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fenn | machine workout video, with customer service! featuring oversize machines and spindle swapping. (brought to you by the color chrome yellow) http://youtu.be/J0CfHFzW2Qk | 05:41 |
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kanzure | let's do that stuff | 07:40 |
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kanzure | "automatic tool change... BUT AROUND CURVED WALLS." | 07:49 |
kanzure | seems to be for whole-floor tool change routing for all spindles | 07:53 |
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Betawolf | http://www.nature.com/articles/srep12488 | 07:59 |
kanzure | .title | 08:00 |
yoleaux | A Magnetic Wormhole : Scientific Reports | 08:00 |
kanzure | http://www.techinsider.io/billionaires-who-want-to-live-forever-2015-9 | 08:00 |
pasky | h, it's a czech company! | 08:00 |
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kanzure | .title https://www.youtube.com/watch?v=vDwzmJpI4io | 08:11 |
yoleaux | A Conversation with Elon Musk - YouTube | 08:11 |
pasky | thank god for google auto-transcripts | 08:12 |
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kanzure | sorta preachy but ignore the preachy parts http://blog.p2pfoundation.net/the-new-monastic-individuals-as-the-change-agents-for-this-transition-period/2012/07/04 | 10:09 |
kanzure | "A comprehensive comparison of the Sun to other stars: searching for self-selection effects" http://arxiv.org/abs/0805.2962 | 10:13 |
kanzure | "A Larger Estimate of the Entropy of the Universe" http://arxiv.org/abs/0909.3983v1 | 10:13 |
kanzure | "Life, gravity and the second law of thermodynamics" http://www.mso.anu.edu.au/~charley/papers/LineweaverEgan2008v2.pdf | 10:14 |
kanzure | other fun things http://www.mso.anu.edu.au/~charley/publications.html | 10:16 |
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nsh | what are self-selection effects? | 11:09 |
nsh | is this some attempt to rehabilitate the anthropic principle to be scientific? | 11:09 |
* nsh expresses preemptive dubiety | 11:09 | |
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nsh | oh, this is pretty sensible from the abstract | 11:10 |
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delinquentme | why does it seem like a billion things can go wrong in the process of getting things secreted from cells? | 11:18 |
kanzure | because humans have a hard time distinguishing between 2 million things and 1 billion things | 11:23 |
delinquentme | so what you're trying to say is theres only about 500 million things that can go wrong | 11:33 |
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kanzure | you could always run a selection project to get something reliably secreted from a cell | 11:34 |
kanzure | but setup for selection projects is often ugh | 11:34 |
kanzure | a good selection project saves a million hours in the library | 11:35 |
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delinquentme | kanzure, you're thinking this is transient or genomic integrated vector ( in the selection project ) | 12:10 |
delinquentme | you're saying that the selection is just lots of permutations on all the different genetic components to get high expression | 12:10 |
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kanzure | eh more like "be creative about ways to use bruteforcing and mutation to your advantage to get transmembrane protein channels for pumping out your desired molecules" | 12:13 |
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delinquentme | large scale screening in something like this would be handy ... like take an input sequence .. get it secreting. change shit in the different parts of that sequence then see what changes in the expression | 12:19 |
delinquentme | slash secretion | 12:19 |
delinquentme | that would give us a really solid mapping of what influences or prevents secretion | 12:20 |
kanzure | there's many different existing secretion systems | 12:20 |
kanzure | a few of them work by just attaching some random linker protein to your target, and it poops out no problem | 12:20 |
kanzure | unfortunately i forget the names of these secretion systems and you'll have to pester yashgaroth | 12:20 |
kanzure | (although there's probably no secretion system that works for all possible targets) | 12:21 |
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kanzure | generic distributed systems book from stripe http://book.mixu.net/distsys/intro.html | 12:41 |
kanzure | "live interactive grep of linux kernel source code" http://livegrep.com/search/linux | 12:42 |
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kanzure | "That's... a bizarre argument. You might as well argue that since heavier-than-air-flight is a search problem over an effectively infinite, high-dimensional landscape of possible machines - and that since it took evolution billions of years to produce birds, we have little chance of stumbling upon a working design for a wing." | 12:44 |
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Etman | hi | 16:27 |
kanzure | greetings | 16:27 |
