| --- Log opened Mon Mar 23 00:00:30 2015 | ||
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| kanzure | you guys are boring | 04:49 |
|---|---|---|
| kanzure | paperbot: http://www.sciencemag.org/content/early/2015/01/14/science.1260088 | 04:55 |
| paperbot | http://libgen.info/scimag/get.php?doi=10.1126%2Fscience.1260088 | 04:55 |
| kanzure | paperbot: http://www.sciencemag.org/content/347/6221/543.full.pdf | 04:56 |
| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/52397a0f42e49afe966698b165eb8ef7.pdf | 04:57 |
| kanzure | hmm this list has grown? http://www.3scan.com/the-team/ | 05:05 |
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| kanzure | .title https://www.youtube.com/watch?v=s_esU7xlPjg | 07:17 |
| yoleaux | Matias Sosa - Conciencia (Original Mix) - YouTube | 07:17 |
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| kanzure | .title https://www.youtube.com/watch?v=k_iIyxGP2QM | 08:17 |
| yoleaux | One Man Groove - Broken (Green Martian) - YouTube | 08:17 |
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| kanzure | "BRAIN Initiative Funding Opportunity: New Concepts and Early-Stage Research for Large-Scale Recording and Modulation in the Nervous System" "NIH is interesting in receiving applications for the following funding announcement: http://grants.nih.gov/grants/guide/rfa-files/RFA-EY-15-001.html Applications are six pages for R21 awards of $300K direct cost over two years. The goal is to fund new and untested ideas to exploit brain signals ... | 08:58 |
| kanzure | ... for modulation and recording neural activity. The expectation is for earliest stage R&D with limited or no preliminary data. Applicants may propose prototypes, simulations, benchtop or in vitro tests. Investigators typically not engaged in neuroscience research are especially encouraged to submit proposals to develop out-of-the-box ideas. The NIH goal is to broadly seed many new ideas through this FOA, and estimates funding 15 ... | 08:58 |
| kanzure | ... awards. Please pass this information on to colleagues who may be interested. For more information please contact brain-initiative-FY15-FOA@mail.nih.gov " | 08:58 |
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| kanzure | "Hey Bryan, We'd been looking at this RFA -- I had submitted a U01 for the last Brain Initiative call -- and will definitely be submitting an updated proposal for this R21. More actuated nanoparticle work. Are you submitting something? We're mostly interested in aptamers with nanoparticles, upconverting nanoparticles, nanorods, etc. for different neuroreceptor/neurotransporter targets. " | 09:16 |
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| archels | are you submitting something? :) | 09:30 |
| kanzure | maybe one of these drawings http://www.thebestpageintheuniverse.net/c.cgi?u=irule | 09:35 |
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| poppingtonic | kanzure: do you know anything about proof-of-strength algorithms? | 10:07 |
| poppingtonic | is there literature on the subject you can share? | 10:07 |
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| kanzure | .to poppingtonic i know nothing about proof-of-strength, but try asking in #bitcoin-wizards they like proof-of-* i guess. | 10:29 |
| yoleaux | kanzure: I'll pass your message to poppingtonic. | 10:29 |
| kanzure | .wik conditional gene knockout | 10:40 |
| yoleaux | "Conditional gene knockout aka "conditional sequence deletion" or short: "conditional deletion", is a relatively new technique of genetic engineering, an offshoot of gene knockout technology where a specific target gene is eliminated from a single organ in the body of an experimental animal, rather than the whole body, as conventional gene …" — http://en.wikipedia.org/wiki/Conditional_gene_knockout | 10:40 |
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| kanzure | .title https://news.ycombinator.com/item?id=9251439 | 11:05 |
| yoleaux | 'Mountaineer' Is a Must-Read of Soviet Sci-Fi | Hacker News | 11:05 |
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| kanzure | "t's not FOSS, but the new WebGL-based Onshape[1] from the original Solidworks team looks like it is going to be making waves. It's free for small public projects (Github-style). They are licensing the existing Parasolid and D-Cubed libraries to do constraint-solving[2], which hints at the a) separation of concerns from the CAD UI and back-end layers, and b) complexity of the CAD kernel problem." https://www.onshape.com/ ... | 12:15 |
| kanzure | ... http://plmsource.industrysoftware.automation.siemens.com/plmcomponents/2014/02/11/belmont-technology-licenses-parasolid-2d-dcm-and-3d-dcm/ | 12:15 |
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| chris_99 | nmz787, got my ToF chip :) gonna try and connect it to an RPi to get it running | 12:55 |
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| kanzure | http://biohackacademy.github.io/ | 13:19 |
| kanzure | "non-institutional biology just got institutional again" this is so weird | 13:19 |
