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| --- Day changed Sat Feb 07 2015 | ||
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| andytoshi | fenn: idk what is gudkov's conjecture (my 4-manifold-studying officemate wanted it), but we did eventually find the right paper by chasing citations from paperbot's result | 05:13 |
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| kanzure | hmm | 06:45 |
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| kanzure | .title https://www.youtube.com/watch?v=CHr1XJ-j8FE | 08:33 |
| yoleaux | 3150 ton hydraulic forging press - YouTube | 08:33 |
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| kanzure | https://bettercrypto.org/static/applied-crypto-hardening.pdf | 09:07 |
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| heath | .title http://www.rsc.org/chemistryworld/2015/02/uk-government-synthetic-biology-funding-announcement | 10:30 |
| yoleaux | UK announces £40m fund for synthetic biology | Chemistry World | 10:30 |
| heath | .title http://www.kenilworthweeklynews.co.uk/news/local-news/warwick-university-researchers-win-12-million-to-create-new-centre-1-6562228 | 10:30 |
| yoleaux | Warwick University researchers win £12 million to create new centre - Kenilworth Weekly News | 10:30 |
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| kanzure | bloop | 13:43 |
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| eudoxia | .wik the bloop | 13:46 |
| yoleaux | "Bloop was an ultra-low-frequency and extremely powerful underwater sound detected by the U.S. National Oceanic and Atmospheric Administration (NOAA) in 1997. The sound was consistent with the noises generated by icequakes in large icebergs, or large icebergs scraping the ocean floor." — http://en.wikipedia.org/wiki/The_Bloop | 13:46 |
| kanzure | it was me | 13:46 |
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| kanzure | .to yashgaroth we should add "continuous dna synthesis" to the todo list... continuous operation should be possible if you can safely isolate products while synthesizing others (perhaps through mechanical tip under the surface that moves small magnetic beads out of their chambers and to flush outlets) | 14:15 |
| yoleaux | kanzure: I'll pass your message to yashgaroth. | 14:15 |
| kanzure | oh he is here | 14:15 |
| kanzure | yashgaroth: hi | 14:15 |
| yashgaroth | ah hello | 14:15 |
| yoleaux | 22:15Z <kanzure> yashgaroth: we should add "continuous dna synthesis" to the todo list... continuous operation should be possible if you can safely isolate products while synthesizing others (perhaps through mechanical tip under the surface that moves small magnetic beads out of their chambers and to flush outlets) | 14:15 |
| kanzure | fuck | 14:16 |
| yashgaroth | sure why not | 14:16 |
| kanzure | most machines are batch-operated | 14:17 |
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| kanzure | maybe there's not that much cost savings from continuous operation tho | 14:18 |
| kanzure | if you always had things to synthesize and you were doing spatial light modulation to control sequences on an array/grid then continuous operation means you would always be synthesizing something in every spot | 14:18 |
| yashgaroth | depends on your needs | 14:19 |
| kanzure | "getting a workable idea that doesn't suck" | 14:19 |
| yashgaroth | heh | 14:21 |
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| kanzure | .title https://news.ycombinator.com/item?id=9015570 | 16:53 |
| yoleaux | Transcriptic, a robotic cloud biology lab, is hiring scientists and engineers | Hacker News | 16:53 |
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| maaku | fenn: i hope you are applying? | 17:10 |
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| kanzure | hehe http://www.npr.org/blogs/health/2014/04/23/305890574/dirty-money-a-microbial-jungle-thrives-in-your-wallet | 18:12 |
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| kanzure | i'm surprised by how "off" tyler's marketing is for his transcranial ultrasound company | 19:07 |
