| --- Log opened Wed Sep 30 00:00:43 2015 | ||
| nmz787 | .title http://croco.freeonsciencelibraryguide.com/view.php?id=444459 | 00:01 |
|---|---|---|
| yoleaux | TITLE - Libgen Project - Free Internet Library | 00:01 |
| nmz787 | Optical Design of Microscopes (SPIE Tutorial Text Vol. TT88) (SPIE Tutorial Texts) by George H. Seward | 00:01 |
| nmz787 | "There is an excellent book available from SPIE that contains several "recipes" for modelling objective lenses in Zemax, including a full Nikon TIRF objective:" | 00:01 |
| nmz787 | the image on pg 26 is pretty telling (cross-section of objective lense) http://www.iap.uni-jena.de/iapmedia/Lecture/Advanced+Optical+Microscopy1365976800/AOM_Advanced+Optical+Microscopy+Lecture+1+Optical+system+I.pdf | 00:38 |
| nmz787 | (of complexity to mfg) | 00:39 |
| nmz787 | springs! | 00:39 |
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| archels_ | "Those limits suggest that if we had just a laptop sized computer in that time frame, that computer just by itself, in other words containing inside itself one virtual world, that virtual world would have enough detail to not only simulate the whole Earth, but also simulate the brains and everything that’s going on in humans, down to the atom, for everybody that’s now living on Earth." | 01:31 |
| archels_ | Philip Rosedale is an uploader. cool | 01:32 |
| archels_ | (chap behind Second Life) | 01:32 |
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| pasky | fenn: his personal fate is relatively unimportant for these guys, who want to get a point across to the general public instead | 02:14 |
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| fenn | "The Minnesota Multiphasic Personality Inventory (MMPI) is a highly validated psychopathology test that is generally used in a clinical psychology setting and may reveal potential mental health disorders. However, this can be considered by the Equal Employment Opportunity Commission as the employer having knowledge of a medical condition prior to an offer of employment. This is an illegal basis | 03:04 |
| fenn | for a hiring decision in the United States." | 03:04 |
| archels | kanzure: so should I have a couple dozen litres of my blood frozen for when I'm 80? | 03:41 |
| kanzure | yep, also some sperm and teeth and other stuff | 04:23 |
| kanzure | if you can find it, your placenta or umbilical cord would also be good | 04:25 |
| * justanotheruser checks storage drawer for placenta | 04:26 | |
| kanzure | nick barone is asking for criticism about the syringe-injectable electronics idea from earlier this year https://www.facebook.com/nick.barone.775/posts/10100325510441436 | 04:33 |
| kanzure | the primary criticism that i remember is something about manufacturability | 04:34 |
| fenn | does it kill nearby neural tissue like other solid electrode arrays | 04:51 |
| fenn | seems like it would | 04:52 |
| fenn | also i don't see why "roll it up so it fits in a needle" is groundbreaking research in 2015 | 04:52 |
| fenn | could have been done in the 1920's | 04:53 |
| kanzure | what was the mesh type that you liked? | 04:54 |
| fenn | carbon nanotube somethin somethin | 04:54 |
| fenn | flexible | 04:54 |
| fenn | maybe this? http://link.springer.com/article/10.1007/s10544-013-9804-6 | 04:54 |
| fenn | .title | 04:55 |
| yoleaux | All-carbon-nanotube flexible multi-electrode array for neuronal recording and stimulation - Springer | 04:55 |
| fenn | no it wasn't that | 04:55 |
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| fenn | .title http://iopscience.iop.org/article/10.1088/1741-2560/10/4/046016 | 05:02 |
| yoleaux | fenn: Sorry, that command (.title) took too long to process. | 05:02 |
| fenn | pff now i can't even load the page | 05:04 |
| kanzure | someone should try to make a patch clamp microarray at some point | 05:04 |
| fenn | "A carbon-fiber electrode array for long-term neural recording" | 05:04 |