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| delinquentme | i think i haz memory issues on lappy | 13:35 |
| fenn | i wonder if mike pesavento (of 3scan) is related to umberto pesavento (who created the first replicator/von neuman universal constructor in conway's game of life) | 13:49 |
| kanzure | pfft yeah because that's a totally normal thing to be wondering | 13:50 |
| kanzure | where'd you dig that up from | 13:50 |
| delinquentme | kanzure, your dev machine? | 13:53 |
| delinquentme | pure mac? | 13:53 |
| delinquentme | hackintosh? | 13:53 |
| kanzure | lenovo thinkpad w520 | 13:54 |
| kanzure | 32gb ram... waiting to upgrade to 64. | 13:54 |
| delinquentme | does yours have the down key which always pops up? | 13:54 |
| kanzure | no | 13:54 |
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| fenn | i dug it out of one of the dark abscesses of my brain | 14:12 |
| nmz787_i | kanzure: maybe you should reformulate your idea of DIYbio or something... since institutions are definitely a thing (any hackerspace is an institution)... maybe you want it to be called non-big-institutional biology> | 14:13 |
| nmz787_i | ? | 14:13 |
| fenn | mmm 32GB of ram... | 14:13 |
| kanzure | what's the point of a diybio about making other people do shit for you | 14:14 |
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| fenn | the NURBS .swf demo was kinda cool | 14:23 |
| fenn | didn't really explain the basis functions though | 14:23 |
| kanzure | was there a "start animation" button that i missed | 14:24 |
| fenn | no? it's not an animation, it's an interactive click and drag the points thing | 14:24 |
| fenn | also there are buttons to change parameter presets | 14:24 |
| fenn | http://geometrie.foretnik.net/files/NURBS-en.swf | 14:25 |
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| kanzure | i thought it was going to show one of those sweep animations | 14:28 |
| fenn | http://fennetic.net/irc/Arkady_and_Boris_Strugatsky_-_Stalker.pdf | 14:32 |
| fenn | (I haven't read it) | 14:32 |
| fenn | oh crap that's in spanish, sorry | 14:33 |
| kanzure | what's wrong with spanish | 14:33 |
| fenn | uh, do you know spanish? | 14:34 |
| kanzure | dude, vivo en tejas | 14:34 |
| fenn | also it was a short story, i thought it was a novel | 14:34 |
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| nmz787_i | may DIY is a spanish acronym... | 14:45 |
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| nmz787_i | s/may/maybe/ | 14:46 |
| nmz787_i | huh, google translate says for 'vivo en tejas' 'live tiles'... but if you make it 'yo vivo en tejas', then it says 'i live in texas' | 14:47 |
| kanzure | how can you not know what vivo mean | 14:49 |
| kanzure | *means | 14:49 |
| kanzure | "Standard Cyborg: Manufactures waterproof, carbon-fiber coated prosthetic legs, using 3D-printing techniques" | 14:51 |
| kanzure | "Since water causes many traditional prosthetics to rust and even break down, amputees typically have to remove them before paddling on a beach or even taking a shower" | 14:51 |
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| kanzure | "Industrial Microbes: Designing microbes that turn natural gas into chemicals. The idea is that biofuels companies typically use sugar to create their chemicals but the high price of sugar is inhibiting their growth. Branding natural gas as "the new sugar", the founders of Industrial Microbes believe they have founder a cheaper way of generating biofuels." | 14:51 |
| kanzure | "MetricWire: Data collection and analysis platform for clinical trials. MetricWire argues that clinical trials are expensive, complicated and often fall behind schedule. The team believes that its mobile platform for collecting and analyzing data, which is open to clinicians and patients, will make it easier to spot underperformance and faster (and therefore cheaper) to make changes." | 14:52 |
| kanzure | "RescheduleMed: Automating scheduling for the medical world. The complexity of hospitals means that scheduling is still largely done on a manual basis and it's a big administrative burden. RescheduleMed hopes to reduce the problem and therefore lower costs by automating the system. The team says it is focusing on graduate medical education as that tends to be where the most complicated scheduling issues are but plans to expand its ... | 14:53 |
| kanzure | ... technology to every hospital department in future. " | 14:53 |
| nmz787_i | more like I didn't know what tejas meant | 14:56 |
| nmz787_i | apparently it is overloaded with: tiles and also with texas | 14:56 |
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| archels | .title http://www.ncbi.nlm.nih.gov/pubmed/25788334 | 15:00 |
| yoleaux | A Synthetic Erectile Optogenetic Stimulator Enabling Blue-Light-Ind... - PubMed - NCBI | 15:00 |
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| nmz787_i | hahah that's like reverse of that CGI movie with blue people | 15:10 |
| nmz787_i | brings a new meaning to the department-store term 'bluelight special' :D | 15:13 |
