• The channel is prototyping an open-source “DNA printer” that couples a 192-nozzle Epson inkjet head (6–10 pL droplets) to a LinuxCNC motion stage, aiming to synthesize 1–100 million bases for < $10 k while keeping reagents under 200 ppm H₂O in a nitrogen-purged chamber.  
• Workflow design: inkjet microarray DNA synthesis → optical QC (absorbance or sequencing) → Gibson assembly → PCR amplification → bacterial transformation with GFP screening, all on standardized, robot-shuttled sample trays to eliminate manual handling.  
• Hardware stack: Mesa FPGA Ethernet card ($59) drives inkjet analog drivers; stepper-belt stages replace costly Parker units; inspiration drawn from Transcriptic’s robotic molecular-biology line and prior gantry-robot DNA bag shuttling.  
• DIY oligonucleotide chemistry discussion emphasizes cloning proven protocols (ABI 391, POSAM manuals v1-2 & v1-4) and sourcing ultramild phosphoramidites from Azco Biotech and Glen Research; error rates compound exponentially for 80-bp constructs flanked by 20-bp primers.  
• Single-molecule imaging links shared: 2015 AFM paper on DNA secondary structure, EM/AFM galleries showing seven-strand “cords” needed to withstand beam damage, and a biology-focused AFM webinar playlist.  
• Parallella’s 16-core Epiphany chip ($99) dismissed as unreliable demo hardware; praised conceptually for SRAM mesh architecture that eliminates cache-coherency overhead, but incompatible with existing x86/Linux software stacks.  
• Bitcoin governance crisis: Gavin Andresen’s Bitcoin XT 8 MB → 1 GB block-size fork labeled reckless, risking accidental hard-fork; wallet security debates cover Shamir secret sharing, P2SH multisig (2012), and LibreSSL’s incompatibility with Bitcoin Core.  
• Cambrian Genomics reportedly shutting down after CEO Austen Heinz’s death; faintly-luminescent plant product never shipped.