- GPU market dynamics: participants noted that high-end GPUs remain scarce and expensive because alt-coin miners continue to buy them, and Scrypt ASICs for Litecoin now exist, keeping demand high.  
- Reverse-engineering tools: kanzure highlighted PEDA (Python Exploit Development Assistance for GDB) with built-in ROP-gadget search and shell-code generation, and shared his own large-scale reverse-engineering projects—open-source re-implementations of Pokémon Red and Crystal.  
- Structured laboratory protocols: the channel debated the lack of machine-readable chemical-synthesis instructions; PubChem and diagram-heavy sites were deemed inadequate, and an old XML PCR protocol was cited as an early attempt at structured lab automation.  
- Open-source protocol repositories: nmz787 asked whether an open-source “Instructables for science” exists; kanzure replied that only limited OCW-style MOOC resources are available and pointed to the SKDB documentation for hardware-package metadata.  
- Immune-system reboot concept: a long quote argued that instead of mapping the immune system’s complexity, research should focus on gentle, chemotherapy-free methods to wipe and re-seed a patient’s immune cells from their own stem cells.  
- Memory augmentation research: kanzure linked a USENIX Security ’14 paper describing how spaced-repetition techniques can reliably store 56-bit secrets in human long-term memory.  
- Hardware trending: kanzure observed that Verilog projects are trending on GitHub and posted an OpenCores VHDL implementation of the Bitcoin double-SHA-256 core.  
- Cryptographic education: a Chain.com blog post explaining the elliptic-curve math behind Bitcoin signatures was shared for those interested in ECDSA internals.