• The FDA is soliciting public comments (docket FDA-2008-D-0394-0279) on its stepped-up enforcement against “rogue” DIY genetic engineers, signaling heightened regulatory scrutiny of citizen bioengineering.  
• A 2008 PNAS paper describing one-step yeast assembly of the 592 kb synthetic Mycoplasma genitalium genome was dissected; participants argued that yeast DNA-uptake limits could be bypassed by microinjection to solve the “collector’s problem.”  
• Google’s free “Site Reliability Engineering” book and its chapter on managing on-call interrupts were circulated, together with the associated Hacker News discussion, as a model for scaling reliable bio-IT infrastructure.  
• Bunnie Huang’s essay mapping influenza virology onto computer-security concepts (NOP sleds, RNA subroutines) was praised as an accessible bridge for engineers entering virology.  
• A DIY LCD-mask SLA 3-D printer project was proposed for micro-fabrication, with participants pointing to open-source laser-etcher designs on diyhpl.us and plans to add reduction optics.  
• The channel surveyed longevity and cognitive-enhancement compounds, highlighting selegiline, metformin, NSI-189 (unknown molecular target discovered via 10,269-compound screen), rapastinel, cerebrolysin (porcine brain peptide mix with BDNF, GDNF, NGF, CNTF), and semax.  
• Participants debated whether the rumored “$100 Illumina genome” is imminent or still speculative, concluding it remains in the “maybe” category.