- A new open-source CAD interoperability workflow was proposed that combines parametric unit checking (via the Python “pq” library) with geometric fit verification to automatically decide whether two arbitrary 3-D models can mate, replacing traditional six-sigma inspection with statistical tolerance propagation.  
- Reeb graphs—skeletons extracted from geodesic-distance scalar fields—were advanced as a fast, metadata-light way to index part similarity and locate potential mating regions, with links to scale-space and augmented-Reeb papers for 3-D retrieval.  
- Participants debated SKDB’s storage strategy: lightweight Reeb-graph descriptors versus full 3-D models, and how to arbitrate among conflicting “evaluation engines” that must verify constraints spanning geometry, manufacturing tolerances, chemistry, and ergonomics (modeled as kinematics plus pressure simulation).  
- A practical assembly pipeline was outlined: (1) threshold a geodesic field to partition a shape, (2) extract boundaries as Reeb-graph nodes, (3) match against interface layers—tagged metadata analogous to RPG map event layers—that declare standard ports (USB, pipe fittings) and fall back to geometric search when standards are unknown.  
- Research links shared include Triangle (CMU Delaunay/Voronoi mesher), Blender harmonic skeleton generation, spherical-histogram shape descriptors, and papers on port-compatibility, assembly constraints, and web-based modular interface geometries.  
- A 3 000-solution dataset (3000FCGs_complete) was described: GraphSynth-generated XML/DSM files with 138×138 connectivity matrices, 1000×1000 distance matrices, and gnuplot visualizations of the 50 most-dissimilar candidates.  
- drazak proposed a reagent-free “lab-on-a-chip” for RNA/protein separation using charge-based filtration and polymerizable zwitterionic detergent (CHAPS) to create in-situ “nanoknives” for cell lysis.