- The #hplusroadmap community maintains a large open-access literature archive at http://diyhpl.us/~bryan/papers2/ covering stem-cell research, longevity science, microfluidics, and other human-enhancement topics.  
- Participants argue that current DIYbio output is “pathetic” and identify open-source microfluidic lab-on-a-chip devices and open CAD/lab-equipment design as the most promising near-term directions for credible biohacking.  
- The $50 k Gada Prize for a self-replicating 3-D printer has moved from Foresight Institute to Humanity+; an estimated 10–15 RepRap teams already have qualifying hardware but withhold open-sourcing to protect potential revenue.  
- A second-hand MegaBACE 1000 capillary DNA sequencer listed at ~$100 on eBay is being evaluated as an entry point for low-cost genomics, despite unknown laser condition and >$1 k reagent costs.  
- STEP/EXPRESS CAD standards (AP203, AP214, AM1001-1009) were obtained without paying the ~$200 official fee; the files will be released publicly after an upcoming Google I/O Austin talk.  
- lepht (Alicia Mason) published a reflective essay on the stagnation of grinder culture; the channel offered permanent hosting on diyhpl.us/gnusha.org to replace the current MediaFire link.  
- flamot released a silent update to his cellular-automata genetic-algorithm simulator “ca-ga 4.99.99” (tinyurl.com/4bqwyb7), claiming 3.3 million neurons, emergent sex and multicellularity, and plans to write a Phrack/2600 article on evolving CAPTCHA crackers before such software is export-controlled as cryptographic munitions.