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archels | nmz787: that's EEG that you're describing | 01:14 |
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kanzure | hmph | 05:41 |
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nsh | -- | 11:21 |
nsh | Woo understands that when selling brain drugs, skepticism comes with the territory. “The typical first reaction is, this is bullshit, you guys are snake-oil salesmen,” he says. “We’re not medical doctors nor biochemistry experts, but we are experts in building teams and building products. Like how Elon Musk attacks rockets and electric cars from ‘first principles,’ we see ourselves as applying Silicon Valley aesthetics and operational know-how | 11:21 |
nsh | to the murky world of nootropics.” | 11:21 |
nsh | -- http://fusion.net/story/58131/i-tried-silicon-valleys-favorite-brain-enhancing-drugs/ | 11:21 |
nsh | .title | 11:21 |
yoleaux | I tried Silicon Valley's favorite 'brain-enhancing' drugs -- Fusion | 11:21 |
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poppingtonic | paperbot: http://www.ncbi.nlm.nih.gov/pubmed/20438233 | 12:47 |
paperbot | http://libgen.info/scimag/get.php?doi=10.1037%2Fa0018963 | 12:47 |
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poppingtonic | http://projects.csail.mit.edu/gsb/old-archive/gsb-archive/gsb2000-02-11.html | 12:50 |
poppingtonic | .title | 12:50 |
yoleaux | Yak Shaving | 12:50 |
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justanotheruser | paperbot: http://onlinelibrary.wiley.com/doi/10.1002/hep.27667/abstract | 12:58 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/2856ccdcf5f5c22422998211a45a7f0f.txt | 12:58 |
fenn | RISE is $1/pill and only contains bacopa, theanine, and caffeine? wtf | 13:16 |
fenn | $0.05/pill http://www.swansonvitamins.com/swanson-premium-full-spectrum-bacopa-monniera-500-mg-90-caps | 13:18 |
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fenn | $0.16/pill (i've seen much cheaper) http://www.swansonvitamins.com/jarrow-formulas-inc-theanine-100-mg-60-caps | 13:19 |
fenn | "Together, these faceless armchair scientists seek a common truth—a clean, unharmful way to make their brains better" | 13:24 |
kanzure | one day i hope men will be judged not by the size and shape of their chair but by the quality of their chair's upholstery | 13:25 |
fenn | i just hope these "silicon valley" types don't fuck it all up for everyone | 13:28 |
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justanotheruser | paperbot: http://dx.doi.org/10.1002/hep.27645 | 13:28 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/db819c4a5ed64038c710bb7db2c3429f.txt | 13:28 |
archels | also calling caffeine a nootropic is ugh | 13:33 |
kanzure | agreed, except it may have unusual benefits to some users | 13:35 |
kanzure | so perhaps for a handful of people caffeine is more potent | 13:36 |
kanzure | or if not more potent then maybe effects them in a way that is unequivocably more nootropic than what we know as caffeine effects | 13:36 |
fenn | caffeine is a nootropic, fuck you | 13:36 |
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kanzure | fenn: so btw i guess you disagree with the "nootropic must give you an ability to design better nootropic" definition thing? | 13:37 |
DrVortex | !paperbot | 13:38 |
fenn | it's a stupid definition, mostly because 1) you don't need nootropics to design nootropics, and 2) there aren't any good examples of this happening | 13:38 |
fenn | also, who cares | 13:38 |
fenn | it's like having a replicator that only makes replicators | 13:38 |
DrVortex | paperbot: http://dx.doi.org/10.1038/nature12205 | 13:40 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/25db9beca4b8e0638a55065abd401859.txt | 13:40 |
archels | too much tolerance buildup and side-effects to meet the definition, imho | 13:40 |
archels | but it all depends on your definition | 13:40 |
kanzure | "you don't need nootropics to design nootropics" then what's the point of a nootropic | 13:41 |
DrVortex | Ah it needs the link to the PDF.... | 13:41 |
archels | I consider things like fish oil supplements, vitamin Bs, CDP-choline, racetams, etc nootropic | 13:41 |
kanzure | archels: does everyone experience tolerance? | 13:41 |
kanzure | DrVortex: paperbot does not always work :) | 13:41 |
kanzure | paperbot: http://nature.com/nature/journal/v497/n7451/pdf/nature12205.pd | 13:41 |
