| --- Log opened Mon Oct 12 00:00:54 2015 | ||
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| kanzure | nope i don't think so | 05:05 |
|---|---|---|
| kanzure | someone took it? or something | 05:05 |
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| kanzure | https://www.reddit.com/r/DebateAnarchism/comments/3o95oo/anarchotranshumanist_ama/ | 05:30 |
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| kanzure | wat "Transhumanists Against Zoltan Istvan Candidacy for US Presidency - A Petition" | 05:31 |
| kanzure | from https://www.reddit.com/r/anarchotranshumanist | 05:31 |
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| kanzure | http://transhumanity.net/i-quite-the-usa-transhumanist-pary-why-zoltans-non-inclusive-leadership/ | 05:33 |
| kanzure | right.. well, whatever. | 05:33 |
| kanzure | alright that's enough of the clown circus for me today | 05:33 |
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| kanzure | "A chimeric prokaryotic pentameric ligand–gated channel reveals distinct pathways of activation" http://jgp.rupress.org/content/146/4/323.abstract | 06:42 |
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| gnusha_ | https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=49479552 Bryan Bishop: fix minor typo >> http://diyhpl.us/diyhpluswiki/transhumanism/ | 07:19 |
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| delinquentme | seriously. where the fuck does someone get high quality cracks without the trojans? | 08:45 |
| delinquentme | I need solid works | 08:45 |
| kanzure | check each checksum hash against site:virustotal.com | 08:46 |
| delinquentme | seems like its an upload / analyst service | 08:47 |
| delinquentme | where checksum go? | 08:47 |
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| kanzure | delinquentme: search with google for checksum against site:virustotal.com | 09:17 |
| kanzure | also, only run solidworks inside of a vm that you're okay destroying later | 09:17 |
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| delinquentme | kanzure, not a bad idea but mehhhh parasitic resources | 09:24 |
| delinquentme | idk | 09:24 |
| delinquentme | you think the vm overhead is worth it? | 09:24 |
| delinquentme | probably . | 09:24 |
| delinquentme | esp since this is a brand fucking new tower + super clean | 09:24 |
| delinquentme | kanzure, | 09:40 |
| delinquentme | i need a stinking windows key for a vm don't i | 09:40 |
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| kanzure | delinquentme: you are a terrible pirate apparently. get the one that doesn't require keys. people have been stripping that stuff out for decades. | 09:53 |
| kanzure | .title http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00465-9 | 09:53 |
| yoleaux | kanzure: Sorry, that doesn't appear to be an HTML page. | 09:53 |
| kanzure | "A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging" | 09:53 |
| kanzure | "Many genes that affect replicative lifespan (RLS) in the budding yeast Saccharomyces cerevisiae also affect aging in other organisms such as C. elegans and M. musculus. We performed a systematic analysis of yeast RLS in a set of 4,698 viable single-gene deletion strains. Multiple functional gene clusters were identified, and full genome-to-genome comparison demonstrated a significant conservation in longevity pathways between yeast and ... | 09:54 |
| kanzure | ... C. elegans. Among the mechanisms of aging identified, deletion of tRNA exporter LOS1 robustly extended lifespan. Dietary restriction (DR) and inhibition of mechanistic Target of Rapamycin (mTOR) exclude Los1 from the nucleus in a Rad53-dependent manner. Moreover, lifespan extension from deletion of LOS1 is nonadditive with DR or mTOR inhibition, and results in Gcn4 transcription factor activation. Thus, the DNA damage response and ... | 09:54 |
| kanzure | ... mTOR converge on Los1-mediated nuclear tRNA export to regulate Gcn4 activity and aging." | 09:54 |
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| delinquentme | kanzure, what search string? | 10:09 |
| delinquentme | " de-keyed" ? | 10:09 |
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| delinquentme | kanzure, not to mention ... how does one verify that the de-keyed operating systems are clean? | 10:13 |
