- A debate over chronic megadose vitamin C questioned whether it blunts beneficial hormetic oxidative stress, with references to the Perfect Health Diet series on vitamin C recycling and the observation that very-low-carb diets can impair that recycling, leading to dry eyes, ulcers and brain fog unless extra vitamin C, salt and water are supplied.

- Participants framed a shift toward phototroph-based human nutrition—using plants and algae instead of animals—as a transhumanist optimization that could drastically cut methane, manure and energy footprints.

- The channel dissected the viral “Rayfish Footwear” campaign—advertising genetically engineered stingray-skin sneakers in custom color patterns—and concluded it is an environmentalist ARG hoax because the claimed transgenic color-pattern technology does not yet exist.

- kanzure and nmz787 are designing an open-source, micron-resolution laser cutter to replace their ULS-25ER, targeting lead-screw drives with 1/16 micro-stepping for ≈0.16 µm theoretical resolution, while noting that LinuxCNC/GRBL via parallel port may be too slow for the desired cut speeds.

- Synthetic-biology progress was highlighted by an io9 article on new transcription-factor-based genetic circuits that can act as promoters or repressors, described as a step toward fully synthetic human cells.

- Wiley announced that all WileyOpenAccess journals will now use the Creative Commons Attribution (CC-BY) license, removing reuse barriers for open research.

- kanzure linked a Discover Magazine post advocating routine whole-genome sequencing of fetuses as standard clinical practice, and described ongoing work to integrate Zotero’s paywall-bypassing translator scripts into a headless Firefox/PhantomJS setup for the channel’s paperbot.

- TheEmpath shared the PDF “Molecular Biology for Computer Scientists” (Craven & Hunter) as a recommended primer for programmers entering biology.