| kanzure | also, not all neural interfacing devices need to work with action potentials, instead once we figure out methylation and engrams or whatever we could just have neural devices that work solely on those molecules after patching in through the cell membrane | 05:04 |
| fenn | "a 16-channel electrode array consisting of carbon fibers (<5??m diameter) individually insulated with Parylene-C and fire-sharpened. The diameter of the array is approximately 26??m along the full extent of the implant. ... provided stable multi-unit recordings over time-scales of months. (in zebra finches)" | 05:05 |
| fenn | what is an "engram" | 05:05 |
| kanzure | just some bullshit about trying to find how memory is stored | 05:05 |
| kanzure | we can get multi-month recording with the other kind of microelectrode arrays | 05:05 |
| fenn | who the fuck decided to make a greek letter the SI unit of 10e-6 | 05:07 |
| kanzure | also, one of the synthetic biology or igem tricks that i have been seeing more of recently are things like "make a reporter gene or intermittent reporting signal based on a genetic circuit with a clock" where a small oligo is synthesized with some reporting information (actually i haven't looked into this to see how it works, because it sounds partly impossible). you wouldn't get realtime data logging but you could get some relative ... | 05:08 |
| kanzure | ... timing information about important metabolic events. | 05:08 |
| fenn | is this the DNA ticker tape idea? | 05:08 |
| kanzure | no idea, only saw this idea out of peripheral vision and didn't look | 05:09 |
| kanzure | haven't completed my summarization of igem 2015 projects http://diyhpl.us/wiki/dna/projects/#igem-2015 | 05:10 |
| kanzure | "Bacillus amyloliquefaciens" really? | 05:11 |
| fenn | i don't know why this nanotube electrode array article isn't in the logs, maybe those logs are missing | 05:16 |
| kanzure | wrong timeline | 05:16 |
| fenn | dammit | 05:17 |
| kanzure | also there was one about folding up into capillaries | 05:19 |
| kanzure | "It has been proposed [1, 2] that a multitude of nanowire electrodes introduced into the central nervous system through the vascular system to address any brain area may be a possible solution." http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092556/ | 05:21 |
| kanzure | (but this was using nanowire) | 05:21 |
| kanzure | "Response of brain tissue to chronically implanted electrodes" (2005) http://nanoforneuro.com/wp-content/uploads/2010/05/reichert_jneurometh_2005.pdf | 05:21 |
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| kanzure | 05:52 < Khoth> Yeah, it's just my pet peeve of people saying supentelligence when they mean wizard | 06:13 |
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| archels | could someone refer me to a good book (chapter) on quaternions that is not terrible | 07:42 |
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| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=9e1af942 Bryan Bishop: transcript: zero knowledge probabilistic proof systems >> http://diyhpl.us/diyhpluswiki/transcripts/simons-institute/zero-knowledge-probabilistic-proof-systems/ | 08:40 |
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| kanzure | "evolutionary biology bootcamp" https://www.youtube.com/playlist?list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu | 08:56 |
| kanzure | "workshop on computational theories of evolution" https://www.youtube.com/playlist?list=PLgKuh-lKre12Ye8BCdtvUt9PdPeIcsbB9 | 08:57 |
| kanzure | "what limits the efficiency of natural selection?" https://www.youtube.com/watch?v=QdwR9huqrUI&index=6&list=PLgKuh-lKre12Ye8BCdtvUt9PdPeIcsbB9 | 08:57 |
| kanzure | "Interaction-based Evolution: How Natural Selection and Non-accidental Mutation Work Together" https://www.youtube.com/watch?v=sryJPgP7ab4&index=7&list=PLgKuh-lKre12Ye8BCdtvUt9PdPeIcsbB9 | 08:57 |
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| kanzure | "some questions from a condensed matter physicist" (on computational theories of evolution) https://www.youtube.com/watch?v=qpcaMHXFCHg&index=26&list=PLgKuh-lKre12Ye8BCdtvUt9PdPeIcsbB9 | 08:59 |
