- A debate on cryonics reliability and resuscitation feasibility: kanzure argues that current cryonics corpsicles may already be unrecoverable with present tech, that resuscitation could be automated by engineered machines independent of future economic climates, and that “complete brain repair” is an ill-defined requirement.  
- Neural-network pruning research surfaced: kanzure, maaku and justanotheruser exchanged IEEE and arXiv links (e.g., “Structured Pruning of Deep Convolutional Neural Networks”, 2015) and noted that DeSTIN/OpenCog uses “centroid removal” to slim networks after training.  
- Practical fabrication resources shared: heath posted GitHub repos for container-deployment tools (New Relic’s Centurion and Spotify’s Helios); kanzure explained that emachineshop is CAD-to-quote software, while most local machine shops accept standard CAD files.  
- Intel Innovation Hub in Portland, OR was highlighted by nmz787_i as offering open-access digital-fabrication gear including laser cutters, multiple 3-D printers, PCB mills, embroidery machines, and on-site vending of prototyping supplies.  
- Health & pharmacology discussion: Mori4rty asked about gastrointestinal side-effects from abrupt cessation of 300 mg XR Venlafaxine; jrayhawk_ noted that 95 % of serotonin is synthesized and used for anti-inflammatory signaling in the gut, linking SSRI withdrawal to GI distress.  
- A fractal-future.net essay on “how not to be transhumanist slack” was linked by Mori4rty, prompting a heated exchange with kanzure over David Pearce’s productivity and influence within transhumanist circles.  
- kanzure posted a Waterloo computational-neuroscience publications page and a 2014 dissertation on “Hierarchical reinforcement learning in a biologically plausible neural architecture.”  
- Scienceforthemasses.org blog post “At the end of two conferences, some thoughts” was shared by nildicit, summarizing reflections from recent biohacker gatherings.