• Motor-cortex neurons encode complete movement trajectories rather than instantaneous kinematic parameters, implying that smooth motion relies on large, temporally-coordinated neural populations firing in rapid succession.  
• A curated set of open-access papers on basal-ganglia/cortical dynamics, reward-modulated Hebbian learning in chaotic networks, spatiotemporal memory in dissociated cortical cultures, and nucleus-accumbens value-to-goal mapping was shared for deeper study.  
• Continuous Liquid Interface Production (CLIP) stereolithography was discussed; participants noted that the underlying oxygen-inhibited resin-curing physics is not patent-protected and can be replicated without proprietary membrane materials.  
• Rimonabant, a withdrawn CB1-receptor inverse agonist linked to severe depression and suicidal ideation, was proposed as a self-experiment candidate with peer monitoring, though safety concerns were strongly voiced.  
• Ethereum vs. Bitcoin debate concluded that sidechains and auxiliary blocks (e.g., Rootstock, XCP) offer safer, value-secure ways to add complex scripting than launching new blockchains.  
• A Google-Forms-based Wiley/Biopolymers paper-request service was circulated, illustrating ongoing informal open-access efforts within the channel.  
• Recent optogenetics advances highlighted include two-photon single-cell control with sculpted light, flexible parylene-film waveguide arrays for in-vivo illumination, and simultaneous all-optical stimulation/recording at cellular resolution.  
• Microchip patch-clamp amplifiers capable of single-ion-channel recording were identified as a path to high-throughput, automated electrophysiology for circuit mapping.  
• A review on “Specification of synaptic connectivity by cell surface interactions” details how cadherins, protocadherins, and neurexins act as molecular “zip codes” guiding precise synapse formation.  
• CLARITY-based clearing methods and derivatives (e.g., CUBIC) are producing high-contrast whole-brain imaging datasets, bridging molecular synaptic specificity to macro-scale connectomic patterns relevant for brain emulation and cognitive enhancement.