• Paperbot, the channel’s automated paper-fetching bot, was patched in real time to fix Sci-Hub cookie handling and contributors discussed turning it into a reusable Python library with an HTML diagnostics page instead of IRC spam.

• A proposal was floated to genetically engineer human hair and nail follicles to synthesize and sequester high-value drugs (e.g., epinephrine) directly into keratinized tissue, creating a built-in, leak-proof emergency medicine depot.

• Participants debated the economics of publicly funded research, suggesting an index that publicly displays the estimated taxpayer cost of each paywalled paper (e.g., “This paper cost you $41,341—now you can’t read it”) to highlight paywall absurdity.

• A “hackathon scam” alert was issued: the Human API event was identified as a corporate ploy to get free labor by requiring all hacks to use a single company’s API and likely surrendering IP rights.

• Open-science infrastructure ideas included prior scripts that first harvested complete journal indexes and then batch-downloaded papers, emphasizing that completeness requires an authoritative index before retrieval.

• Bio-hacking concepts floated for immediate student projects included DIY DNA synthesis, trans-cranial ultrasound, organ perfusion, HPLC, Taq polymerase production, wearable computers, and DIY AFM.

• Discussion referenced recent advances in growing vascularized, functional human liver buds from iPSC-derived organoids and transplanting them into mouse brain or abdomen as proof-of-principle for ectopic organ maturation.

• Continuous blood chemistry monitoring was explored: chemo ports and fistulas offer long-term vascular access but carry infection and biofilm risks; exposed capillary beds (wrist, oral mucosa) were considered for non-invasive sensing.