nmz787_i | (a shot of water would stall the engine, but dissolved it just lowers efficiency | 13:45 |
| nmz787_i | or, maybe increases NOx | 13:45 |
| nmz787_i | http://info.tek.com/rs/tektronix/images/spectrum-allocations-posterLR.pdf | 13:55 |
| kragen | it can sometimes actually increase efficiency | 14:09 |
| kragen | that depends on a lot of things | 14:09 |
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| ParahSailin_ | algae biofuel doesnt really work if you're trying to have them secrete something rather than harvesting raw bod right? | 14:22 |
| kanzure | you know... i forget. | 14:26 |
| kanzure | i think i figured out that it doesn't work either way, once | 14:26 |
| kanzure | but uh.. i'm not sure now.. | 14:26 |
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| streety | why would water in fuel increase NOx? Would it not lower the combustion temperature and decrease NOx? | 15:03 |
| nmz787_i | I think algae currently don't secrete, which is the goal for a lot of folks... the other way is to harvest algae then spend energy to crack their shells and get the inner oils... but the lysis is more energy than the return | 15:04 |
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| nmz787_i | streety: I was just barfing ideas | 15:04 |
| streety | fair enough, sometimes turns up a golden nugget | 15:06 |
| kanzure | "Hence my concern. I think being "informed" in free market transactions is an assumption but also an impossibility. It's very hard to inform yourself in a climate where all those who are powerful have an incentive to get you to believe something entirely false (keeping you misinformed and thus asserting their power over your decisions). In a world full of conmen, the due diligence required to make informed decisions on even the most ... | 15:13 |
| kanzure | ... basic of transactions becomes rapidly prohibitive to the point of impracticability. This is before we even consider the monumental number of disagreements humans will have on what the truth actually is. Getting accurate information in such a quagmire would be difficult for even those most experienced with a field." | 15:13 |
| kanzure | and: | 15:13 |
| kanzure | "Then maybe we should have a 'protected persons' card that people who are concerned about conmen can have issued to them, that ensures only government-vetted companies can deal with them. Unlicensed companies would be barred from providing services to anyone with 'protected person' status. People like me could opt out of this 'protected person' program and be free to use unlicensed services. Do you think that would be fair?" | 15:13 |
| ParahSailin_ | relying on algae secreting just selects for the ones that have the metabolic advantage of keeping carbon to themselves | 15:31 |
| kanzure | aren't you supposed to dump entire batches that get selfish? | 15:33 |
| ParahSailin_ | i guess youd have to | 15:35 |
| nmz787_i | yeah you'd need to have the right selection system\ | 15:39 |
| kanzure | nmz787_i: find me a mems gasoline engine that produces >1 newton of force | 15:40 |
| nmz787_i | hrmm | 15:40 |
| kanzure | diesel is also okay | 15:40 |
| nmz787_i | are RC plane engines too large (they are not mems) | 15:40 |
| kanzure | needs to be planar | 15:40 |
| kanzure | or mostly planar | 15:40 |
| kanzure | planar-manufacturable | 15:40 |
| nmz787_i | hrmm, maybe take fungal spore generating cells as bio-inspiration? | 15:41 |
| kanzure | huh? | 15:41 |
| nmz787_i | they have like the highest force for natural projectiles | 15:41 |
| nmz787_i | or that one shrimp thing | 15:41 |
| nmz787_i | that knocks out its prey | 15:41 |
| nmz787_i | .wik mantis shrimp | 15:42 |
| yoleaux | "Mantis shrimp or stomatopods are marine crustaceans, the members of the order Stomatopoda. They commonly reach 30 centimetres (12 in) in length, though in exceptional cases have been recorded at up to 38 cm (15 in). The largest ever caught has a length of 46 cm (18 in) in the ocean near Fort Pierce, Florida of USA." — http://en.wikipedia.org/wiki/Mantis_shrimp | 15:42 |
| kanzure | i think you and i are talking about two different things | 15:42 |