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| kanzure | "Pembient fights animal poaching through the bioengineering of wildlife products" "by making artificial alternatives to these highly sought-after commodities" (rhino horn) | 16:12 |
| kanzure | their hacker news profile https://news.ycombinator.com/user?id=george88b | 16:12 |
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| kanzure | astronomy stuff http://phys.org/news/2015-03-jupiter-accounts-unusual-solar.html#nRlv | 16:26 |
| kanzure | paperbot: http://www.pnas.org/content/early/2015/03/18/1423252112 | 16:26 |
| kanzure | .title | 16:26 |
| yoleaux | Jupiter’s decisive role in the inner Solar System’s early evolution | 16:26 |
| paperbot | http://libgen.info/scimag/get.php?doi=10.1073%2Fpnas.1423252112 | 16:26 |
| ParahSailin | sounds like the farmer who grew pigs in clean environments and clean food and tried to the rebbe to sign off on the pork | 16:38 |
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| dingo | what was this DCC SEND of file startkeylogger bullshit | 16:54 |
| kanzure | software that yells at you when you lift wrong https://www.youtube.com/watch?v=L_qaqoGXHDU | 16:54 |
| dingo | https://gist.github.com/jquast/40cb360705ec7a4685a9 | 16:56 |
| kanzure | just someone spamming everyone on freenode | 16:56 |
| kanzure | they don't really join any channels | 16:56 |
| dingo | i see | 16:57 |
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| kanzure | http://lifescivc.com/2015/02/where-does-all-that-biotech-venture-capital-go/ | 17:10 |
| kanzure | http://lifescivc.com/2015/01/venture-backed-biotech-today-reflections-on-exits-funding-and-startup-formation/ | 17:10 |
| kanzure | http://lifescivc.com/2014/09/talent-the-biggest-issue-in-biotech-boardrooms-today/ | 17:10 |
| kanzure | http://lifescivc.com/2014/09/early-stage-biotech-venture-scarcity-fitness-fear-and-greed/ | 17:10 |
| kanzure | http://lifescivc.com/2014/09/startups-exits-and-ecosystem-flux-bullish-for-biotech/ | 17:10 |
| kanzure | "Why is biotech startup supply so constrained? First, there aren’t dozens of breakthrough biomedical ideas created every day; while substrate for startups is very rich, figuring out which are likely translate successfully into high impact medicines diminishes the viable number of big, attractive ideas quickly. Second, there are very few biotech venture investors still active today, and fewer still that are focused on early stage ... | 17:10 |
| kanzure | ... company creation. Third, and of critical importance, it’s not easy to start biotech companies, and in most cases requires entrepreneurs with decades of apprenticeship inside larger R&D organizations – navigating the drug discovery and early development process requires experience well beyond simply advanced degrees (MD/PhD)" | 17:11 |
| kanzure | lousy reason | 17:11 |
| kanzure | the real reason seems to be: biologists don't have any money to start their own ventures | 17:11 |
| kanzure | "The later stage financings that have been driving up the aggregate numbers are almost without exception driven by crossover investors (like hedge and mutual funds who typically invest in public companies) or non-traditional partners like big financial institutions. For example, the Alaska Permanent Fund put nearly $300M into Juno Therapeutics during their private rounds, and the eye-popping $450M raised by Moderna was filled out with a ... | 17:18 |
| kanzure | ... broad range of buyside, public-market investors." | 17:18 |
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| kanzure | "On the early stage side, nearly one third of all Series A funding comes from corporate venture capital (CVC) – and this has been increasing over time, as discussed before ( http://lifescivc.com/2012/01/corporate-pharma-vcs-preferred-partners-big-funds/ )" | 17:18 |
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| kanzure | http://lifescivc.com/2014/09/early-stage-biotech-venture-scarcity-fitness-fear-and-greed/ | 17:19 |
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| -!- mode/##hplusroadmap [+o kanzure] by ChanServ | 17:38 | |
| -!- kanzure changed the topic of ##hplusroadmap to: biohacking, nootropics, transhumanism, open hardware | sponsored by george church and the NRA, banned by the Federal Death Administration (4 times) | this channel is LOGGED: http://gnusha.org/logs | http://diyhpl.us/wiki | "ray kurzweil is a pessimist" - george church | 17:39 | |
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| * delinquentme heavy breathing | 18:41 | |
| delinquentme | I've just changed into my first chroot-ed directory | 18:41 |
| delinquentme | this is SO BAD ASS. | 18:41 |
| @kanzure | tomorrow i will how you ram filesystems | 18:42 |
| @kanzure | *show | 18:42 |
| -!- mode/##hplusroadmap [-o kanzure] by kanzure | 18:42 | |
| kanzure | hah "SmartHires: Helps founders make hires from recommendations made by other founders in the same investor’s portfolio." | 18:49 |
