- Prusa is prototyping automated assembly-instruction generation for RepRap printers and teasing an undisclosed “secret project”; kanzure surfaced legacy SKDB code and academic assembly-planning papers as prior art.  
- Lukas___ outlined an experimental program to create protein-based immune suppressants modeled on fetal MHC variants that prevent miscarriage, aiming to enable half-matched tissue grafts without rejection.  
- The Gada Prize ($80 k Grand Prize) is driving secrecy in the RepRap community; kanzure proposed requiring open-source schematics and “no-derivative” clauses to restore transparency and keep the hardware commons open.  
- Channel consensus is that single-molecule “3rd-generation” DNA-sequencing platforms (Oxford Nanopore, PacBio, Helicos, ZS Genetics, Halcyon Molecular, etc.) will deliver $100–$1 000 genomes within 4–10 years, while DIY DNA synthesis remains bottlenecked by 60-nt oligo limits and high error rates.  
- Memristor-based neuromorphic computing was highlighted as a convergent technology that could revive HP’s relevance and transform machine-learning hardware; participants linked IEEE Spectrum’s “Moneta” article and Max Versace’s YouTube channel and compared the approach to Carver Mead’s analog-VLSI work.  
- A DIY circadian-biology experiment was proposed: culture human red blood cells in an incubator/oxygenator to replicate the 2011 Nature finding of 24-hour redox cycles in peroxiredoxins, using temperature-compensation data for PRX2 as a control.  
- The channel debated decentralized-web architectures, criticizing Diaspora and Google Wave while advocating Kademlia-DHT or Freenet-style webs-of-trust; the stalled Netsukuku mesh/DNS project was mentioned as an alternative to centralized DNS.  
- SENS announced a new Mountain View research facility with a public open-house on 6 Feb 2011, circulating a Facebook event link and reinforcing the open-science ethos of the life-extension community.  
- Participants questioned whether professional medical licensing is a legitimate safety mechanism or a rent-seeking cartel, parsing statutory definitions and debating the ethics of “practicing medicine without a license.”