- NanoEngineer-1 (NE-1) is no longer a central topic in #hplusroadmap; the idea of paying Russian developers to refactor the open-source molecular CAD tool was once floated but never gained traction.

- A 2012 open-access paper (PMC3322530) was circulated arguing that major evolutionary transitions—origin of life, eukaryotes, consciousness—are best understood as abrupt network-structure phase transitions that create entirely new structure–function relationships.

- Channel members shared reverse-engineering visualization tools: the open-source binglide GitHub project, the web-based binvis.io platform, and an accompanying YouTube demonstration of binary data visualization techniques.

- A Nature Molecular Psychiatry exome-sequencing study of 1,409 ultra-high-IQ (>170) individuals found no reproducible protein-altering variants linked to extreme intelligence, yet genome-wide analysis still attributed 17.4 % of intelligence heritability to assayed exonic variation, prompting debate over whether conventional IQ tests miss heritable cognitive components like working-memory set size or spatial ability.

- DIY bio discussion included building a coffee-ground “omnigripper” balloon gripper, sourcing bulk fetal bovine serum (FBS) for cell culture, and half-serious suggestions of harvesting cow blood or “borrowing” reagents from local biohacker John Schloendorn.

- Stanford claims that a rapid core-cooling glove can produce “steroid-like” hypertrophy gains were cited, alongside a link to the strength-and-conditioning-research.com hypertrophy database.

- Miscellaneous links included a 2015 MEMS LiDAR press release for “self-driving horses” and the philosophical paper “Why you are probably not a brain in a vat.”