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| fenn | interesting that just acetonitrile and nitrogen is over half the total marginal cost, certainly a place for improvments to be made | 04:15 |
|---|---|---|
| fenn | could cut down significantly on both by using a small air compressor inside the enclosure to do the blow dry and solvent spray steps, and a large flexible bag to deal with changes in volume | 04:16 |
| fenn | would also make the entire machine less of a pain to deal with; nobody wants to haul gas cylinders and toxic waste around | 04:17 |
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| kanzure | http://danielkeating.blogspot.com.au/2012/01/could-we-breed-dogs-as-smart-as-people.html | 05:49 |
| kanzure | "The idea of breeding cephalopods for increased intelligence is touched on in the (great) novel, "Manifold: Time"." | 05:49 |
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| kanzure | ( from https://news.ycombinator.com/item?id=9901154 ) | 05:52 |
| kanzure | CLTV and CSV soft-forks still necessary, but here's an improved implementation proposal for the lightning network, http://lists.linuxfoundation.org/pipermail/lightning-dev/2015-July/000042.html http://ozlabs.org/~rusty/ln-deploy-draft-01.pdf | 05:57 |
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| kanzure | .wik Manifold: Time | 06:04 |
| yoleaux | "Manifold: Time is a 1999 science fiction novel by Stephen Baxter. It is the first of Baxter's Manifold Trilogy (the others being Manifold: Space and Manifold: Origin), although the books can be read in any order because the series takes place in a multiverse." — https://en.wikipedia.org/wiki/Manifold:_Time | 06:04 |
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| kanzure | "An open source xilinx spartan 6 miniPCIe development board" https://github.com/polysome/aggregate-1 | 07:06 |
| kanzure | http://www.anandtech.com/show/8367/intels-14nm-technology-in-detail | 07:11 |
| kanzure | lots of drama in the comments here http://hackaday.com/2015/06/16/ask-hackaday-and-adafruit-the-new-ceo-of-makerbot/#comments | 07:13 |
| kanzure | nasa workmanship standards http://workmanship.nasa.gov/lib/insp/2%20books/frameset.html | 07:18 |
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| kanzure | upverter claims to have 32k open-source hardware designs on their site as of 5 months ago http://blog.upverter.com/post/109594392482 | 07:27 |
| kanzure | parts naming scheme https://blog.octopart.com/archives/2015/07/introducing-cpl-part-numbers | 07:29 |
| kanzure | parody or satire of fecal matter startups https://www.youtube.com/watch?v=DJklHwoYgBQ | 07:33 |
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| fenn | huh i actually wanted to build something like that (more focused on urinalysis) | 08:22 |
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| juri_ | kanzure: beautiful, beautiful drama. | 08:41 |
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| kanzure | i think that the "activator" was not listed in posam docs? | 08:49 |
| kanzure | for the coupling step | 08:50 |
| kanzure | like 2-benzylthiotetrazole | 08:50 |
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| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=d9797743 Bryan Bishop: ABI 391 links >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 08:57 |
| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=0f12d332 Bryan Bishop: include posam consumable materials per slide >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 08:57 |
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| CaptHindsight | so are the POSaM sequencing steps still a mystery? | 09:12 |
| CaptHindsight | are steps missing from the docs? | 09:13 |
| kanzure | haven't checked, will be checking soon (a few hours maybe) | 09:14 |
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| nmz787_i1 | http://hackaday.com/2015/07/17/hacklet-56-brain-hacks/ | 11:11 |
| nmz787_i1 | local talent ;) | 11:11 |
| nmz787_i1 | "[Paul] isn’t just hacking his own mind, he’s creating a library and reference design using the Teensy 3.1. This library will allow anyone to read electroencephalogram (EEG) signals without having to worry about line noise filtering, signal processing, and all the other details that make recording EEG signals hard." | 11:12 |
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| kanzure | grr https://github.com/bitcoin/bitcoin/issues/6454 | 13:06 |
| kanzure | http://space.stackexchange.com/questions/9851/requirements-to-orbit-pluto | 13:08 |
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| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=fe268ed4 Bryan Bishop: link to posam manuals >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 14:52 |
| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e7750f0b Bryan Bishop: attempt fix markdown formatting (lists) >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 14:53 |
| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=97cc38ee Bryan Bishop: Revert "attempt fix markdown formatting (lists)" >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 14:54 |
| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=3ab9d490 Bryan Bishop: second attempt at fixing markdown formatting >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 14:54 |
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| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e9bda999 Bryan Bishop: fix markdown formatting for azole activator catalysts >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 14:55 |
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| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=4c8a6432 Bryan Bishop: include abi391 reagents >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 15:11 |
| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=9b9771bd Bryan Bishop: fix numbered list of bottled reagents >> http://diyhpl.us/diyhpluswiki/dna/synthesis/notes/ | 15:14 |
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| kanzure | .wik curta | 17:11 |
| yoleaux | "The Curta is a small, hand-cranked digital mechanical calculator introduced by Curt Herzstark in 1948. It can be used to perform addition, subtraction, multiplication, division, and (with more difficulty) square roots and other operations." — https://en.wikipedia.org/wiki/Curta | 17:11 |
| kanzure | .title https://news.ycombinator.com/item?id=9903562 | 17:12 |
| yoleaux | EnChroma: Color for the Color Blind | Hacker News | 17:12 |
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| kanzure | there are a lot of slide prep steps | 17:42 |
| kanzure | i wonder if wafers would work | 17:45 |
| kanzure | and i wonder why they didn't try wafers | 17:45 |
| kanzure | perhaps beads would not require as much cleaning | 17:53 |
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| kanzure | "smart beds" | 18:40 |
| kanzure | there is a fish tank filter requirement | 18:45 |
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| CaptHindsight | it's the epoxy silane that gives the flat surface the surface tension in the right range | 19:18 |
| CaptHindsight | the other steps are just cleaning | 19:18 |
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| kanzure | 19:25 <+xentrac> well, what I mean is a kettle that heats water using heat from a molten-salt tank | 20:07 |
| kanzure | 19:26 <+xentrac> so that you can store heat for boiling water on demand until you have a demand | 20:07 |
| kanzure | .wik molten salt | 20:07 |
| yoleaux | "Molten salt is salt which is solid at standard temperature and pressure (STP) but enters the liquid phase due to elevated temperature. A salt that is normally liquid even at STP is usually called a room temperature ionic liquid, although technically molten salts are a class of ionic liquids." — https://en.wikipedia.org/wiki/Molten_salt | 20:07 |
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| kanzure | instead of one-pot ligase reaction stuff, you could sequence dna and then once you find something you like that you have synthesized, you would place it on each spot on a fresh surface. then you would extend the oligos with new base pair additions. (i'm not sure if the chemistry could tolerate this). this would involve inkjetting some pcr'd oligos. | 20:20 |
| kanzure | this approach would sadly take like 1000 rounds. which would also take forever. | 20:21 |
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| --- Log closed Sat Jul 18 00:00:14 2015 | ||
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