- **Bootstrapping a distributed package system for open-source biology**: kanzure and fenn discuss the design of “agx-get” (an apt-like tool) and its siblings (agx-make, agx-sim, autospex), debating whether a separate dpkg layer is needed or whether a single CPAN-style mechanism suffices for installing and versioning biological protocols and CAD files.

- **PubGet as instant PDF access to scientific literature**: kanzure highlights http://pubget.com/, a service that returns full-text PDFs directly from PubMed queries, streamlining literature acquisition for DIY-bio and transhumanist research.

- **Planning a physical hackerspace / bio-lab**: kanzure intends to lease a dedicated workshop in Austin to house servers and prototyping equipment, noting that the city’s limited manufacturing liquidation market may push him to source used gear from the northeast US.

- **Ellington Lab internship**: kanzure announces he will start working in the Ellington Lab (http://ellingtonlab.org/) on 1 June, aiming to automate molecular-biology protocols despite still being a high-school student.

- **Critique of molecular-biology protocols as “uncompiled code”**: kanzure links Jeremiah Faith’s essay (http://www.jeremiahfaith.com/thoughts/molBio.html) which argues that current bench protocols are error-prone “scripts” rather than robust, versioned, machine-readable programs.

- **Mesh-networking and community wireless projects**: kanzure points to BootlegTogether (http://syn.cs.pdx.edu/~jsnow/bootlegether.net/), an effort to build a wireless mesh in Aloha, Oregon, as inspiration for resilient, community-run infrastructure.

- **Project Polymath and alternative education models**: newly discovered by kanzure, http://www.projectpolymath.org/ is discussed as a potential collaboration space for accelerated, interdisciplinary learning outside traditional academia.

- **High traffic on personal research portal**: kanzure’s site (http://heybryan.org/webalizer/) logged 150 k hits in one month, partly from buggy xmlHttpRequest loops, illustrating the growing interest in his open-source transhumanist resources.

- **Publishing strategy shift**: kanzure resolves to stop writing “email to nowhere” and instead focus on documentation, blog posts, or polished, media-ready articles to maximize impact and reproducibility of his work.