• A participant shared an open-source genetic circuit design for inducing female breast growth via engineered bacteria and linked to a personal neuroscience document repository at http://heybryan.org/~bbishop/docs/neuro/.

• The group brainstormed DIY body-modification projects including fingertip magnet implants (noting their degradation over time) and subdermal thermocouple mesh implants for harvesting body-heat energy to power future implants.

• Myostatin inhibition via circular RNAi “lassos” was proposed as a muscle-enhancement route, with the commercial platform behind the technology pointed to at http://www.somagenics.com/platform.html.

• Participants debated the analogy between genetic systems and computer architectures, contrasting RISC vs. CISC design philosophies and the limits of simulating genotype-phenotype mappings.

• A call was made for a “consortium of hackers” to conduct rigorous, university-unaffiliated research and publish high-quality scientific papers under pseudonyms or no names at all.

• Material informatics work was discussed: converting the MatWeb materials database to the open MatML XML standard (http://matml.org/) to enable better open-source engineering tools.

• The channel outlined automated business-generation from supply-chain data—scraping logistics information and using simple scripts to spot and broker arbitrage opportunities among large industrial players.

• Salvaged microwave oven capacitors were noted as capable of being combined into a DIY high-current welder or plasma cutter for welding car frames, with grapes in microwaves inspiring plasma-vortex waste-disposal concepts.

• Laser-programmable polymerase experiments were proposed: evolving a polymerase that writes only adenines under light control, with the long-term goal of multiplexing such polymerases for arbitrary sequence synthesis pending simulation and grant funding.