| nmz787_i | "Both types strike by rapidly unfolding and swinging their raptorial claws at the prey, and are capable of inflicting serious damage on victims significantly greater in size than themselves. In smashers, these two weapons are employed with blinding quickness, with an acceleration of 10,400 g (102,000 m/s2 or 335,000 ft/s2) and speeds of 23 m/s from a standing start.[9] Because they strike so rapidly, they | 15:42 |
| nmz787_i | generate cavitation bubbles between the appendage and the striking surface.[9] The collapse of these cavitation bubbles produces measurable forces on their prey in addition to the instantaneous forces of 1,500 newtons that are caused by the impact of the appendage against the striking surface, which means that the prey is hit twice by a single strike; first by the claw and then by the collapsing cavitation bubbles that immediatel | 15:42 |
| nmz787_i | follow." | 15:42 |
| nmz787_i | kanzure: well you need somewhere to grab ideas from | 15:43 |
| nmz787_i | http://jeb.biologists.org/content/208/19/3655 | 15:43 |
| nmz787_i | I guess muscle cell mechanisms would be too complex for planar fab | 15:43 |
| nmz787_i | http://rsif.royalsocietypublishing.org/content/10/85/20130187.full.pdf+html | 15:44 |
| nmz787_i | I think the mechanism for the spore ejection is water based | 15:44 |
| nmz787_i | but that might be totally wrong | 15:44 |
| nmz787_i | newscale tech might have something you like | 15:45 |
| nmz787_i | they have some piezo stuff | 15:45 |
| nmz787_i | .g 'mems steam engine' | 15:45 |
| yoleaux | http://www.ttivanguard.com/montrealreconn/powerMEMS.pdf | 15:45 |
| nmz787_i | http://www.eureka.gme.usherbrooke.ca/memslab/docs/PowerMEMS-Rankine-paper.pdf | 15:45 |
| nmz787_i | http://www.dissertations.wsu.edu/Dissertations/Summer2010/h_bardaweel_071510.pdf | 15:46 |
| jrayhawk | there was that tiny wankel engine from a while back | 15:49 |
| jrayhawk | http://berkeley.edu/news/berkeleyan/2001/04/10_cmbus.html | 15:49 |
| jrayhawk | just scale it smaller, i guess? | 15:50 |
| kanzure | "ramping up the engine to produce 30 watts" | 15:50 |
| kanzure | well, to be honest i don't need mems in this case, i just need things-that-are-using-photolithography-and-mems-related-fabrication-techniques-oh-my-god-stop-using-dashes | 15:51 |
| jrayhawk | "The Berkeley team hopes that some day the mini engine can be used to power electronic devices, like computers or robots. Fernandez-Pello sees it as a first step in designing much smaller engines made using micro-electromechanical (MEMS) technology. The mini engine design is ideal for miniaturizing because of its simplicity, and the components are relatively easy to make using silicon etching technology." | 15:52 |
| jrayhawk | well, i guess just email that guy | 15:52 |
| jrayhawk | maybe ask him if he's ever used NE1 | 15:52 |
| kanzure | so 0.04 hp | 15:52 |
| kanzure | that seems a little unfortunate | 15:53 |
| kanzure | how are you going to move big things? | 15:54 |
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| nsh | .title https://twitter.com/sc_k/status/559745423108481025 | 16:07 |
| yoleaux | Sarah Kavassalis auf Twitter: "The explosive reaction of alkali metals and water has until now it has been misunderstood, says new study http://t.co/QXWbZEDFHY" | 16:07 |
| nsh | i mean | 16:07 |
| nsh | .title http://www.nature.com/news/sodium-s-explosive-secrets-revealed-1.16771 | 16:07 |
| yoleaux | Sodium's explosive secrets revealed : Nature News & Comment | 16:07 |
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| kanzure | "What drives exponential improvements?" http://www.eng.nus.edu.sg/etm/research/publications/47.pdf | 16:17 |
| nmz787_i | .wik floating gate | 16:18 |
| yoleaux | "The floating-gate MOSFET (FGMOS) is a field-effect transistor, whose structure is similar to a conventional MOSFET. The gate of the FGMOS is electrically isolated, creating a floating node in DC, and a number of secondary gates or inputs are deposited above the floating gate (FG) and are electrically isolated from it." — http://en.wikipedia.org/wiki/Floating_gate | 16:18 |
| nmz787_i | apparently a way to make non-volatile memory | 16:18 |
