- Open-source 3-D-printable micropipettes (Thingiverse designs 255519 and 159052) were evaluated and found to fall short of commercial accuracy; milligram-scale calibration is recommended as the best DIY validation method.  
- A concept for an ultra-low-cost, high-throughput small-molecule screening platform was sketched: open-source liquid-handling robotics, 3-D-printed lenses for optical readout, and standard 1536-well plates, aimed at democratizing drug discovery.  
- “Concordance screening” was proposed—using large panels of molecules with known in-vivo efficacy to empirically pick in-vitro assays that best predict real-world drug responses, especially for diseases like Alzheimer’s where clinical attrition is high.  
- Curcumin and berberine were discussed as dual Nrf2-activating, anti-cancer compounds with poor bioavailability; piperine was noted as a simple enhancer, and berberine’s equivalence to metformin in a Phase-3 diabetes trial was cited as evidence of mainstream adoption.  
- Planaria research from the Lobo Lab was highlighted: transient gap-junction blockade can stochastically switch regenerating flatworms to other species-specific head morphologies, suggesting bioelectric networks as a programmable morphogenetic control layer.  
- A cryopreservation protocol for adherent endothelial cells (PLOS ONE, 10.1371/journal.pone.0142828) achieved 81 % post-vitrification recovery by mathematically optimizing glycerol addition/removal steps at modest cooling/warming rates, with potential extension to tissues and organs.