archels | probably, due to its mechanism of action | 13:41 |
fenn | fish oil is a nutrient, not a drug | 13:41 |
archels | which is dominantly extracellular afaik | 13:41 |
DrVortex | Yeah, I was trying it on my own paper to see if it gets the PDF which I know is there | 13:42 |
DrVortex | paperbot: http://www.nature.com/nature/journal/v497/n7451/pdf/nature12205.pdf | 13:42 |
kanzure | paperbot seems to be thinking deep thoughts | 13:42 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/8d6cca98ca9df05a6ac4900be41801c3.txt | 13:42 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/8dd5231b5c2aae2a4a29fe1ff32b78ea.pdf | 13:42 |
fenn | people just take too much caffeine, hence the side effects and tolerance | 13:42 |
kanzure | DrVortex: there you go. at least one of those worked. | 13:43 |
DrVortex | Yep. I get it, it needs the link to the PDF. | 13:43 |
kanzure | not always | 13:43 |
kanzure | https://github.com/kanzure/paperbot | 13:43 |
DrVortex | paperbot: http://onlinelibrary.wiley.com/doi/10.1002/anie.201500229/epdf | 13:44 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/ef57d9853983582077589b6729d57906.txt | 13:44 |
kanzure | DrVortex: is your nick a reference to a comic book character, or are you really great at vortices? | 13:45 |
DrVortex | It's a anglicized obfuscation of my actual name. | 13:45 |
DrVortex | paperbot: http://onlinelibrary.wiley.com/doi/10.1002/anie.201500229/pdf | 13:46 |
paperbot | http://diyhpl.us/~bryan/papers2/paperbot/f37579aace81db44b23b6ffd1e9e67b9.txt | 13:46 |
DrVortex | Hmm, so far it has failed if the link isn't a direct link to a PDF file. I suppose it's not handling redirects well. | 13:47 |
kanzure | certain redirects it can handle, others not.. it's hard to guess because it tries multiple backup methods. | 13:47 |
justanotheruser | kanzure: whats the point of a catalyst if it isn't being used to synthesize another catalyst | 13:50 |
kanzure | reuse | 13:51 |
kanzure | control over expression, reaction rates, etc. | 13:52 |
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justanotheruser | I don't see why a nootropic can't just be considered a catalyst for creating useful things that aren't nootropics | 13:54 |
justanotheruser | (and nootropics) | 13:54 |
FourFire | justanotheruser, it depends on what the person taing nootrpics does | 13:56 |
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delinquentme | kanzure, job scheduling softwarz | 15:44 |
delinquentme | celery ? | 15:44 |
kanzure | yep | 15:45 |
delinquentme | no slurm? | 15:47 |
delinquentme | no python RQ? | 15:47 |
kanzure | celery > rq | 15:48 |
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delinquentme | kazoo why. | 16:03 |
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nmz787_i | http://www.semi.org/eu/sites/semi.org/files/docs/Fraunhofer_130924%20Opportunities%20of%20Wafer%20Level%20Embedded%20Technologies%20for%20MEMS%20Devices.pdf | 16:07 |
nmz787_i | 'Opportunities of Wafer Level Embedded Technologies for MEMS Devices' | 16:07 |
kanzure | delinquentme: celery works | 16:19 |
nmz787_i | http://www.nanoscribe.de/en/products/photonic-professional-gt/ | 16:21 |
nmz787_i | .title | 16:21 |
yoleaux | Photonic Professional GT - Nanoscribe GmbH | 16:21 |
nmz787_i | "The next generation 3D laser lithography system, Photonic Professional GT sets new standards in 3D microprinting and maskless lithography. It combines two writing modes in one device: an ultra-precise piezo mode for arbitrary 3D trajectories (FBMS) and the high-speed galvo mode (MBFS) for fastest structuring in a layer-by-layer fashion." | 16:21 |
nmz787_i | I want /that/ 3D printer for my birthday | 16:23 |
delinquentme | nmz787_i, we need one | 16:23 |
delinquentme | kanzure, we don't have established protocols for stealing massive expensive equipment | 16:24 |
delinquentme | you know dis. | 16:24 |
kanzure | nah where would i store it | 16:28 |
delinquentme | .............................. | 16:30 |
delinquentme | kanzure, i thought you were handling the hplus warehouse | 16:30 |
delinquentme | you're in TX im in CA ... so we need it centrally located | 16:31 |
delinquentme | like .... | 16:31 |
delinquentme | montana | 16:31 |
kanzure | taking the average of positions to place storage is silly | 16:32 |
kanzure | "yes let's pick a spot where neither of us are" | 16:32 |
kanzure | that'll.... work... | 16:33 |
delinquentme | i know. | 16:34 |
