- A Science Translational Medicine paper (DOI 10.1126/scitranslmed.3004685) and several Nature Immunology articles were retrieved via paperbot/libgen, illustrating the channel’s routine use of automated tools to bypass paywalls for research access.  
- seba- proposed an interim, low-cost mantle-cell lymphoma regimen combining curcumin + piperine while awaiting relapse, after which he plans to add ipilimumab, rituximab, and ibrutinib; the group debated the relative merits of anti-CTLA-4, anti-CD20, and small-molecule inhibitors and shared supporting literature (doi:10.1016/j.bbrc.2005.03.098, NCT00113841).  
- A Chinese AliExpress “Cranial Electrotherapy Stimulation” sleep-device manual was OCR-translated and discussed as an example of low-cost consumer neuro-modulation hardware.  
- The economics of scientific funding were debated, contrasting government grants with market-based models; participants cited empirical studies (Jewkes et al.) and libertarian critiques (Cato, Rothbard) while highlighting citation bias, hidden labor costs (£2.2 m, 320 k person-hours for the Historical Thesaurus of English), and tacit knowledge issues in technology transfer.  
- Open-source CAD geometry kernels were compared: OpenCASCADE (400 man-years of NURBS/boolean code but hard to maintain) versus BRL-CAD’s cleaner LGPL NURBS code; kanzure’s python-brlcad project (https://github.com/kanzure/python-brlcad) uses ctypes and may need SWIG to reach newer C++ NURBS routines.  
- CadQuery, a pip-installable Python scripting layer for solid modeling, currently runs inside FreeCAD (OpenCASCADE) and has an experimental branch swapping FreeCAD for pythonocc (SWIG bindings to OCE); FreeCAD auto-generates its Python wrappers from XML via src/Tools/generate.py.  
- Practical maker notes included a GitHub repo for an open-source UV-DLP 3-D printer slicer controller (UVDLPSlicerController) with thermistor lookup tables, a Linux USB-MIDI driver request, and a new Cork BioMakerSpace mailing list (freelists.org/list/corkbiomakerspace).