- A hand-drawn open-source workflow for bench-top oligonucleotide synthesis (http://i.imgur.com/cl7Ng.jpg) was circulated, aiming to slash the cost of DNA primers for biohacking projects.  
- Participants dissected DIY tDCS: an LM334-based, current-regulated open-source schematic (300 Ω pot, cosmetic-sponge electrodes) is being refined on Reddit/r/tDCS, with warnings that electrode placement and safety documentation must accompany any kit sales.  
- A Nature paper on “one genome from many” was highlighted; the UW-Seattle team will release code in ~6 months that reconstructs complete microbial genomes directly from mixed environmental samples, bypassing the 99 % of species that cannot be cultured.  
- A post-doc argued that 3-D printing organs cell-by-cell is hitting viability and vascular limits; his lab is pivoting to rapid-perfusion scaffolds that let cells self-organize into functional tissue instead.  
- Recent biomedical milestones shared: same-day nerve re-attachment, direct reprogramming of human skin cells to neurons without iPSC intermediates, and decellularized pig-heart scaffolds reseeded with human cells.  
- The Russian “Russia 2045” immortality/avatar project (2045.com) was critiqued for omitting prominent Russian transhumanists, while Ray Kurzweil’s Super Bowl ad and Steven Seagal’s endorsement letter were linked as cultural datapoints.  
- Exercise-induced oxidative stress—not antioxidant supplements—was cited as the actual trigger for health benefits, referencing Michael Ristow’s work and data showing long-term antioxidant use correlates with worse cancer and heart-disease outcomes.