delinquentme | you dont have to say it. I know . much clever. | 16:34 |
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nmz787_i | that one would go into it's own special room... i will buy a house appropriately | 16:36 |
kanzure | fenn: when russia's economy collapses again, do you want to go shopping for old soviet equipment? | 16:37 |
fenn | i'll take 3 nuclear subs and a tu-160 please | 16:38 |
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kanzure | gourneau: yo | 17:08 |
fenn | wut | 17:11 |
kanzure | fenn: funny email is funny | 17:11 |
fenn | "seriously? i bothered to email you? why? what's wrong with me?" | 17:12 |
kanzure | "seriously? i put ads on that page?" | 17:13 |
fenn | gourneau: we met at science hack day, the beard detector | 17:16 |
kanzure | he doesn't seem to be online at the moment, actually | 17:16 |
kanzure | i've been trying to get him in here for many years | 17:17 |
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fenn | idle 6 hours | 17:17 |
kanzure | hmm. | 17:17 |
kanzure | irc wandering | 17:17 |
fenn | gourneau: anyway i was wondering what the hell is synthego and why is it not transcriptic | 17:19 |
nmz787_i | fenn: synthego wants to be transcriptic-on-a-chip | 17:20 |
gourneau | yo fenn and kanzure | 17:20 |
gourneau | That isn’t really what synthego is aiming for nmz787_i. We are just doing lab automation stuff :) | 17:21 |
kanzure | synthego wasn't doing on a chip stuff | 17:22 |
kanzure | unless they switched | 17:22 |
kanzure | i think synthego was probably crippled by a certain person if delinquentme's information was accurate | 17:22 |
nmz787_i | that's what they told me when I interviewed with them a while ago | 17:23 |
nmz787_i | I think | 17:23 |
nmz787_i | or maybe that's what I surmised | 17:23 |
gourneau | nope, no chips here right now :/ | 17:23 |
nmz787_i | they said they wanted to do DNA synthesis on-chip as a first product | 17:23 |
fenn | crippled meaning investor said "chips are too finicky, do something else"? | 17:23 |
nmz787_i | but that was like 2 years ago, around the time they had that launch party | 17:23 |
kanzure | fenn: nah a certain person | 17:24 |
kanzure | when i talked with synthego in 2012 they wanted to do robotic liquid pipetting | 17:24 |
kanzure | whoops, 2013 | 17:24 |
fenn | not an uncertain person? | 17:25 |
kanzure | i mean some people have a tendency to steal money and derail operations | 17:25 |
fenn | maybe they were uncertain about stealing the money | 17:25 |
fenn | like, if i buy this yacht for the company, is it really stealing? | 17:25 |
fenn | anyway i'm more interested in the robotics | 17:26 |
kanzure | why? you should be more interested in criticizing opentrons' choices or something | 17:26 |
fenn | i like opentrons' choices though | 17:26 |
gourneau | How is the project going btw? | 17:27 |
fenn | havent checked since they finished the kickstarter | 17:27 |
delinquentme | kanzure, ??? | 17:28 |
kanzure | delinquentme: your same troublemaker used to work there | 17:29 |
fenn | so opentrons is a kickstarter staff pick, but glowing plant is banned for eternity? | 17:29 |
kanzure | or maybe still does | 17:29 |
* fenn scratches his head in confusion | 17:30 | |
kanzure | fenn: opentrons did not cause ETC Group to write a hatemail campaign to journalists | 17:30 |
fenn | "Do your first DNA assembly by hand or with an OT.One, boot it up in a bacteria, see it glow!" | 17:30 |
kanzure | therefore kickstarter doesn't care | 17:30 |
fenn | what's with corporations being so lame | 17:30 |
fenn | .wik ETC group | 17:31 |
yoleaux | "ETC Group is an international organization dedicated to "the conservation and sustainable advancement of cultural and ecological diversity and human rights." The full legal name is Action Group on Erosion, Technology and Concentration. "ETC" is intended to be pronounced "et cetera."" — http://en.wikipedia.org/wiki/ETC_Group | 17:31 |
delinquentme | from what I know synthego is still kicking butt?? | 17:31 |
fenn | what about my right to grow glowing plants | 17:31 |
kanzure | etc group is the same people that were telling the media that diybio was full of bioterrorists | 17:32 |
kanzure | and that transhumanists were going to blow up the planet or something | 17:32 |
fenn | at this rate... | 17:32 |
gourneau | “The ETC Group has released several comic-style illustrations regarding "Synthia", the cell with the first synthetic genome created by Craig Venter”, https://www.youtube.com/watch?v=cXQhJPdlElY lolz | 17:33 |