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| nameng | paperbot http://www.nature.com/nphys/journal/vaop/ncurrent/full/nphys3233.html | 19:53 |
| paperbot | http://libgen.info/scimag/get.php?doi=10.1038%2Fnphys3233 | 19:53 |
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| nameng | paperbot http://www.nature.com/nphys/journal/vaop/ncurrent/full/nphys3233.html | 19:54 |
| paperbot | http://libgen.info/scimag/get.php?doi=10.1038%2Fnphys3233 | 19:54 |
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| kanzure | .title http://www.nature.com/bioent/2004/040801/full/bioent821.html | 20:07 |
| yoleaux | What every CFO should know about equipment financing : Article : Bioentrepreneur | 20:07 |
| kanzure | "Additionally, a request by the lender for an option to invest in future private equity rounds is a negotiable item. In the current market, typical terms would include single-digit interest rates, a 36–48-month payback period and minor warrant provisions." | 20:09 |
| kanzure | "Because laboratory equipment used by life science companies is diverse and useful for many years, leasing is generally not a practical or cost-effective solution for such companies. Negotiating leases on many individual pieces of equipment is time-consuming and daunting and, furthermore, in the biotech industry there is little justification for having the flexibility to return leased equipment. Therefore, it is almost always in the best ... | 20:10 |
| kanzure | ... interest of a life science company to enter into a loan agreement instead of a lease." | 20:10 |
| nmz787 | how many neurons does c elegans have, how many are i/o to sensory inputs or outputs? | 20:17 |
| kanzure | 100ish i think | 20:19 |
| kanzure | definitely less than 1000 neurons | 20:19 |
| nmz787 | .wa avg length and width of a neuron | 20:20 |
| kanzure | 1031 cells, 302 neurons | 20:20 |
| yoleaux | nmz787: Sorry, no result! | 20:20 |
| nmz787 | wondering what the most interesting microelectrode array would be dimension and pixel-size | 20:20 |
| nmz787 | 1000 i/o is do-able with an FPGA I think | 20:21 |
| kanzure | .g marblestone boyden interfaces filetype:pdf | 20:23 |
| yoleaux | http://web.mit.edu/amarbles/www/docs/ADAM_MARBLESTONE_CV.PDF | 20:23 |
| kanzure | .g marblestone boyden interfaces filetype:pdf thesis | 20:23 |
| yoleaux | http://web.mit.edu/amarbles/www/docs/ADAM_MARBLESTONE_CV.PDF | 20:23 |
| kanzure | those fuckers | 20:23 |
| kanzure | anyway, read his thesis | 20:24 |
| nmz787 | wow, 1200 i/o FPGA on digikey is $20k | 20:24 |
| nmz787 | 976 i/o is $8.6k | 20:24 |
| nmz787 | guess multiple smaller would be needed | 20:25 |
| nmz787 | or like 20 arduinos | 20:25 |
| nmz787 | "Optimistically, simulations of neural activity suggest that 5-10 neurons per electrode may be distinguishable using current spike sorting algorithms517,567,100. A limit of ∼10 neurons per electrode would imply N = 7.5 × 106 electrodes to record from all neurons in the mouse brain, which could be accomplished by positioning recording sites on a cubic lattice with ∼40 µm edge length." | 20:33 |
| nmz787 | "ADAS1256 resolution 16 bits Channel Count 256 price $256" | 20:39 |
| nmz787 | .title http://www.analog.com/en/press-release/11_27_12_ADI_256Channel_16Bit_Digital_XRay/press.html | 20:40 |
| yoleaux | Analog Devices’ 256-Channel, 16-Bit Digital X-Ray Analog Front End Delivers Industry’s Best Combination of Noise, Power and Image Quality | Press Releases | Analog Devices | 20:40 |
| nmz787 | this is more reasonable, at around $80 (1 kilunits) http://www.ti.com/product/afe0256 | 20:40 |
| nmz787 | .title | 20:40 |
| yoleaux | AFE0256 | Current Input ADC | Analog to Digital Converter | Description & parametrics | 20:40 |
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| kanzure | .title https://news.ycombinator.com/item?id=9015663 | 21:10 |
| yoleaux | A Xenon flash will cause the Raspberry Pi 2 to freeze | Hacker News | 21:10 |
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| --- Log closed Sun Feb 08 00:00:48 2015 | ||
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