- Discussion of open-source liquid-handling robot designs: one participant built a low-cost LH001 unit using a peristaltic pump with pull compression (later deemed a “bad idea”), while another is prototyping a three-axis gantry system with linear actuators and glass syringes to cut biotech equipment costs.  
- Accuracy targets mentioned: 0.1 µL dispensing precision and the challenge of achieving repeatable micro-volumes with inexpensive hardware.  
- Novel liquid-handling technologies referenced: Tecan-style sealed-piston pumps, disposable-tip pick-up/drop mechanisms, flow-through tip washing, and high-throughput acoustic droplet ejection (ADE) systems from Labcyte.  
- Debate on how “flow-through” washing can achieve near-sterile conditions between samples without disposable tips, highlighting a knowledge gap in large-volume sterile flushing protocols.  
- Aging-research landscape: Laura Deming (Thiel Fellowship recipient) noted as a visible figure, but participants question whether $100 k is sufficient and ask which labs are applying high-performance computing to longevity research.  
- Proposal for in-silico human metabolic modeling: iterative simulation of drug interactions using known biochemical data to bypass legal/ethical limits on human testing, with emphasis on endocrine feedback loops and multi-drug combinations.  
- Shared resources: GitHub repository for OpenSCAD syntax highlighting in TextMate and the “Inflatable Cookbook” PDF (letsremake.info) circulated as maker-space references.