| kanzure | mathematical models in population genetics https://www.youtube.com/watch?v=qpcaMHXFCHg&index=26&list=PLgKuh-lKre12Ye8BCdtvUt9PdPeIcsbB9 https://www.youtube.com/watch?v=KO3-6ntkg9w&index=4&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu https://www.youtube.com/watch?v=f-BiaQrZ8bg&index=5&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu | 09:00 |
| kanzure | "computational views of evolution" https://www.youtube.com/watch?v=YwMiODT5qPU&index=13&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu https://www.youtube.com/watch?v=XFXRApGW_Lw&index=14&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu | 09:00 |
| kanzure | "experimental evolution" https://www.youtube.com/watch?v=FOX3LVvlHAk&index=17&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu https://www.youtube.com/watch?v=JIKnyHMr70E&index=18&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu | 09:00 |
| kanzure | "statistical physics views of evolution" https://www.youtube.com/watch?v=9Th6qMLtJsU&index=19&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu https://www.youtube.com/watch?v=PcKD9PM9rw4&index=20&list=PLgKuh-lKre101KqCYF6EvtQAqiU3qVoAu | 09:01 |
| kanzure | "genetic diversity in the interference selection limit" https://www.youtube.com/watch?v=lf9F-1xgJzc&index=3&list=PLgKuh-lKre12z2B6q_wq__TZeQY_L2jYi | 09:01 |
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| gnusha | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=55dfed5c Bryan Bishop: some more simons-institute videos >> http://diyhpl.us/diyhpluswiki/transcripts/simons-institute/todo/ | 09:21 |
| archels | hm what was that LW post about waging on the side of being pro-transhumanism, or a future omnipotent AGI is going to torture your uploaded resurrections till the end of time? | 09:22 |
| kanzure | .title https://www.reddit.com/r/amateurradio/comments/3mvrv7/interstellar_communications_using_gravitational/ | 09:25 |
| yoleaux | Interstellar communications using gravitational lensing to get >100 dB gain... : amateurradio | 09:25 |
| kanzure | archels: probably something something berserker | 09:25 |
| kanzure | "a paper about gravitational lensing allowing for interstellar communication with only a few milliwatts(!) of power." | 09:25 |
| kanzure | http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.188.1145&rep=rep1&type=pdf | 09:26 |
| kanzure | "is there a non-oil-based tech tree?" https://www.reddit.com/r/PostCollapse/comments/3mlwd8/is_there_a_nonoil_based_techtree/ | 09:29 |
| fenn | lewis dartnell's entire book is about that | 09:32 |
| fenn | heh of course eleitl mentions it | 09:33 |
| fenn | i don't recommend reading "the knowledge" it glosses over all the important details like how to actually DO anything | 09:34 |
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| kanzure | "umbilical cord prolapse" wtf | 10:05 |
| kanzure | in gastroschisis the intestines just protrude through a hole in the stomach, and that's how nutrition happens. cool. | 10:07 |
| kanzure | oops i mean omphalocele | 10:07 |
| kanzure | hm that's not helpful | 10:09 |
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| kanzure | "including omnipotent beings in your threat model is not okay" | 10:23 |
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| kanzure | http://www.loxap.com/programming-libraries-for-chemistry-scientists-w-12030/ | 10:49 |
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| kanzure | https://soundcloud.com/dj-mindflash/dj-mindflash-higher-dimensions-009-january-2015 | 11:18 |
| maaku | kanzure: frustrating that the ABINIT package doesn't do ab-initio simulation.. | 11:18 |
| kanzure | upverter claims to have implemented and rolled out constraint satisfaction stuff for circuits | 11:20 |
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| kanzure | and an on-premise version of their eda stuff. | 11:21 |
| kanzure | maaku: obv. you should be using VESP | 11:30 |
| kanzure | no wait.. | 11:30 |
