• Nathan McCorkle open-sourced complete pinout diagrams, firmware settings, and an ISP-based workflow for the NEJE Laser Etcher, enabling low-cost PCB and stencil fabrication at http://diyhpl.us/laser_etcher/NEJE_Laser_Etcher/atmega_pinout.png.

• A curated GitHub repository of longevity and anti-aging studies (https://github.com/CoolerVoid/anti-aging_studies) was shared, alongside pointers to Bryan Bishop’s longevity paper archive and FightAging.org as deeper resources.

• IARPA issued an RFI on “Data Ingress and Egress for Cryogenic Systems,” signaling federal interest in scalable data handling for cryonics and brain preservation workflows.

• Channel members debated whether near-term plastination plus high-resolution brain scanning could soon exceed the fidelity of today’s vitrification, questioning if cryonics should be bypassed in favor of immediate scanning approaches.

• Cutting-edge neural interface papers discussed included ultrasonic “neural dust” motes, soft-material BCIs, optogenetics for millisecond-scale optical control, and scalable biological interface design.

• A home STM was built for under $1 000 (future iterations ~$350–500) using a 12 mm piezo tube for 1 µm³ travel, mechanically-sheared Pt/Ir tips, and constant-current feedback via inexpensive op-amps, producing sub-micron gold surface images in ambient air.

• Mechanically-driven DNA ligation on planar surfaces was deemed feasible; participants requested fixtures or nanopore constraints to extend the technique to complex 3-D DNA structures.

• MIT’s open-source Reaction Mechanism Generator (RMG-Py) and its combustion kinetics database were highlighted as tools for automated chemical reaction discovery.

• Aubrey de Grey released a new video (https://www.youtube.com/watch?v=C1zr6JsS5t8) evaluating BioViva’s recent life-extension claims, circulated for community critique.

• The channel’s living wiki (http://diyhpl.us/wiki/hplusroadmap) was pointed out as the central roadmap for open-source transhumanist projects, covering cryonics, brain preservation, nootropics, and low-cost AFM/STM resources.