- DNA data storage was judged uncompetitive against 200 GB Blu-ray discs and falling SSD prices unless read/write speeds improve dramatically.  
- SKDB (System Kernel Design Base) was proposed as a method to auto-discover closed, self-replicating manufacturing graphs by feeding individual parts into a repository; Charles Michael Collins’ patented “desktop microfactory” was examined but deemed unverifiable without complete CAD and parts lists.  
- Biohacking tool-chain gaps were highlighted: no standardized SNP-genotyping protocol, no forensic DNA “counter-primer” attack workflow, and a call to add Affymetrix chip and next-gen sequencing SNP-calling pipelines.  
- Tissue-engineering status: autologous corneal regrowth works, scaffold-based organ printing and artificial-bladder laminar structures exist, but whole-eye cloning is still impossible.  
- “Interlocking block” manufacturing—Lego-like modular parts to eliminate screws and simplify robotic assembly—was proposed to lower microfactory replication barriers.  
- Portable desktop machining rigs (10 cm³ work volume, 20 k rpm, 50 mm/s feed) were praised, yet open, accurate CAD files and English documentation remain scarce.  
- Key links: OpenCalais semantic-metadata API, seedea open-biotech wiki, molecularassembler.com kinematic self-replicator repository.  
- Mishima’s 2007 paper “Concurrent Design of a Manufacturing System Utilizing a Microfactory” outlines a scalable distributed micro-factory network using PROFIBUS, ControlNet, and WorldFIP.  
- RosettaNet’s new Engineering Information Management Standard and Universal Business Language (UBL) were noted as machine-readable design and invoice formats, while legacy B2B/EDI standards (EDIFACT, TRADACOMS, etc.) were criticized for opaque, FTP-based implementations lacking simple discovery.