| kanzure | gromacs, lammps, nanodynamics, uh.. | 11:32 |
| kanzure | fucking hell it was VASP not VESP | 11:32 |
| kanzure | https://en.wikipedia.org/wiki/Vienna_Ab_initio_Simulation_Package | 11:32 |
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| kanzure | and gamess but i don't think this is what i mean either. | 11:34 |
| kanzure | i have a VASP person that you can bug if you want | 11:34 |
| kanzure | oh seems you already know VASP things because of toolset paper | 11:35 |
| kanzure | 17:26 < eudoxia> I always found it hilarious how SIAI got millions of dollars in donations and has not produced a single tangible thing while Merkle and Freitas are probably starving to death under abridge holding up a sign that says "Wil | 11:35 |
| kanzure | l do VASP simulations for food" | 11:35 |
| kanzure | also these lists are still good https://en.wikipedia.org/wiki/List_of_software_for_molecular_mechanics_modeling and https://en.wikipedia.org/wiki/List_of_quantum_chemistry_and_solid-state_physics_software | 11:36 |
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| maaku | yes although for some reason my memory was they used GAUSSIAN for much of that | 12:41 |
| maaku | my memory is fualty it seems | 12:41 |
| kanzure | wrong timeline | 12:42 |
| maaku | (if you recall my goal with the AGI stuff is to make something that can learn efficient approximations then hook it up to VASP) | 12:42 |
| kanzure | have you ever noticed shifting into another timeline/reality where things are almost exactly the same except for minor differences | 12:43 |
| kanzure | like certain technology seems to be missing | 12:43 |
| maaku | i believe there is a whole subreddit devoted to that | 12:43 |
| maaku | for me it just shows how messed up our brains can be | 12:44 |
| kanzure | this is why i have started memorizing hplusroadmap log hashes | 12:44 |
| FourFire | kanzure, uhh I half noticed something like that a few times so far | 12:45 |
| FourFire | I'm not very observant though | 12:45 |
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| delinquentme | TIL hackintoshes have batterly life issues | 13:23 |
| delinquentme | seems ubuntu on MBP hardware isnt going to be happy | 13:23 |
| delinquentme | unless im the one making it happy | 13:23 |
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| kanzure | delinquentme: carry backup batteries etc | 13:27 |
| kanzure | .title https://news.ycombinator.com/item?id=10306204 | 13:28 |
| yoleaux | Why Aren’t America’s Shipping Ports Automated? | Hacker News | 13:28 |
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| * bbrittain looks around | 13:29 | |
| delinquentme | kanzure, funny | 13:30 |
| kanzure | bbrittain: greetings | 13:30 |
| bbrittain | long time, no type | 13:31 |
| bbrittain | I was traveling all sumer | 13:31 |
| kanzure | what about the internship/job/thing? | 13:31 |
| bbrittain | It was alright, considering going back after a finishing up my school | 13:31 |
| bbrittain | kinda doing that job looking thingy | 13:32 |
| kanzure | how was it? | 13:32 |
| kanzure | or what did you do or not do | 13:32 |
| bbrittain | kanzure: the internship/job? I'm not sure I'm supposed to talk about a lot of it. | 13:34 |
| bbrittain | hence one of my reasons I'm considering not going back | 13:34 |
| kanzure | too much secrecy? | 13:35 |
| bbrittain | yup | 13:35 |
| kanzure | see pm | 13:35 |
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| kanzure | hello jakesyl | 15:22 |
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| jrayhawk | Cheaper ZMW/SMRT sequencer released today: http://blog.pacificbiosciences.com/2015/09/introducing-sequel-system-scalable.html | 16:37 |
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| jakesyl | hello kanzure | 18:03 |
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| kanzure | "Hunkapiller" man i bet the yahoo groups users go apeshit over him | 18:32 |
| kanzure | not sure where you are seeing price | 18:32 |
| JayDugger | Good evening, everyone. | 18:50 |
