- A black-market monoclonal-antibody service was proposed to supply hard-to-obtain cancer therapeutics; participants weighed producing full antibodies in mammalian culture versus Fab fragments in E. coli, citing the 2012 fake-Avastin scandal as evidence that $100 k-per-year drugs invite counterfeiters who currently just swap saline.

- A low-power tactile-feedback prototype was shared that replaces pager motors with an ear-bud voice-coil driving a magnet in a tube, with discussion of coil wire gauge, MOSFET drivers, and piezo alternatives for open-source haptic wearables inspired by the Northpaw compass anklet and Paul Bach-y-Rita’s BrainPort tongue display.

- JBEI’s Tecan Freedom EVO liquid-handling robots reportedly idle >50 % of the time because reprogramming protocols is labor-intensive; the open-source “prpr” Python driver (GitHub: JBEI/prpr) and proprietary “j5” library were contrasted with Transcriptic’s drag-and-drop protocol model as possible solutions.

- Gray-market nootropics and bio-supply chains were illustrated with links to medsforbitcoin.com (modafinil/armodafinil) and btcnootropics.com, while Genentech patent peptide sequences for ranibizumab vs bevacizumab were posted to demonstrate community sharing of full V-region data for DIY antibody production.

- Calls for open-source software contributions included refactoring the paywall-circumvention bot paperbot toward a plugin architecture with unit tests and improving pdfparanoia, alongside pointers to the Biocurious projects page and Bosslab’s DIY light-thermocycler as grassroots bio-hardware resources.