| delinquentme | kanzure, i question your pirateze | 10:13 |
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| kanzure | delinquentme: well, virustotal would be a good place to start, again | 10:14 |
| kanzure | delinquentme: tiny7, black edition, there's lots of options | 10:16 |
| kanzure | wintoolkit kmspico dazloader mstoolkit, etc. etc. | 10:19 |
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| crevasse | http://www.thermofisher.com/order/catalog/product/IVF3001?CID=EM5024752_4_TRANSFAWAREN_20151012 | 10:47 |
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| nmz787_i_ | identify qaz123 | 11:02 |
| nmz787_i_ | stupid nickserv | 11:02 |
| nmz787_i_ | stupid webchat | 11:02 |
| nmz787_i_ | ugh | 11:02 |
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| kanzure | you should change your passwords | 11:04 |
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| kanzure | maybe use lastpass/1pass | 11:07 |
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| nmz787_i | I don't really see the point of an IRC password | 11:17 |
| nmz787_i | but yes, now I need to find another stupid password | 11:18 |
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| kanzure | "Invivofectamine® 3.0 Reagent is an animal origin-free lipid nanoparticle designed for high efficiency in vivo delivery of siRNA and miRNA to mouse liver cells following tail vein injection." | 11:28 |
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| chris_99 | nmz787_i, played with the spectrometer yet out of interest? | 11:30 |
| nmz787_i | chris_99: hehehe, nooooo.... been working on my photolithography setup to try and get some microfluidics up and running... I was planning to integrate the spectrometer on the end of a microchannel though | 11:34 |
| nmz787_i | also I am still setting up my lab, since bench space is tight | 11:34 |
| nmz787_i | just bought a bunch of wood yesterday for a new table | 11:34 |
| chris_99 | aha cool :), whats the microfluidics stuff for | 11:34 |
| nmz787_i | DNA synthesis stuff | 11:35 |
| chris_99 | ah neat | 11:35 |
| nmz787_i | will start by just making some perstaltic pumps, then add on the spectrometer and see if I can sequence pumping of colored fluids | 11:35 |
| nmz787_i | then add on electrophoresis | 11:35 |
| chris_99 | ooh, are you making your own PSU for electrophoresis | 11:36 |
| nmz787_i | ultimately I want to interface with these nanoporous membranes that I got | 11:36 |
| nmz787_i | not sure, I've thought of it, but I have a nice bench supply already for electrophoresis | 11:36 |
| nmz787_i | I am making a PSU for the lithography laser though | 11:36 |
| chris_99 | mm, i got one too, i used it for testing nixies so far heh | 11:36 |
| nmz787_i | basing it on the eevblog uSupply | 11:36 |
| chris_99 | cool | 11:37 |
| chris_99 | what are you gonna use to move the laser? | 11:37 |
| nmz787_i | got this cheap chinese CNC... it is based on two cdrom trays | 11:38 |
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| nmz787_i | so not the best, but should be good enough to get started | 11:39 |
| chris_99 | oh the J... something thing | 11:39 |
| nmz787_i | NEJE | 11:39 |
| chris_99 | thats the one | 11:39 |
| chris_99 | yeah i've seen them on fleabay | 11:39 |
| nmz787_i | the advertising/docs for it are kind of outrageous... like it says they have a custom power IC... but really they did nothing interesting | 11:40 |
| chris_99 | heh | 11:40 |
| nmz787_i | IC as in, they took an arduino, two easydrivers, and a ULN2003 and mounted them all together with a power jack on a single PCB | 11:43 |
| chris_99 | hehe | 11:43 |
| nmz787_i | and some crap about 'low light auto somethingrather'... but really they just meant the laser is always on just enough to appear as a visible spot (that won't burn/etch) for positioning your items to etch | 11:45 |
| chris_99 | i read it's only etches @ 512x512 points or something? is that right | 11:47 |
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| nmz787_i | hmm, I'm not sure... the travel is 38mm x 38mm | 11:59 |
| nmz787_i | and it is supposed to have 0.1 or 0.01 mm resolution | 11:59 |
| nmz787_i | but who knows if that is true | 11:59 |
| nmz787_i | the easydriver's are supposed to have microstepping settings though | 11:59 |
| nmz787_i | and I don't know what they're set to out of the box | 12:00 |
