- Kurzweil’s predictive accuracy is debated; participants note he ignores large swaths of technology and that Clarke’s own forecasts (e.g., 75-m octopus) are even wilder.  
- A lab project is pursuing “amorphous fabrication” via coupled transcription-translation circuits: DNA → mRNA → protein, with RNA-polymerase-based transcriptional switches acting as logic gates/oscillators.  
- Key technical challenge: making genotype and phenotype co-locate without external micro-patterning; proposals include ribosome-display, “writozyme” DNA-synthesizing enzymes, and tethering RNA-polymerase to its RNA product.  
- DNA-origami (Rothemund) and DNA-tile self-assembly are considered as scaffolds for 100 % DNA computers, but reprogrammability and defect tolerance remain open issues.  
- Participants sketch a modular “protein LEGO” concept: standardized, functional protein domains that snap together like black-box parts, avoiding the need for Nobel-level design each time.  
- File-sharing infrastructure discussion lists CoralCDN, distributed hash tables, and current P2P networks as background for resilient open-science data distribution.  
- Cybernetic epistemology is contrasted with decision-/game-theoretic semantics: whether meaning emerges from environmental interaction or from internal utility-maximization models.