- A full teardown of the Applied Biosystems 391 DNA Synthesizer was released, offering 8 MP annotated photos and readable chip labels to accelerate reverse-engineering of the instrument.  
- Participants outlined a plan to revive NanoEngineer-1 as a truly open-source nanotech CAD suite by swapping its proprietary atom models for OpenBabel objects, rewriting the GUI in OpenGL, and migrating core logic to plain C for easier cross-language bindings.  
- A new Python “modelo” base class (https://github.com/kanzure/modelo) was introduced as a minimal, extensible foundation for future molecular-model objects, with an immediate task of replacing all print statements with the standard logging module.  
- Gut-microbiome engineering ideas included introducing soil-derived phytase-producing bacteria, cyanocobalamin-converting strains for vegans, and vitamin-synthesizing microbes, while noting that most floral OTUs remain unclassified.  
- A nutritional debate highlighted shellfish (mussels, clams, oysters) as a near-complete micronutrient source capable of closing vegan nutrient gaps, alongside discussion of trans-fats and human metabolic “fragility.”  
- Eric Drexler’s 2014 TVC keynote (http://metamodern.com/2014/07/03/keynote-at-tvc-2014/) was referenced; channel members argued that venues combining nanotech, additive manufacturing, Haskell, and medicine are already common in spaces like this IRC and the ExI list.  
- The neuromorphic hardware lineage was traced via a 2000 Science paper (DOI 10.1126/science.288.5466.669) on “A Silicon Neuron,” showing early CMOS emulation of biological neuron dynamics.  
- A 2014 Human Brain Mapping paper on psychedelics and whole-brain functional connectivity diversity was shared twice, underscoring ongoing interest in pharmacological augmentation and neurodynamics.  
- paperbot, an open community tool that mirrors paywalled PDFs to diyhpl.us, was used repeatedly to fetch ACS Langmuir and other articles, illustrating the channel’s systematic circumvention of academic paywalls.