| kanzure | "Shift Messenger: Shift Messenger is a service designed to help hourly workers know their shifts, trade shifts and stay in touch with their coworkers." haha.. well at least they will get progress just on the name i guess. (ignore the other 100 attempts that failed) | 18:52 |
| kanzure | and they took gitlab. that's funny too. | 18:52 |
| kanzure | "Cinder: A smart grill. You tell it how you like your steak, it cooks it precisely and texts you when it’s done. Sold $150k in pre-sales in three weeks." | 18:52 |
| cluckj | chroot is neat | 18:52 |
| kanzure | "Bagaveev Corporation: Building rockets specifically to launch nanosatellites. 1/100th the size of a standard ground-to-orbit rocket. Promises to launch 50 rockets per year." http://techcrunch.com/2014/03/26/three-classes-in-boost-vc-is-raising-a-new-fund-with-plans-to-incubate-100-bitcoin-startups-by-2016/ | 18:53 |
| kanzure | "Pakible: Helps companies design and order their physical packaging online. Claims that it will ship 1 million units this month." | 18:53 |
| kanzure | "Vanhawks: An “operating system” for bikes. Handles things like health metrics and theft alerts. It built a bike as a proof of concept, sold $1.3 million worth. Will focus on licensing with bike manufacturers moving forward." | 18:54 |
| kanzure | what? why? "Trackin: Food delivery software. Provides an online ordering system, an analytics dashboard for managers, and a mobile app for employees." | 18:54 |
| kanzure | "Perceptive Labs, which also has funding from Version One Ventures, SHIFT begins today through pre-order campaign, $ 600 accessory (which will retail post-campaign for $ 800), which works with DJI Phantom and 3D Robotics Iris provides a vision sensor, processor and autopilot program to capture stunning aerial shots using object tracking." | 18:56 |
| kanzure | well that's all quite strange. why would anyone want DRM on their grill? | 18:56 |
| kanzure | "I'm not sure; I didn't write that component and I don't think it's been rewritten in probably a decade, just linked against newer versions of SolidWorks. It's ugly but it works, so we only start looking at the internals of SolidWorks when they introduce a new bug that affects us, which hasn't happened in several years. I'm not optimistic, though. Even in normal interactive use, SolidWorks cannot manage to read updated values from a ... | 19:07 |
| kanzure | ... linked Excel spreadsheet upon opening a part (or writing while saving the part) without the embedded Excel window flashing up briefly. Getting SolidWorks and it's Excel child process to both stay in the background isn't really worth much effort to us at the moment, and I do occasionally get the benefit of spotting something breaking when the model flashes up on screen, instead of discovering it much later. It's really something that ... | 19:07 |
| kanzure | ... shouldn't even require COM/OLE style stuff, just some basic command line functionality. But why would a Windows-only app support that method of interaction?" | 19:07 |
| cluckj | you can only use omaha steaks on that grill, of course | 19:07 |
| kanzure | alright, so what you do is put a dna sequencer in the grill | 19:08 |
| cluckj | fuck yeah | 19:08 |
| kanzure | so that only certain steak can be grilled on your drm grill | 19:08 |
| nmz787_i | if by DRM you mean Delicious Ready Meal | 19:47 |
| cluckj | ^ boom | 19:51 |
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| nmz787_i | just a week or two ago some guy was talking about how he made a beer-making machine and hooked it up to send him a text message when it was done or ready to bottle... then took the system and duplicated it for a meat smoker | 20:15 |
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| nmz787_i | unlike that smart grill though, his meat smoker only texted when it was done, but didn't shut itself off (not sure why it didn't, as he was mentioning that once he got a text and had to rush home to shut off the smoker) | 20:16 |
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| kanzure | heath: have you found maaku yet? or fenn, delinquentme, or gourneau. | 23:18 |
| delinquentme | nah | 23:18 |
| delinquentme | i think hes bitcoining | 23:18 |
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| nmz787 | http://metalachi.com/ | 23:40 |
| nmz787 | .title | 23:40 |
| yoleaux | | The Official Casa of Metalachi: The World's First and Only Heavy Metal Mariachi Band | 23:40 |
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| nmz787 | http://spectrum.ieee.org/tech-talk/biomedical/bionics/a-braincomputing-interface-that-lasts-for-weeks | 23:47 |
| nmz787 | http://diyhpl.us/~nmz787/pdf/Soft_curved_electrode_systems_capable_of_integration_on_the_auricle_as_a_persistent_braincomputer_interface.pdf | 23:48 |
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| nmz787 | "he device helped record brain signals well enough for the volunteers to operate a text-speller by thought, albeit at a slow rate of 2.3 to 2.5 letters per minute." | 23:52 |
| nmz787 | s/he/The/ | 23:52 |
| --- Log closed Tue Mar 24 00:00:31 2015 | ||
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