- **High-bandwidth BCI feasibility debated**: nmz787_i argues that GHz-scale neural recording is now cheap enough (sub-$1 k per channel) to test whether microsecond timing can enable 3-D signal localization and high-data-rate brain-computer interfaces, dismissing EEG bandwidth as inadequate for direct BCI work.  
- **Open-source electroporation hardware shared**: kanzure links to the $2 k “MammoZapper” handheld electroporator and an open-e-mail thread proposing a low-cost, non-salty bacterial electroporator design.  
- **Cryonics LN₂ economics clarified**: streety corrects misconceptions that liquid nitrogen is “subsidized”; explains that at large scale cryonics organizations would simply run on-site air-separation plants, with costs scaling roughly with energy prices rather than mythical subsidies.  
- **MEMS as near-term nanomedicine platform**: maaku proposes that biocompatible MEMS sensors/drug-delivery devices could deliver many “nanomedicine” functions sooner than true nanotech, suggesting an implantable blood-glucose MEMS sensor as a profitable first product.  
- **DIY nitrate photometer project**: nmz787_i highlights a PLOS ONE paper and accompanying GitHub repo for an open-source photometric nitrate test kit, noting that promised hardware design files (schematics, CAD) appear to be missing despite the paper’s data-availability statement.  
- **Polyphasic sleep skepticism**: multiple participants warn that extreme polyphasic schedules lack empirical support; xentrac_ links a Vice article on the original “Uberman” practitioner and a SuperMemo critique, while maaku cites mainstream sleep research predicting cognitive impairment.  
- **Decentralizing scientific publishing**: ybit posts a Google Doc from the Decentralized Web Summit asking how to decentralize journals; maaku responds that “put it in git and mirror it” already solves the technical problem.  
- **Neil Harbisson cyborg art profile**: nmz787_i shares a Guardian article on the color-to-sound skull-implanted antenna artist, framing him as the “world’s first cyborg artist.”