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| JayDugger | Was yesterday's hash 0caa20b54ec2aea1d0d57fc5bbff8e24? | 18:52 |
| kanzure | http://www.scientificamerican.com/article/gene-edited-micropigs-to-be-sold-as-pets/ | 18:53 |
| kanzure | "On September 23, at the Shenzhen International Biotech Leaders Summit in China, BGI revealed that it would start selling the pigs as pets" | 18:54 |
| kanzure | quite the pivot for bgi | 18:55 |
| JayDugger | "Jeantine Lunshof, a bioethicist at Harvard Medical School in Boston, Massachusetts, who describes both as 'stretching physiological limits for the sole purpose of satisfying idiosyncratic aesthetic preferences of humans'" | 18:56 |
| JayDugger | Huh. I will guess that woman's never been to a dog show or a livestock auction. | 18:57 |
| kanzure | or dated | 18:57 |
| JayDugger | Heh. Better point. | 18:57 |
| kanzure | followed naturally from "livestock auction" | 18:58 |
| JayDugger | Fair enough. I wonder if those smaller pigs would make more efficient livestock. Fodder-to-salable meat ratio? | 18:59 |
| JayDugger | Less bone, anyway; smaller pens; pork's a popular meat, and they seem to breed fairly true. Are these little pigs much bigger than rabbits? | 19:02 |
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| JayDugger | maaku, do you remember what subreddit you meant with "i believe there is a whole subreddit devoted to that" yesterday? That sounds like a useful resource for a writing project of mine. | 19:18 |
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| maaku | JayDugger: https://www.reddit.com/r/Glitch_in_the_Matrix/top/ | 19:28 |
| maaku | or this: https://www.reddit.com/r/glitchinthematrix | 19:29 |
| maaku | there's a few actually | 19:29 |
| JayDugger | Thank you for the links. | 19:31 |
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| nmz787 | well, it's not a pickup truck, but with a lift kit... what a dream offroad machine (as long as you don't flip it) http://www.theverge.com/2015/9/30/9421719/tesla-model-x-bioweapon-defense-mode-button | 20:50 |
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| maaku | JayDugger: I've got personal experience of the opposite occurance -- vivid premonitions which come true | 21:22 |
| kanzure | "Sooam Biotech is the only lab in the world that makes genetically identical copies — clones — of dogs for pet owners." | 21:22 |
| kanzure | i wonder if they are suing everyone else | 21:22 |
| kanzure | from http://www.npr.org/sections/health-shots/2015/09/30/418642018/disgraced-scientist-clones-dogs-and-critics-question-his-intent | 21:23 |
| maaku | except what I know to be actually happening is memories rewriting themselves so that I remember my present experience as if i dreamed it before ... memories are funny things | 21:23 |
| maaku | kanzure: i would be very interested to hear those owner's opinions of how similar/dissimilar their cloned pet's personalities are | 21:23 |
| maaku | ok mildly interested. it'd be unreliable data | 21:24 |
| kanzure | negative opinions would seem less unreliable | 21:24 |
| kanzure | "nothing like the original, spends way too much time on my lap" etc | 21:25 |
| maaku | right | 21:25 |
| kanzure | "other dogs visibly confused by resurrection" | 21:26 |
| kanzure | (although a bunch of the smells and scents are partly caused by microbial content, so i doubt the confusion would be there) | 21:26 |
| kanzure | i wonder if you could grow a fungus in an open-air petri dish that would reduce semiconductor manufacturing contamination in filtered facilities | 21:29 |
| kanzure | only works if dust floats by your organism... too bad. | 21:30 |
| kanzure | what are we down to these days, 1 part contaminant per trillion? | 21:31 |
| nmz787 | paul stamets recommends mycelial mats for water filtration... so I imagine something like that would work for air | 21:44 |
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| --- Log closed Thu Oct 01 00:00:44 2015 | ||
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