fenn | transgenic bacteria "don't count" apparently | 17:33 |
gourneau | hah “Synthia” literally has a evil mustache in that video | 17:35 |
kanzure | etc group is a waste of time | 17:35 |
kanzure | don't feed the trolls, etc | 17:35 |
nmz787_i | awww MONKEY | 17:36 |
fenn | i'm suing ETC group for loss of brain cells | 17:36 |
nmz787_i | synthia looks more like an owl | 17:38 |
nmz787_i | http://www.freevector.com/site_media/preview_images/FreeVector-Owl-Cartoon.jpg | 17:38 |
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nmz787_i | /more/ than an owl, it looks like an evil owl | 17:39 |
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fenn | "Chiu and Mitch are in Shenzhen working on manufacturing, and have completed the first five "alpha" robots of our production run. ... the first one from the scaled up production (on the right below) has been back in Brooklyn for a week. Everything is all tested and good-to-go!" | 17:42 |
fenn | (opentrons production update) | 17:42 |
kanzure | ugh hieroglyphics | 17:55 |
fenn | completely unrelated, i've been hanging out with the archive folks and this "internetarchive.bak" thing has started gathering momentum: https://news.ycombinator.com/item?id=9147719 http://archiveteam.org/index.php?title=INTERNETARCHIVE.BAK | 17:57 |
fenn | they are now (an hour ago) talking about proof of storage/proof of retrievability https://cseweb.ucsd.edu/~hovav/dist/verstore.pdf | 17:58 |
fenn | (more hieroglyphics) | 17:58 |
fenn | there's some overlap with bitcoin-wizards | 17:59 |
cluckj | sweet | 18:03 |
kanzure | i have read this paper | 18:03 |
fenn | plz explain it to the rest of us | 18:03 |
fenn | i see all those sigmas and my eyes just stop working | 18:04 |
kanzure | hmm maybe it was not this paper in particular. but i have definitely done some reading on proofs of retrievability. | 18:04 |
kanzure | i don't think that proofs of storage are going to be practical really... there's no way to prove something is stored other than reading it back out. | 18:05 |
kanzure | retrievability is probably a better direction | 18:05 |
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fenn | i was more interested in the "does this actually work?" aspect, but the authors are all jazzed about showing how efficient their scheme is | 18:05 |
kanzure | also it is interesting that integrity is pretty easy | 18:05 |
kanzure | well, it's better we talk about those things in -wizards | 18:06 |
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fenn | closure> the geocities torrent currently has 1 leech and 0 seeds :( | 18:07 |
fenn | d'eaux | 18:07 |
kanzure | so a minimum implementation is something like "hash the file, check the hash" | 18:07 |
nmz787_i | ugh, why do all these biotech whatever-starter campaigns all seem like they spew misinformation or aren't totally honest... https://www.indiegogo.com/projects/color-changing-flowers | 18:07 |
kanzure | or actually, a minimum implementation is "load the file, check the file byte for byte" | 18:08 |
fenn | apparently 1TB torrents don't work for many clients | 18:08 |
kanzure | where minimum implementation means most obvious thing | 18:08 |
kanzure | fenn: argh that's infuriating. that should be more widely known. | 18:08 |
kanzure | anyway, i think that you want to be able to query a remote server with various questions, and then have others be able to verify the answers to the questions, even without having the full file themselves | 18:08 |
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nmz787_i | the video is all 'ANTHOCYANINS.... CIRCADIAN RHYTHMS' then later down the page they change it up to 'IT GOES FROM WHITE TO RED' and further 'BLUE IS A STRETCH GOAL' | 18:09 |
kanzure | and also, if you are doing a distributed file storage scheme where multiple parties have complete copies, you obviously want to do watermarked or uh.. the pretext thing where you hash the plaintext but also the other thing that i forget the name of.... | 18:09 |
kanzure | blah what is the name | 18:09 |
kanzure | salt | 18:09 |
kanzure | i suspect that zooko has implemented something like this for tahoe-lafs | 18:10 |
fenn | https://thepiratebay.se/torrent/5923737/Geocities_-_The_Torrent | 18:13 |
