- A user asked for a “manual” or protocol for mail-ordering a chimeric protein (specifically DRACO) and mass-producing it in E. coli, noting that DRACO fuses a viral-dsRNA-binding domain with a procaspase domain to trigger apoptosis in infected cells and bypass viral defenses.  
- Discussion referenced the DRACO (Double-stranded RNA Activated Caspase Oligomerizer) concept as a potential broad-spectrum antiviral cure, highlighting its modular design that crosslinks on viral dsRNA to induce cell suicide.  
- brmlab.cz’s “brmson/helloqa-prototype-howto” was shared as an open-source question-answering prototype; sample output correctly extracted “three bombs” from a 2005 London bombings paragraph, but the corpus was small and accuracy limited.  
- Paperbot and yashgarothbot successfully retrieved and mirrored paywalled Springer protocols (e.g., 10.1007/978-1-60327-136-3_1) via diyhpl.us and ge.tt, demonstrating continued community use of automated academic-paper sharing tools.  
- A participant sought common household oils suitable as microfluidic carrier phases (e.g., olive or canola oil) for low-stakes testing, emphasizing the need for fluids that do not interact with biological samples.  
- An inquiry about “unofficial” transhumanist channels for fringe or frowned-upon experiments prompted debate on the perceived formality of ##hplusroadmap and the absence of a dedicated “crazy theories” space.