- Evolutionary-algorithm–driven analog-circuit design is being revived through an open-source GitHub project (https://github.com/Ttl/evolutionary-circuits) that participants see as an under-appreciated alternative to contemporary ML approaches.  
- A data-driven debate on the U.S. science labor market used BLS statistics ($60 k median for life/physical sciences) and first-hand reports of $28 k–$37 k post-doc salaries to argue that academia exploits an oversupply of Ph.D. labor, with supporting links to NIH “disguised unemployment” studies and a 2010 Chemistry-Blog exposé of 24/7 lab demands at Caltech.  
- The channel is building a garage-scale microfluidics pipeline: a laser-cutter-based prototyping workflow, an annotated literature archive (http://diyhpl.us/~bryan/papers2/microfluidics/), and side-by-side evaluation of fabrication methods ranging from oven-bake lamination and PCB microfluidics to electrowetting-on-dielectric and hand-drawn “sharpie” channels.  
- A live experiment in manual oligonucleotide synthesis is being organized as a low-cost learning project, with plans to collect protocols from an NYC academic who previously performed it as an undergraduate organic-chemistry exercise.  
- Participants concluded that iteration speed, not capital, is the primary bottleneck for open biotech breakthroughs; current funding comes from software-contracting income ($40–$75/hr, $200–$500/day) and is being used to co-locate key contributors and acquire shared equipment (CO₂ laser cutter, microfluidics tools).  
- The DIY transhumanist knowledge base is maintained at http://diyhpl.us/wiki (git://diyhpl.us/diyhpluswiki.git) and now includes an indexed project list (http://diyhpl.us/~bryan/irc/diytranshuman_projects.v4.html) and FBI/DIYbio DNA documentation to support decentralized research.