- A KiCad-to-OSHPark conversion script was released: a Python utility that renames KiCad plot and drill files to OSHPark’s required extensions and zips them for upload (gist.github.com/nmz787/e76770c4617cf80819a0).  
- Nanopore sequencing speed variability was dissected; hypotheses ranged from base-specific electronic signatures to strand unwinding kinetics, with TwoPoreGuys’ dual-pore architecture proposed as a real-time feedback mechanism to control translocation speed.  
- A selective-breeding roadmap for neural interfaces was outlined: breed organisms whose brains exhibit surface-accessible connectivity, then use fetal brain surgery to reroute fiber tracts, reducing the need for deep implants.  
- Glucose-powered brain implants and 10 MHz ultrasound (150 µm wavelength, low tissue attenuation) were floated as alternatives to wireless power and data telemetry for long-term implants.  
- Molecular “ticker-tape” neural recording limits were quantified: DNA polymerase at 1 kHz could sustain ~100 simultaneous templates per neuron before metabolic saturation, while RNA polymerase II could reach ~1.7 k templates.  
- Mechanosynthetic DNA ligation strategies were debated, including AFM/STM tip positioning, localized THz heating, and Oyabu et al.’s 2003 silicon mechanosynthesis demonstration as a precedent.  
- Reversible DNA immobilization techniques for nanoscale manipulation were catalogued: van-der-Waals forces, biotin–streptavidin, aptamers, antibodies, and click-chemistry to anchor strands while leaving complementary ends free for ligation.  
- Arduino 101 (Intel Curie) was identified as a low-cost prototyping platform for bio-sensors, alongside DIY silicon wet-etch recipes (KOH, HF) to enable low-cost lithography for bio-nanotech devices.  
- Extreme hydrocephalus cases with ~95 % CSF replacement yet normal-to-high IQs were cited to question neural redundancy and the minimal substrate required for human-level intelligence.