- A Reddit post claiming spicy-food consumption correlates with human longevity sparked discussion on low-cost dietary life-extension interventions.  
- Reactivating endogenous vitamin-C synthesis via a single SNP edit was proposed; jrayhawk warned that metabolic costs and unknown NRF2-mediated oxidative-stress pathways could negate expected benefits such as muscle hypertrophy, and kanzure added the idea to the DIYHPlusWiki candidate-modification list.  
- DIY deuterium production was modeled: ~133 L of tap water yields 1 L D₂O at ~€28.50 raw-material cost, with potential annual revenue of ~€1 M under the current €1 000/L market price; participants argued that nuclear-industry secrecy and hidden subsidies (citing Princeton working paper “Heavy Subsidies in Heavy Water”) keep prices artificially high.  
- U.S. export rules allow up to 10 kg D per shipment and 200 kg per year to non-listed countries under a general license; the group sought European equivalents and small-scale licensing fees to assess legal DIY scale-up.  
- A brainstorming session on “sorting arbitrage” identified high-value, low-cost purification opportunities—substances whose purified price far exceeds dilute price—proposing a metric of (abundance × purified price)/(dilute price) and mentioning titanium isotope separation as another candidate.  
- Space-mining economics were briefly examined: Deep Space Industries’ plan to extract water in space could flood markets, but kanzure noted that delivery timing and pre-release stockpiling would determine price impact.  
- Engineering trade-offs between open-water and sealed-tube photobioreactors were debated; FourFire argued that waterproofing open ponds is costly and risky, advocating plexiglass tubes for algae or other bio-production systems.  
- Single-molecule biophysics tools were highlighted: an optical-tweezer study achieving sub-nanometer precision in tracking RNA folding pathways (phys.org, 2012) and a 1993 Science paper on a yeast p34^CDC28 kinase inhibitor (PMID 8421781) were shared as resources for synthetic-biology and life-extension research.  
- A concise Reddit comment refuting qualia was offered, linking consciousness debates to neuroscientific reductionism, while a brief exchange on quantum immortality explored the many-worlds paradox that an observer can never confirm their own death.