- A trove of neuroscience papers was pulled via paperbot, covering lurasidone-driven BDNF modulation, oligodendrocyte protection/remyelination in MS, and Parkinson’s mechanisms—evidence of sustained pharmacological cognitive-enhancement and neuro-protection research.  
- Open-source CAD stacks were compared: cadquery (Python wrapper on FreeCAD/OpenCASCADE) and verb-nurbs (JavaScript NURBS kernel) versus STL’s triangle-mesh bloat, highlighting the push for compact, parametric 3-D printing workflows.  
- PX4/Firmware, Pixhawk, and the newly announced Dronecode platform were spotlighted as ready-to-hack open-source UAV autopilot ecosystems.  
- Early-internet archaeology surfaced Keith Lynch’s 1975–1983 SF-Lovers archive and 1990s extropians posts by Wei Dai, Nick Szabo, and Hal Finney, with speculation that an even earlier 1985–1990 list seeded today’s transhumanist/crypto discourse.  
- Security briefings covered the Linux backdoor used in the Freenode compromise and a fresh Windows OLE/PowerPoint RCE vulnerability, underscoring infrastructure-security concerns for open biohacker networks.  
- A LaTeX draft “bitcoin-incentives.tex” (https://github.com/kanzure/bitcoin-incentives) and collaborative gist (https://gist.github.com/kragen/bec6fc042c651d550333) were shared to formalize why miners might forgo transaction fees and whether Bitcoin amplifies Piketty’s r > g inequality.  
- Topology-optimization-driven mechanical design was explored: Campbell’s “A-Design” framework (http://diyhpl.us/~bryan/papers2/campbell/) and Swantner’s 2009 gear-train paper were cited as foundations for automated synthesis using A*, genetic algorithms, and FEM.  
- Participants proposed co-optimizing G-code and part geometry for FDM 3-D printing to minimize print time and overhangs, referencing PARC’s closed-source “ufab” simulator for build-orientation optimization.  
- Interval arithmetic was suggested as a robust 3-D geometry representation for fabrication, with Kragen’s interval-graph code (http://canonical.org/~kragen/sw/aspmisc/intervalgraph.html) offered as a starting point.