| kragen | not just *a* way | 16:27 |
| kragen | but by far the most important way to make non-volatile random access memory | 16:28 |
| kragen | since Flash, other EEPROMs, and EPROMs are made of FG MOSFETs. | 16:28 |
| kragen | FRAM and MRAM aren't, but they're niche. And disks aren't, but they're non-random-access and produced in smaller quantities than Flash these days, although larger capacities. | 16:29 |
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| kanzure | "Experimental verification of the feasibility of a 100 W class micro-scale gas turbine at an impeller diameter of 10 mm" | 16:34 |
| kanzure | hey that is better | 16:34 |
| kanzure | that's like >50 foot pounds per second (metric system can eat me) | 16:35 |
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| kanzure | hi Genestealer | 16:36 |
| Genestealer | hey | 16:37 |
| Genestealer | kanzure i have a question | 16:38 |
| Genestealer | what do you guys talk about here | 16:38 |
| kanzure | Genestealer: http://diyhpl.us/wiki/declaration | 16:39 |
| kanzure | things like http://diyhpl.us/wiki/genetic-modifications | 16:39 |
| kanzure | and http://diyhpl.us/wiki/dna/projects/#igem-2014 | 16:40 |
| Genestealer | i was part of last years iGEM =p | 16:41 |
| Genestealer | funny you sent me that link | 16:41 |
| Genestealer | Started my own team at my university | 16:41 |
| kanzure | igem seems to be on a perpetual quest to remake geocities | 16:42 |
| Genestealer | LOL | 16:43 |
| Genestealer | our project was copper remediation | 16:43 |
| Genestealer | using Shewanella | 16:43 |
| kanzure | Genestealer: one of the projects floating around in this irc channel is http://diyhpl.us/~bryan/nucleic/fbi-diybio-dna-v1.pdf | 16:43 |
| kanzure | nmz787: this one claims 1 kW in a 2 inch cube https://lirias.kuleuven.be/bitstream/123456789/222860/1/08PP134.pdf?origin=publication_detail | 16:45 |
| Genestealer | i see | 16:45 |
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| kanzure | Genestealer: what brings you here? | 17:08 |
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| Genestealer | seems like a cool channel | 17:33 |
| Genestealer | kanzure are you from the US? | 17:34 |
| kanzure | yes | 17:34 |
| Genestealer | have you heard of diybio labs | 17:42 |
| Genestealer | biohackerspaces | 17:42 |
| kanzure | what about them | 17:47 |
| kanzure | i relentlessly stalk all known groups http://diyhpl.us/wiki/diybio/groups | 17:49 |
| kanzure | so if you ask more specific questions i can give you better ansewrs | 17:49 |
| kanzure | *answers | 17:49 |
| Genestealer | i mean im part of one' | 17:50 |
| Genestealer | i was curious if you attend any? | 17:50 |
| kanzure | i definitely don't | 17:50 |
| Genestealer | whats your background | 17:50 |
| Genestealer | mind measking | 17:50 |
| kanzure | first, i don't see how they are related to diybio-- there's some community overlap, but largely they are not related to do-it-yourself | 17:50 |
| Genestealer | it s very related lol | 17:51 |
| Genestealer | creating a homemade thermocycler | 17:52 |
| Genestealer | pcr | 17:52 |
| Genestealer | dna extraction without using fancy kits | 17:52 |
| kanzure | yes, institutationalized non-institutional biology makes perfect sense -_- | 17:52 |
| Genestealer | just curious to know if you are a biologist? =p | 17:52 |
| Genestealer | all im asking | 17:52 |
| kanzure | well i don't have a license if that's what you mean | 17:53 |
| Genestealer | degree> | 17:55 |
| Genestealer | ? | 17:55 |
| kanzure | none | 17:55 |
| Genestealer | high school? | 17:56 |
| Genestealer | or intermittent college student | 17:56 |
| kanzure | fuck college, fuck high school | 17:56 |
| Genestealer | <3 | 17:56 |
| jrayhawk | haha he doesn't want to admit he graduated high school | 17:56 |
| kanzure | it's true :( | 17:56 |
| jrayhawk | sucker! | 17:56 |
| Genestealer | that's where you learn about this stuff is in college LOL | 17:57 |
| kanzure | "if this guy will believe he has to stay in high school he'll believe anything" | 17:57 |
| jrayhawk | no, you learn all this stuff from scholar.google.com | 17:57 |
| kanzure | and also angry professors yelling at you | 17:57 |
