- A web-based GPU-accelerated PCA service is under development that will add automated model-selection, and its creator is simultaneously benchmarking NVIDIA Jetson TK1 power efficiency for Bitcoin mining in an upcoming Make magazine article.  
- Participants debated high-impact human germline edits, endorsing adult lactase persistence while proposing restoration of the GULO gene for vitamin-C synthesis and introduction of the *E. coli* phytase gene (already used in Enviropig) to improve phytate digestion.  
- The channel circulated security resources including an Android CVE-2014-7911 privilege-escalation analysis, an introduction to Sigreturn-Oriented Programming, and a Dagstuhl seminar report on machine-learning approaches to computer security.  
- A ScienceDirect paper claiming the ribosome is a “missing link” in the origin of life was retrieved, though participants noted the authors’ stated GenBank submission (KP006601) appears nonexistent.  
- Discussion emphasized the need for human metabolic systems to tolerate small variations without systemic collapse, framing metabolic robustness as a key design constraint for future enhancements.  
- MTHFR polymorphisms were argued to have larger health impacts than lactase variants, shifting attention toward folate metabolism as a high-leverage target for DIY genomics interventions.  
- The group explored achieving precise, optogenetically switchable control over inflammatory pathways—programming the timing and location of inflammation rather than blanket suppression—as a next-generation therapeutic strategy.