- A $250 M Chinese “Human Genome Project reboot” is targeting an electronically-controlled DNA polymerase (or alternative chemistry) able to synthesize contiguous 1 000 bp → 1 000 000 bp fragments without post-assembly; IP ownership and ITAR/bioweapon-export compliance are still under negotiation.

- Participants debated trade-offs between slow, massively-parallel synthesis (≈10 000 reactors) versus single-reactor speed, and whether open-source licensing can survive Chinese funding.

- nmz787 sketched a micro/nanofluidic single-molecule DNA-synthesis chip: terminal deoxynucleotidyl transferase (TdT) sits behind a physical strainer; laser-induced temperature pulses gate nucleotide incorporation; electronic length verification lets erroneous strands be trimmed or discarded in situ.

- CaptHindsight reported that second-generation ink-jet DNA printers can be built from off-the-shelf heads and offered to release the design openly for low-cost mass production in China.

- Autodesk Research is preparing to treat its first canine patient with oncolytic synthetic viruses and envisions a disposable “gene-therapy e-pen” that would synthesize DNA, package it into a viral vector, and electroporate tissue in a single use.

- Concerns were raised that Oxford Nanopore’s foundational nanopore-sequencing patents are nearing expiration and that ITAR controls could restrict export of synthetic-biology reagents.

- nmz787 is prototyping a MicroPython-driven STM Nucleo F401 electroporation controller; early LED-dimming tests failed, suggesting microsecond-scale GPIO toggling will require inline assembly.

- A literature dump shared papers on light-activated, electronically gated, and template-independent polymerases, plus proposals for remote electronic control of DNA hybridization via metal-nanocrystal antennas.