• UC and Broad Institute clashed in court over CRISPR patents: UC argued six labs—including Doudna’s—proved CRISPR works in eukaryotes within six months of the foundational paper, while Broad countered that Doudna herself admitted “many frustrations” getting it to function in human cells.

• kelu124 released “murgen,” a two-breadboard DIY ultrasound dev-kit using an STM32 on an Adafruit Wi-Fi board; kits are already on Tindie and documented in arXiv paper 1611.10174.

• Channel debated synthetic-aperture and time-reversal ultrasound imaging as math-based alternatives to large phased arrays, enabling full-field, high-frame-rate scans with a single element.

• Participants explored open-hardware ultrasound applications beyond imaging: body-fat measurement, stroke-rehabilitation biofeedback, and microbubble-mediated targeted drug delivery triggered by ultrasound.

• Ligandal’s peptide nanotechnology claims to deliver CRISPR, TALEN and RNA cargoes to specific cells and organelles without viral vectors, positioning itself as a next-generation precision gene-therapy platform.

• Phage-Assisted Continuous Evolution (PACE) was presented as a method that hijacks bacteriophage replication to evolve proteins or nucleic acids in vivo by linking phage infectivity to the desired molecular activity.

• A Nature study on 40 Hz gamma entrainment reducing amyloid load and modulating microglia was circulated as a possible non-invasive intervention for Alzheimer’s disease.

• Engineered “enveloped protein nanocages” (EPNs) that self-assemble and bud from human cells inside extracellular vesicles were proposed as virus-mimicking vehicles for drug or gene delivery.

• kanzure floated “mutantpedia,” a crowdsourced catalog of naturally occurring human mutations like the DEC2 short-sleeper gene, which may confer ~40 % effective lifespan extension by reducing required sleep, deliverable via CRISPR/lentivirus or oral vectors.