Etman | how are they? | 16:30 |
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kanzure | alright | 16:38 |
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kanzure | multi-chain payment channel network stuff http://lists.linuxfoundation.org/pipermail/bitcoin-dev/2015-September/010909.html | 17:07 |
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kanzure | yashgaroth: delinquentme is interested in clever secretion systems | 17:17 |
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rancyd | hi all | 17:18 |
kanzure | greets | 17:19 |
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yashgaroth | well he appears to be out so I'll just chillax here | 17:21 |
rancyd | is the wiki a component of cgit? | 17:22 |
kanzure | wiki is a git repository | 17:24 |
kanzure | cgit displays git repositories | 17:24 |
kanzure | github also displays repositories: https://github.com/kanzure/diyhpluswiki | 17:25 |
rancyd | gotcha, what software are you using for the wiki? im just curious because i am setting up a site myself that really just needs a multiuser wiki and git server/browser, and yours seems very minimalist which is nice | 17:31 |
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kanzure | ikiwiki | 17:32 |
kanzure | whole thing is piny | 17:32 |
kanzure | http://piny.be/ahl/architecture/ | 17:32 |
rancyd | oh cool, thank you | 17:32 |
kanzure | wait, that's not the right wiki | 17:33 |
jrayhawk | http://piny.be/ | 17:35 |
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rancyd | do you deploy piny on your own server? | 17:37 |
kanzure | yes piny is running on that server | 17:41 |
rancyd | cool, thanks for the info | 17:44 |
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jrayhawk | http://piny.be/piny-code/docs/install_notes.txt my documentation on it is sort of bad because i am the only person who has thusfar deployed it, AFAIK | 17:50 |
jrayhawk | that said, it is used all over the place, including for freedesktop.org | 17:50 |
rancyd | oh nice, that looks really helpful | 17:52 |
rancyd | did you happen to test with jessie at all? | 17:54 |
jrayhawk | That's a good question. I think there were some brief problems with mod-auth-pam and mod-auth-sys-group packaging; let me go see if any of those installs are up to date... | 17:56 |
rancyd | k, thnx | 17:57 |
jrayhawk | So I don't currently have any fully functioning jessie deployments, but it looks like okay, looks like the functionality for libapache2-mod-auth-sys-group has been replaced by libapache2-mod-authz-unixgroup, so I don't forsee major problems other than that. | 18:01 |
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jrayhawk | s/looks like okay, // | 18:02 |
jrayhawk | I think I last tested jessie back when the apache 2.2->2.4 transition was going on. | 18:02 |
jrayhawk | jessie-or-equivalent-sid | 18:03 |
jrayhawk | oh, i don't have instructions for suexecing cgit, there | 18:06 |
jrayhawk | ugh | 18:06 |
jrayhawk | documentation is hard | 18:06 |
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rancyd | hm, okay i should be able to figure that out. i like documentation, i will probably document my efforts if succuessful | 18:08 |
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jrayhawk | Apache actually makes privilege separation bafflingly difficult; I had to shim suexec with https://secure.piny.be/cgit/insecuresuexec/ to get cgit working with e.g. core.sharedrepository=0660 or 0640 | 18:11 |
jrayhawk | but if you aren't running any such repositories, you don't need to care | 18:11 |
jrayhawk | privilege separation is sortof a good idea if you're in a shared execution environment anyway, what with apache handling pam credentials. | 18:13 |
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kanzure | "The success of fixed wing aircraft is not an ideal metaphor for the failures of AI research. Nor do the successes of neural nets herald the biomorphic approach, since they don't really resemble the brain very much." | 18:16 |
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rancyd | gotcha, thanks again jrayhawk | 18:25 |
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abetusk | kanzure, where is that quote from? | 18:31 |
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kanzure | abetusk: https://news.ycombinator.com/item?id=10165586 | 18:34 |
kanzure | but poor thread comments, is very ugh | 18:34 |
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kanzure | hi zamanfou | 19:22 |
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kanzure | bloop | 21:01 |
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justanotheruser | bleep | 21:06 |
heath | boom | 21:08 |
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kanzure | "bonded deployment" and rollout of bips to avoid soft-fork bit exhaustion or soft-fork bit meaning confusion http://bitcoinstats.com/irc/bitcoin-dev/logs/2015/09/04#l1441334584.0 | 21:19 |
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--- Log closed Fri Sep 04 00:00:00 2015 |
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