- Gut-bacteria metabolic engineering: participants proposed creating a probiotic strain that constitutively expresses α-galactosidase to mimic adult lactase persistence and discussed the need for mouse models that over-express tumor-suppressor genes (e.g., p53) and are then exposed to cigarette smoke, hoping the 1000 Cancer Genomes Project will soon yield a short list of genes worth duplicating for systemic cancer resistance.

- Open-access archive: kanzure’s diyhpl.us/~bryan/papers2/ repository was highlighted as a large, curated collection of freely available papers on synthetic biology, microfluidics, longevity research, DNA methods, polymerase work, and neuroscience, with two metabolic-engineering papers on expanding biofuel pathways and enhancing lipid production specifically called out.

- Non-invasive brain stimulation: the 2011 Nature Protocols paper “Ultrasonic neuodulation by brain stimulation with transcranial ultrasound” was circulated to support discussion of phased-array ultrasound emitters for deep-brain targeting; the microwave auditory effect and ultrasound-induced auditory hallucinations were also noted as phenomena reproducible with consumer hardware given firmware tweaks.

- DIY neurostimulation safety and community fragmentation: participants debated whether a true “neutral point” exists between anodal and cathodal tDCS electrodes, planned bilateral parietal stimulation experiments, and discussed NeuroMod’s effort to give away HD-tDCS devices while archiving research on Reddit—prompting concern that open-transhumanist knowledge is becoming siloed across IRC, Reddit, and legacy forums.

- Low-cost tagging and credential leaks: an Alibaba listing claiming RFID stickers at “$0.00000001 each” with 1.2 trillion-unit monthly capacity was dismissed as likely fraudulent but cited as a data point for ultra-low-cost tagging, while a freshly leaked Yahoo password dump (~453 k accounts) was circulated and found to contain mostly already-locked or worthless credentials, illustrating the rapid turnover of leaked data.