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kanzure | also.... i think that certain protocols in this area are easier to implement if you, as the originator of the file, can come up with some queries and challenge-responses-verifiers ahead of time (e.g. while you still have the file) | 18:13 |
fenn | .wik MAC | 18:15 |
yoleaux | "Mac or MAC may refer to:" — http://en.wikipedia.org/wiki/MAC | 18:15 |
kanzure | .wik HMAC | 18:15 |
yoleaux | "In cryptography, a keyed-hash message authentication code (HMAC) is a specific construction for calculating a message authentication code (MAC) involving a cryptographic hash function in combination with a secret cryptographic key." — http://en.wikipedia.org/wiki/HMAC | 18:15 |
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kanzure | like i said... -wizards | 18:16 |
kanzure | they will have you your answer in less than a dozen seconds | 18:16 |
fenn | i'm not sure what the question is | 18:17 |
kanzure | "is this bullshit" | 18:18 |
fenn | "do we even need to worry about proof of retrievability" | 18:18 |
kanzure | also include internetarchive context | 18:19 |
kanzure | for feelgoods | 18:19 |
fenn | i think it's nearing my bedtime | 18:19 |
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fenn | http://www.reocities.com/neighborhoods/ | 18:37 |
kanzure | "For example, in 1992, currency speculation forced the Central Bank of Sweden to raise interest rates for a few days to 500% per annum, and later to devalue the krona.[83]" | 18:41 |
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justanotheruser | paperbot: http://www.sciencedirect.com/science/article/pii/S157400489901006X | 18:58 |
justanotheruser | paperbot? | 18:58 |
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nmz787 | justanotheruser: search google scholar first: http://core.ac.uk/download/pdf/6881182.pdf | 19:31 |
justanotheruser | thanks | 19:41 |
justanotheruser | does paperbot not search google scholar? | 19:41 |
nmz787 | seems paperbot isn't here now, that's the first problem | 19:43 |
nmz787 | last I checked, paperbot did not search google scholar | 19:43 |
nmz787 | that would be smart though | 19:43 |
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nmz787 | it also might be against google's terms of service | 19:43 |
nmz787 | since they probably want you to use some API | 19:44 |
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Shannon | good evening | 19:50 |
nmz787 | hi Shannon | 19:50 |
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JayDugger | Good evening, everyone. | 21:29 |
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justanotheruser | kanzure: where do I get piezo tubes individually (or two at a time) | 21:51 |
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genehacker | piezoelectric tubes? | 22:06 |
genehacker | what for? | 22:06 |
justanotheruser | http://e-basteln.de/index_m.htm | 22:07 |
justanotheruser | this has been on my todo list for a few years now | 22:07 |
justanotheruser | his sourcing is outdated and the ones I checked with required me to buy a few thousand dollars worth of tubes | 22:08 |
genehacker | so why not just do this: | 22:12 |
genehacker | https://jessdea.wordpress.com/2010/05/18/assignment-7-diy-build-your-own-scanning-tunneling-microscope/ | 22:12 |
genehacker | use a piezo buzzer | 22:12 |
justanotheruser | If that wasn't a rhetorical, | 22:14 |
justanotheruser | that is poorly documented and a piezo buzzer has much less precision | 22:14 |
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genehacker | well supposedly a hobby ceramics kiln can be used to make superconductors if properly calibrated, maybe you could make piezoelectric tubes that way? | 22:28 |
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justanotheruser | Would be cool, but way too much active time buying, building and creating using that | 22:32 |
ParahSailin_ | talked to the wefunder guys | 22:34 |
ParahSailin_ | so yeah, i was correct before, there are no implemented sec rules that allow non-accredited investors in accordance to jobs act yet | 22:34 |
kanzure | fascinating | 22:35 |
nmz787 | there is the latest one on instructables I think... or hackaday.io which is pretty good | 22:36 |
nmz787 | but yeah, why not piezo buzzers? | 22:36 |
nmz787 | or a realtime clock crystal | 22:37 |
genehacker | huh foresight.org is down | 22:44 |
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Shannon | hi nmz787 | 23:28 |
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