| nmz787_i | I was able to talk g-code directly to it... found they have GRBL 0.8 (one version older than the latest) | 12:00 |
| nmz787_i | so as soon as I note down the settings I will flash with the newer firmware, which is supposed to be much better in general | 12:00 |
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| chris_99 | oh neat, so you can use on linux properly then | 12:01 |
| nmz787_i | yep | 12:01 |
| chris_99 | this might interest you - https://www.reddit.com/r/electronics/comments/3m1bao/13ghz_oscillator/ i thought it was pretty sweet | 12:02 |
| nmz787_i | oh yeah, cool! | 12:03 |
| archels | oh, I thought that said 13 GHz at first | 12:11 |
| archels | that would have been positively impressive | 12:11 |
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| chris_99 | heh, that would be cool, although even 1GHz is impressive imo | 12:12 |
| chris_99 | from such a simple oscillator | 12:12 |
| archels | the simpler, the better | 12:13 |
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| kanzure | .title https://www.youtube.com/playlist?list=PLAMGx-_sKtpNC82cYwp7aXjS18_WcMq9D | 13:23 |
| yoleaux | IndieBio EU Standalone Pitches - YouTube | 13:23 |
| kanzure | cathal garvey spammed out a link to https://www.reddit.com/r/biostartup/ | 13:24 |
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| kanzure | peer review still isn't automated | 13:37 |
| kanzure | i mean, the process of collecting peer review output, anonymizing the data, etc. | 13:37 |
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| kanzure | bloop | 16:49 |
| Aurelius_Home | bleep | 16:50 |
| nmz787_i | borp | 16:53 |
| Aurelius_Home | is there anything as satisfying as trolling white supremacists? | 16:53 |
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| jrayhawk | .title http://www.sciencedirect.com/science/article/pii/S1750946715001099 | 17:17 |
| yoleaux | Effect of a ketogenic diet on autism spectrum disorder: A systematic review | 17:17 |
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| kanzure | robin hanson is busy writing a book about robot overlords http://www.amazon.com/Age-Em-Work-Robots-Earth/dp/0198754620 | 18:31 |
| kanzure | oh nevermind, this is "popularized" content. | 18:31 |
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| kanzure | i wonder if conehead brains are easier to scan | 19:04 |
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| fenn | nmz787 possibly relevant to your laser adventures http://emergent.unpythonic.net/01444658636 | 20:34 |
| kanzure | someone needs to go back in time and tell 15 year-old me that the rules for getting stuff done with software don't entrely apply to other non-software contexts. | 20:37 |
| fenn | context please | 20:38 |
| kanzure | already forgot the context | 20:39 |
| fenn | 15 year-old you will know | 20:39 |
| kanzure | that was around the time i was attempting to retire from web development projects | 20:41 |
| fenn | a mesa 7i92 is way overkill for this NEJE laser, he probably only used it because of the screw terminals, and a parallel port would work fine | 20:42 |
| fenn | oh it's DB25, nevermind | 20:44 |
| kanzure | i was going to write that irc log analyzer thingy (for this channel), but then i figured the whole ordeal was far too insular for my taste | 20:49 |
| fenn | that's a dumb reason | 20:49 |
| kanzure | are you sure? | 20:49 |
| fenn | yes | 20:49 |
| fenn | you can use the log analyzer on any irc logs, no? | 20:50 |
| kanzure | well yeah but i care even less about other log sets | 20:50 |
| fenn | also, it's a presumably useful tool to organize your data | 20:50 |
| kanzure | feels like navel gazing etc | 20:52 |
| kanzure | also, see various updates to http:/diyhpl.us/wiki/transhumanism (no longer "declaration") and http://diyhpl.us/wiki/hplusroadmap | 20:55 |
| * kanzure sleeps | 20:55 | |
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| @nmz787 | fenn: interesting link. my easydrivers say .com, not .cpm :P mine are 'better' clones | 23:14 |
| @nmz787 | and also my housing is more like a makerbot cupcake | 23:14 |
| @nmz787 | but the white pcb looks to be the same | 23:15 |
| @nmz787 | i was able to determine the grbl version on mine also, to be 0.8 | 23:15 |
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