| kanzure | that is an important ingredient | 17:57 |
| Genestealer | they dont yell actually | 17:58 |
| kanzure | including classics like "get the fuck out of my lab" | 17:58 |
| Genestealer | they just dont give a shit | 17:58 |
| kanzure | molecular biology professors totally yell | 17:58 |
| jrayhawk | http://sem-proceedings.com/03s/sem.org-2003-SEM-Ann-Conf-s52p01-Invited-MEMS-Rotary-Engine-Power-System-Project-Overview-Recent.pdf is somewhat more interesting | 17:58 |
| Genestealer | i mean i have a degree in biology | 17:58 |
| Genestealer | not one professor yelled at me | 17:58 |
| Genestealer | the problem is their apath to teaching | 17:58 |
| Genestealer | apathy* | 17:58 |
| jrayhawk | "...there are no commercially available diagnostic engine test stands..." | 17:59 |
| kanzure | 4 watts is nothing dude | 18:00 |
| kanzure | .wa 4 watts in foot pounds per second | 18:00 |
| yoleaux | convert 4 W (watts) to foot pounds-force per second: 2.95 ft lbf/s (foot pounds-force per second); Additional conversion: 0.005364 hp (horsepower); Comparisons as power: ~(0.012 ~1/86) × peak power consumption of a NVidia GEForce GPU (graphics processing unit) (300 to 400 W); ~(0.031 ~1/33) × peak power consumption of a Pentium 4 CPU (central processing unit) (~130 W) | 18:00 |
| jrayhawk | piffle | 18:01 |
| kanzure | hm? | 18:02 |
| jrayhawk | someone actually makes a MEMSable gasoline design and all you do is poopoo its power | 18:02 |
| jrayhawk | this is neat stuff | 18:03 |
| kanzure | to be fair, i have been having a very shit day | 18:03 |
| Genestealer | y | 18:04 |
| kanzure | i was wondering about mems actuators because to my knowledge there's no way to do large-scale production (like through spatial light modulation) to produce large-force-effecting actuators | 18:05 |
| kanzure | by large-scale i mean vlsi-style, instead of one-off assembly | 18:05 |
| kanzure | and mostly this was related to questions about having motor assembly of other components or something | 18:05 |
| kanzure | and a few piconewtons of force isn't going to snap anything into place or lift heavy stuffs | 18:05 |
| kanzure | Genestealer: dunno | 18:06 |
| kanzure | neat little store http://www.dronesplus.com/ | 18:22 |
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| jrayhawk | i blame bad days on inflammation | 18:41 |
| jrayhawk | but i blame basically everything on inflammation | 18:41 |
| nsh | i blame basically everything on phlogiston | 18:43 |
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| kanzure | jrayhawk: i realy have no idea what's going wrong today | 19:08 |
| kanzure | lots of impaired cognition. might be bad adderall, but two pills? i doubt it. | 19:09 |
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| ParahSailin_ | wouldnt fuel cell be easier at mems scale than heat engine? | 19:40 |
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| abetusk | kanzure, or anyone else, do you know of the main drawbacks of VCF? Specifically what about VCFs that graph based approaches are trying to address? | 21:48 |
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| kanzure | variant call format? | 21:50 |
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| abetusk | yes | 21:50 |
| kanzure | never heard of this | 21:55 |
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| ParahSailin_ | what about vcf | 22:32 |
| abetusk | People are trying to come up with new approaches to represent genomes. These so-called graph based approaches, like GFA I guess. I was wondering what the main drawbacks of VCF were. | 22:38 |
| ParahSailin_ | vcf is for snps not genomes | 22:38 |
| abetusk | I think maybe because of 1) reference dependence, 2) difficulty of canonical or normalized representation and 3) inability to handle complex variants | 22:38 |
| abetusk | um... | 22:39 |
| abetusk | VCF is for variants | 22:39 |
| ParahSailin_ | polymorphism variant potato potato | 22:39 |
| abetusk | substitutions, indels etc... | 22:40 |
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| Genestealer | are you guys talking about bioinformatics? | 23:03 |
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