- The Dorset (Palaeo-Eskimo) culture is proposed as a natural experiment in extreme cold adaptation: surviving Arctic winters at –30 °C without wood fuel or sea-mammal oil suggests possible genetic torpor/hibernation-like mechanisms, an idea explicitly tied to Neanderthal survival strategies.  
- DIYhpluswiki was updated with a curated list of human SNPs linked to quantifiable cognitive traits: WWC1/KIBRA (19–24 % boost in free-recall memory), hippocampal volume regulators, sleep-duration genes, and hearing-loss variants—each annotated with rsIDs and phenotypic effect sizes.  
- Participants debated the functional impact of single-nucleotide changes, noting that many cognition-associated SNPs fall inside protein-coding regions and that evolutionary timescales make single-point mutations the primary lever for large phenotypic shifts.  
- A concrete gene-transfer proposal emerged: introduce the human WWC1 allele (99.5 % identical to chimp) into chimpanzees and dogs to test whether the memory-enhancing phenotype is recapitulated in non-human brains.  
- Discussion highlighted the difficulty of selecting neural metabolic targets for enhancement; AMPA-receptor trafficking was raised as a candidate but deemed hard to optimize without clearer limiting-pathway data.  
- The channel referenced external resources including SNPedia (rs17070145), NCBI HomoloGene, MGI mouse homology records, and the Orion’s Arm “Utility Fog” world-building article as speculative background material.