- SkQ1, a mitochondrially-targeted antioxidant developed by Vladimir Skulachev’s lab, was highlighted as a promising intervention against mitochondrial oxidative stress and aging; links to fightaging.org coverage, the Moscow 2010 biogerontology meeting, and Skulachev’s email address were shared.  
- Participants debated why evolution has not produced extremely long-lived animals; Skulachev’s explanation that programmed aging clears ancestral competition and accelerates adaptation was cited as the leading hypothesis.  
- A student (bruns/Bellum) outlined plans to present a “grand vision” of inducing amphibian puberty-reversal to a professor, with kanzure urging a practical first step such as protein isolation and crystallography of the jellyfish gene product.  
- The channel discussed ISO 10303 (STEP) standards, noting that TC184-SC4 uses Bugzilla for issue tracking and that EXPRESS-generated parsers still fail to give useful error messages when fed invalid CAD files.  
- Humanity+ leadership-list access was arranged so that kanzure could circulate details about the Gada Prize judging criteria to the board.  
- DIYBio list culture was criticized for inexperienced commentary; drazak vented frustration while clarifying that #hplusroadmap members were not the offenders.  
- Utopiah pointed the “Software Mindfiles” project to the newly proposed Cognitive Characteristics Ontology (http://smiy.sourceforge.net/cco/spec/cognitivecharacteristics.html).  
- A $30 000 crowdfunding milestone for the BioCurious biotechnology hackerspace was announced via a Medgadget article.