- Critique of “Singularitarianism”: participants argue that Kurzweil-style followers treat the technological singularity as unfalsifiable dogma, redefining it endlessly and turning the concept into a quasi-religious meme that risks discrediting legitimate transhumanist research.  
- DIY life-logging experiment: procto outlined a university independent-study project called “Exploring the Exocortex,” planning to record and tag every moment of daily life for a month to train machine-learning models that predict and guide personal behavior better than a calendar can.  
- Warning against exhaustive self-documentation: kanzure and others cited Lion Kimbro’s “How to make a complete map of every thought you think” and the burnout/death of a 12-year practitioner to caution that exhaustive autobiographical tagging is unsustainable and psychologically harmful.  
- Open genomic data sources discussed: ftp mirrors (bio-mirror.net, Japan, Korea, Singapore) were identified as public sources for the entire GenBank release (~1 TB), with debate on how much is unique and how to parse FASTA (.fna) files; bkero noted that BioSQL can preload the full NCBI taxonomy.  
- Perfluorocarbons as artificial blood: bkero raised the idea of using perfluorocarbon liquids (e.g., Fluorinert) for oxygen transport and liquid breathing, linking a 1968 PubMed study on the topic.  
- Cluster-building economics: bkero offered to source quad-core, 4 GB-RAM compute nodes for ≈ $400 each (diskless, onboard video) for DIY bioinformatics clusters, while kanzure reported having built an 8-monitor, 2 TB, quad-core workstation for roughly double that price.  
- Zinc-finger nucleases as a gene-targeting tool: kanzure summarized a seminar showing that engineered zinc-finger nucleases are emerging as a “respectable non-killing alternative” to retroviral vectors for precise genome editing.