- A 2013 optogenetics paper titled “Optogenetic rendering of a whisker space holodrome with single-spike precision” was linked, prompting discussion of the term “holodrome” as a 3-D sensory map for whisker input.  
- The SynBioBeta 2014 year-in-review was shared, summarizing trends and milestones in synthetic biology.  
- A critique of modern biology was posted: it argues that the field has drifted from foundational theoretical questions toward trend-driven “glamour journals,” contrasting the early quantitative genetics work of Fisher, Wright, and Haldane.  
- A Bekenstein-bound thought experiment compared DNA storage (≈5.6 × 10¹⁵ bits per gram) with the theoretical maximum for matter of the same volume (≈1.6 × 10³⁸ bits), highlighting the vast gap between biochemical and physical limits.  
- Discussion of secure-shell hardening referenced the blog post “Secure Secure Shell” (stribika.github.io) and the need for an SSH “--really-secure” mode that disables weak algorithms.  
- A Wassenaar Arrangement overview was requested, framing it as a multilateral export-control regime affecting dual-use technologies.  
- kanzure floated the idea of a cloud MEMS foundry service analogous to Transcriptic’s biology platform.  
- Intel’s new “Compute Stick” HDMI-plug computer was announced and linked on Hacker News.