- RebelBio (formerly IndieBio EU) was announced as “the world’s first biotech accelerator,” prompting discussion about Cathal Garvey’s exact role with the program and his separate IndieBioTech consultancy.  
- Participants debated why ultrasound hardware remains expensive, citing low demand for specialty materials like PZT thin films and lack of economies of scale, and floated the idea of an open-hardware PCB that bundles ultrasound circuitry with other niche instruments.  
- nmz787 shared progress on modeling a next-generation DNA-synthesis nano-sieve: a 3 mm × 100 µm silicon-nitride frame containing a 500 × 500 µm window of 20 nm-thick membrane pierced by 30 nm pores on a 120 nm grid, with macro-scale visual alignment features.  
- A review of microfluidic valve architectures was circulated (PDF link) while nmz787 sought advice on choosing an on-chip pump design for a simple “hello-world” demo that would drive colored water through letter-shaped channels.  
- kanzure posted a reading list covering directed-evolution selection methods for homing endonucleases, single-molecule DNA-repair techniques, and yeast-based homologous-recombination cloning protocols that require only 30–50 bp homology regions.