- Pyjamas-desktop enables Python desktop apps that embed a web engine; a hidden-iframe/JSON hack is proposed to extract return values from JavaScript in MSHTML, which lacks a native JS-evaluate API.  
- Compiling hulahop (Python-XPCOM bridge) on modern Debian/Ubuntu fails because of mismatched xulrunner 9.x vs. Gecko 2.0 APIs, missing PyXPCOM.h, and hard-coded Python 2.6 dependencies.  
- John Schloendorn’s BIL talk “Garage-Level Biomedical Research Effort Is Taking on Death” is discussed; participants note Thiel funding has moved it beyond “garage-level” and question whether wealthy patrons back the right transhumanist projects.  
- ParahSailin__ outlines a bootstrapping plan for a future lab: start with fee-for-service work (cell-line banking, protein production) instead of grants or “rich fools.”  
- kanzure’s “meetlog” tool (http://diyhpl.us/~bryan/irc/meetlog/) automatically logs every IRC conversation, tags participants, and generates social-graph pages to track who has discussed which transhumanist topics.  
- delinquentme demonstrates OSCAR-4 (Java cheminformatics library) via JPype to parse free-form organic-chemistry prose into machine-readable reaction data, enabling open-source literature mining for DIY chemists.  
- A $0.15 microfluidic cuvette built from acrylic and sticky tape is shared on YouTube as an example of ultra-cheap lab hardware.  
- Cambrian Genomics (San Diego, George Church on advisory board) is discussed for its pivot to oligo synthesis using lasers; the firm’s near-absent web presence is noted.  
- Funding options are compared: Breakout Labs vs. “vampiric” biotech VCs; Y Combinator, TechStars, and AngelList are recommended as friendlier alternatives.  
- Open-access resources posted include plant-transgenics lab manuals (Jones 1995, Loyola-Vargas 2006), the booklet “Science Against Aging,” and Citizen Science Quarterly Volume 01.