- Zoltan Istvan’s 2016 U.S. presidential campaign under the Transhumanist Party banner is noted as unexpectedly entertaining; the campaign site (transhumanistparty.org/ZoltanIstvan.html) is linked and discussed.  
- A new arXiv paper (1509.07175) analyzes Darwin’s reading notebooks, showing how he alternated between exploiting familiar Victorian science and exploring novel fields, with Bayesian epoch detection revealing intellectual phase shifts that outpaced broader scientific culture.  
- Multiple CRISPR/Cas9 engineering papers are highlighted: a single-lentiviral vector that delivers Cas9, a reporter, and up to four sgRNAs via Golden Gate cloning; 50 % targeted integration in Drosophila S2 cells using 29-nt homology arms; and a 27 kb, six-transcription-unit inducible memory circuit—the largest chromosomally integrated mammalian gene network reported to date.  
- A high-resolution regulatory network model for Mycobacterium tuberculosis and a historical review of endonuclease discovery are also circulated, underscoring continued interest in both pathogen systems and foundational gene-editing tools.  
- An upcoming community chat on OpenCASCADE/OCE/OCCT is scheduled for Monday 5 Oct 2015, 21:00 UTC at gitter.im/tpaviot/oce, aimed at coordinating open-source CAD kernel development.